FI46163B - - Google Patents

Info

Publication number
FI46163B
FI46163B FI2416/64A FI241664A FI46163B FI 46163 B FI46163 B FI 46163B FI 2416/64 A FI2416/64 A FI 2416/64A FI 241664 A FI241664 A FI 241664A FI 46163 B FI46163 B FI 46163B
Authority
FI
Finland
Application number
FI2416/64A
Other languages
Finnish (fi)
Other versions
FI46163C (fi
Inventor
G Regnier
R Canevari
M Laubie
Original Assignee
Science Union & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union & Cie filed Critical Science Union & Cie
Application granted granted Critical
Publication of FI46163B publication Critical patent/FI46163B/fi
Publication of FI46163C publication Critical patent/FI46163C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI642416A 1963-11-19 1964-11-18 Menetelmä uusien, vasodilaattoreina ja tulehdusta estävinä aineina ter apeuttisesti tehokkaiden pyrimidiinijohdannaisten ja niiden additiosuo lojen valmistamiseksi. FI46163C (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB45685/63A GB1101425A (en) 1963-11-19 1963-11-19 New pyrimidine derivatives

Publications (2)

Publication Number Publication Date
FI46163B true FI46163B (xx) 1972-10-02
FI46163C FI46163C (fi) 1973-01-10

Family

ID=10438157

Family Applications (1)

Application Number Title Priority Date Filing Date
FI642416A FI46163C (fi) 1963-11-19 1964-11-18 Menetelmä uusien, vasodilaattoreina ja tulehdusta estävinä aineina ter apeuttisesti tehokkaiden pyrimidiinijohdannaisten ja niiden additiosuo lojen valmistamiseksi.

Country Status (14)

Country Link
US (1) US3299067A (xx)
AT (1) AT255421B (xx)
BE (1) BE655431A (xx)
BR (1) BR6464358D0 (xx)
CH (1) CH437310A (xx)
DE (1) DE1297610B (xx)
DK (1) DK115995B (xx)
ES (1) ES306226A1 (xx)
FI (1) FI46163C (xx)
FR (1) FR4770M (xx)
GB (1) GB1101425A (xx)
NL (2) NL6413349A (xx)
NO (1) NO115800B (xx)
SE (1) SE322521B (xx)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
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US3980781A (en) * 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
GB1143167A (en) * 1967-01-25 1969-02-19 Ucb Sa Derivatives of pyrimidine
GB1369379A (en) * 1972-04-07 1974-10-09 Science Union & Cie Benzodioxole derivatives and processes for preparing them
US3919230A (en) * 1974-02-07 1975-11-11 Smithkline Corp {62 -Naphthylmethyl piperazinyl derivatives
US3988457A (en) * 1974-02-07 1976-10-26 Smithkline Corporation Novel compounds and compositions for treating Parkinson's disease
US3960863A (en) * 1974-06-25 1976-06-01 Sankyo Company Limited Pyrido[1,2-a]pyrimidinone derivatives
US4166852A (en) * 1974-08-09 1979-09-04 Produits Chimiques Ugine Kuhlmann Piperazino-pyrimidines and their use as spasmolytic agents
OA06083A (fr) * 1977-11-09 1981-06-30 Science Union & Cie Ste Franca Nouvelles pipérazines disubstituées, leurs procédés de préparation et les compositions pharmaceutiques les renfermant.
FR2519986A1 (fr) * 1982-01-21 1983-07-22 Adir Nouveaux derives de benzodioxine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
FR2539990A1 (fr) * 1983-01-28 1984-08-03 Sanofi Sa Composition pharmaceutique a action psychotrope dopaminergique contenant une 2-piperazinopyrimidine
US4605655A (en) * 1984-03-06 1986-08-12 Bristol-Myers Company Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives
US4980350A (en) * 1988-02-25 1990-12-25 Merck & Co., Inc. Piperazinylalkylpyrimidines as hypoglycemic agents
EP0330263A1 (en) * 1988-02-25 1989-08-30 Merck & Co. Inc. Piperazinylalkylpyrimidines as hypoglycemic agents
US4994460A (en) * 1989-06-01 1991-02-19 Bristol-Myers Squibb Co. Agents for treatment of brain ischemia
US5859246A (en) * 1997-01-30 1999-01-12 Neurogen Corporation 1-phenyl-4-benzylpiperazines: dopamine receptor subtype specific ligands
DE69836559T2 (de) * 1997-09-29 2007-09-13 Aventis Pharmaceuticals Inc. Aminoalkylphenol-derivate zur behandlung von depression und gedächtnis-funktionsstörung
US6825198B2 (en) * 2001-06-21 2004-11-30 Pfizer Inc 5-HT receptor ligands and uses thereof
ATE502635T1 (de) 2002-08-19 2011-04-15 Pfizer Kombinationstherapie gegen hyperproliferative erkrankungen
US20050209231A1 (en) * 2004-01-16 2005-09-22 Xu Wu Compositions and methods for inducing cardiomyogenesis
US7241891B2 (en) * 2004-03-29 2007-07-10 Chung-Shan Institute Of Science & Technology Method for the purification of Piribedil
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体
CN101735201B (zh) * 2009-12-17 2012-05-30 宁夏康亚药业有限公司 一种吡贝地尔的制备方法
CN101830891A (zh) * 2010-05-18 2010-09-15 沈阳药科大学 一种吡贝地尔的制备方法
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのｎ−ピペリジン−３−イルベンズアミド誘導体
US10336775B2 (en) 2014-08-28 2019-07-02 Asceneuron Sa Glycosidase inhibitors
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
IL260638B1 (en) 2016-02-25 2024-09-01 Asceneuron S A Acidic addition salts of piperazine derivatives
MX2018010191A (es) 2016-02-25 2019-05-20 Asceneuron S A Inhibidores de glucosidasa.
EP3585783A2 (en) 2016-02-25 2020-01-01 Asceneuron SA Sulfoximine glycosidase inhibitors
US11261183B2 (en) 2016-02-25 2022-03-01 Asceneuron Sa Sulfoximine glycosidase inhibitors
WO2017144633A1 (en) 2016-02-25 2017-08-31 Asceneuron S. A. Glycosidase inhibitors
CN106432212B (zh) * 2016-09-21 2019-01-11 苏州弘森药业股份有限公司 一种合成吡贝地尔的方法
CN107216318A (zh) * 2017-06-19 2017-09-29 太仓弘杉环保科技有限公司 一种吡贝地尔制备方法
CN107266429A (zh) * 2017-06-19 2017-10-20 太仓大唐化纤厂 一种高品质的吡贝地尔制备方法
CN107163032A (zh) * 2017-06-19 2017-09-15 太仓卡斯特姆新材料有限公司 一种高收率的吡贝地尔制备方法
CN107417674B (zh) * 2017-06-26 2020-12-29 苏州弘森药业股份有限公司 一种吡贝地尔的提纯方法
WO2019037860A1 (en) 2017-08-24 2019-02-28 Asceneuron S.A. LINEAR INHIBITORS OF GLYCOSIDASE
EP3672958B1 (en) 2017-08-24 2023-08-02 Asceneuron SA Annulated glycosidase inhibitors
RU2737721C2 (ru) * 2017-12-15 2020-12-02 Алексей Георгиевич Александров Способ получения фармацевтической субстанции на основе пирибедила
WO2020039027A1 (en) 2018-08-22 2020-02-27 Asceneuron S. A. Pyrrolidine glycosidase inhibitors
US11731972B2 (en) 2018-08-22 2023-08-22 Asceneuron Sa Spiro compounds as glycosidase inhibitors
US11795165B2 (en) 2018-08-22 2023-10-24 Asceneuron Sa Tetrahydro-benzoazepine glycosidase inhibitors
JP7128969B2 (ja) 2019-01-18 2022-08-31 アストラゼネカ・アクチエボラーグ Ｐｃｓｋ９阻害剤及びその使用方法
US20220143042A1 (en) 2019-02-22 2022-05-12 Asceneuron Sa Fused glycosidase inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE485737A (xx) * 1947-11-12
DE942029C (de) * 1951-06-22 1956-04-26 American Cyanamid Co Verfahren zur Herstellung von neuen, in 1-Stellung substituierten 4-Aminopiperazinderivaten
US3078214A (en) * 1958-09-12 1963-02-19 Sandoz Ag Treatment of mental disturbances with esters of indoles
US2985657A (en) * 1959-10-12 1961-05-23 Paul A J Janssen 1-(aroylalkyl)-4-heterocyclylpiperazines
US2979508A (en) * 1959-10-12 1961-04-11 Paul A J Janssen Heterocyclic derivatives of 1-phenyl-omega-(piperazine) alkanols
US3141820A (en) * 1960-10-31 1964-07-21 Merck & Co Inc Coccidiosis control composition
BE618035A (xx) * 1961-05-26
US3144387A (en) * 1961-06-30 1964-08-11 Parke Davis & Co Anti-inflammatory compositions

Also Published As

Publication number Publication date
DK115995B (da) 1969-12-01
NL127996C (xx)
FI46163C (fi) 1973-01-10
AT255421B (de) 1967-07-10
NO115800B (xx) 1968-12-09
BR6464358D0 (pt) 1973-07-26
DE1297610B (de) 1969-06-19
FR4770M (xx) 1967-01-23
NL6413349A (xx) 1965-05-20
CH437310A (fr) 1967-06-15
GB1101425A (en) 1968-01-31
US3299067A (en) 1967-01-17
ES306226A1 (es) 1965-03-01
SE322521B (xx) 1970-04-13
BE655431A (xx) 1965-05-06

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