FI45446B - - Google Patents

Info

Publication number
FI45446B
FI45446B FI1886/65A FI188665A FI45446B FI 45446 B FI45446 B FI 45446B FI 1886/65 A FI1886/65 A FI 1886/65A FI 188665 A FI188665 A FI 188665A FI 45446 B FI45446 B FI 45446B
Authority
FI
Finland
Application number
FI1886/65A
Other languages
Finnish (fi)
Other versions
FI45446C (fi
Inventor
H Morren
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Application granted granted Critical
Publication of FI45446B publication Critical patent/FI45446B/fi
Publication of FI45446C publication Critical patent/FI45446C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
FI651886A 1964-08-06 1965-08-05 Menetelmä uusien fysiologisesti vaikuttavien N-substituoitujen laktaam ien valmistamiseksi FI45446C (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB32037/64A GB1039113A (en) 1964-08-06 1964-08-06 New n-substituted lactams

Publications (2)

Publication Number Publication Date
FI45446B true FI45446B (xx) 1972-02-29
FI45446C FI45446C (fi) 1972-06-12

Family

ID=10332139

Family Applications (1)

Application Number Title Priority Date Filing Date
FI651886A FI45446C (fi) 1964-08-06 1965-08-05 Menetelmä uusien fysiologisesti vaikuttavien N-substituoitujen laktaam ien valmistamiseksi

Country Status (15)

Country Link
US (1) US3459738A (xx)
AT (2) AT258260B (xx)
BE (1) BE667906A (xx)
CH (1) CH436304A (xx)
CY (1) CY727A (xx)
DE (1) DE1620608C3 (xx)
DK (1) DK121174B (xx)
ES (1) ES316156A1 (xx)
FI (1) FI45446C (xx)
FR (2) FR1478349A (xx)
GB (1) GB1039113A (xx)
IL (1) IL24082A (xx)
IT (1) IT1052776B (xx)
NL (1) NL148313B (xx)
SE (1) SE308526B (xx)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1309692A (en) * 1970-02-13 1973-03-14 Ucb Sa N-substituted lactams
FR2059985A1 (en) * 1969-08-29 1971-06-11 Synthelabo 4-benzyl piperidine 2,6-dione derivs
US4081456A (en) * 1973-02-28 1978-03-28 Mobil Oil Corporation Bis-lactam derivatives
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
AT360980B (de) * 1976-01-14 1981-02-10 Pliva Pharm & Chem Works Verfahren zur herstellung von n-alkylamiden des 2-oxo-1-pyrrolidins
US4069336A (en) * 1976-02-25 1978-01-17 Chemisches Laboratorium Fritz-Walter Lange Gmbh & Co Kg (2-oxo-pyrrolidines)-acetic hydrazides
GB1583871A (en) * 1976-10-19 1981-02-04 Ucb Sa Anti-aggregants
GB1539817A (en) * 1976-10-22 1979-02-07 Ucb Sa N-substituted lactams
GB1582351A (en) * 1977-02-10 1981-01-07 Ucb Sa Disubstituted ureas and thioureas
DE2757680A1 (de) * 1977-12-23 1979-06-28 Troponwerke Gmbh & Co Kg Neue 2-oxo-1-pyrrolidinessigsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
CA1115212A (en) 1978-02-10 1981-12-29 Emilio Kyburz Pyrrolidine derivatives
EP0005689B1 (fr) 1978-05-08 1981-03-18 U C B, S.A. Nouveaux acides lactame-N-acétiques et leurs amides, leurs procédés de préparation et compositions thérapeutiques
IT1141287B (it) * 1979-06-13 1986-10-01 Nattermann A & Cie Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono
DE2924011C2 (de) 1979-06-13 1982-04-08 A. Nattermann & Cie GmbH, 5000 Köln Pyrrolidin-(2)-on-(1)-ylessigsäure-2,6,-dimethylanilid, Verfahren zur Herstellung und Arzneimittel, welche diese Verbindung enthalten
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
EP0089900B1 (en) * 1982-03-24 1985-12-27 Prodes S.A. New n-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts
US4525476A (en) * 1983-05-26 1985-06-25 Warner-Lambert Company N-[1-oxo-3-(5-oxo-2-pyrrolidinyl)propyl]-alpha-aminoacids and derivatives as cognition activators
DE3326724A1 (de) * 1983-07-25 1985-02-07 Boehringer Ingelheim KG, 6507 Ingelheim In 1-stellung substituierte 4-hydroxymethyl-pyrrolidinone, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen und zwischenprodukte
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
DE3420193A1 (de) * 1984-05-30 1985-12-05 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte pyrrolidinone, verfahren zu ihrer herstellung und arzneimittel
FI83510C (fi) * 1985-02-22 1991-07-25 Ciba Geigy Ag Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara bi-2h- pyrroli(di)ndioner.
PH23078A (en) * 1986-01-30 1989-04-10 Ciba Geigy Ag Substituted pyrrolidinones
IT1224168B (it) * 1986-08-01 1990-09-26 Finanziaria R F Spa Ora Finanz Derivati del pirrolidin-2-one ad attivita' nootropa
US4990513A (en) * 1987-02-06 1991-02-05 S O "Pharmachim" Antihypoxic drug and method of its application
WO1988009330A1 (en) * 1987-05-20 1988-12-01 Zambon Group S.P.A. Isoxazoles with nootropic activity
JPS6422883A (en) * 1987-07-17 1989-01-25 Sanwa Kagaku Kenkyusho Co 1-pyrrolidine acetamide derivative, its salt, production thereof and prophylactic and remedial agent for cereral dysfunction containing said derivative and salt as active ingredient
JP2660201B2 (ja) * 1988-08-05 1997-10-08 塩野義製薬株式会社 新規ピロロ［１，４］ベンゾジアゼピン誘導体および老人性痴呆薬
FI102748B (fi) * 1992-06-19 1999-02-15 Daiichi Seiyaku Co Menetelmä N-(2,6-dialkyylifenyyli)-2-(2-okso-1-pyrrolidinyyli)asetamid ijohdannaisen valmistamiseksi
CN1041630C (zh) * 1994-01-13 1999-01-13 北京大学 合成α-吡咯烷酮乙酰胺的方法
US5912189A (en) * 1998-05-12 1999-06-15 The Lubrizol Corporation Compositions containing reaction product of a cyclic compound containing both a nitrogen atom and a carbonyl group, an aldehyde or ketone, and an etheramine
GB0004297D0 (en) * 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
JPWO2002053153A1 (ja) * 2000-12-28 2004-04-30 第一製薬株式会社 神経因性疼痛治療及び予防薬
PE20091564A1 (es) 2008-02-29 2009-11-04 Biolab Sanus Farmaceutica Ltda Composicion farmaceutica de un derivado racetam y carnitina
AU2009303834B2 (en) 2008-10-16 2016-08-11 The Johns Hopkins University Methods and compositions for improving cognitive function
PL389364A1 (pl) 2009-10-23 2011-04-26 Uniwersytet Jagielloński Nowe zastosowanie pochodnych 2-pirolidonu
CN102905532A (zh) 2010-02-09 2013-01-30 约翰斯.霍普金斯大学 用于改善认知功能的方法和组合物
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
WO2014144801A1 (en) 2013-03-15 2014-09-18 Agenebio Inc. Methods and compositions for improving cognitive function
ME03518B (me) 2014-01-21 2020-04-20 Janssen Pharmaceutica Nv Kombinacije koje obuhvataju pozitivne alosterične modulatore ili ortosterične agoniste metabotropnog glutamatergičnog receptora podtipa 2 i njihova primjena
WO2015110435A1 (en) 2014-01-21 2015-07-30 Janssen Pharmaceutica Nv Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
BR112019011208A2 (pt) 2016-12-16 2019-10-15 Idorsia Pharmaceuticals Ltd combinação farmacêutica, composição farmacêutica, e, kit de partes.
EA037205B1 (ru) * 2019-05-20 2021-02-19 Дмитрий Сергеевич Валуев Способ получения 2-(2-оксопирролидин-1-ил)-n-фенилацетамида
WO2024039886A1 (en) 2022-08-19 2024-02-22 Agenebio, Inc. Benzazepine derivatives, compositions, and methods for treating cognitive impairment

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE592979A (xx) * 1959-07-14
US3185678A (en) * 1961-08-04 1965-05-25 Colgate Palmolive Co Polymethyleniminoalkylamides
US3250784A (en) * 1963-12-23 1966-05-10 Gen Aniline & Film Corp Pyrrolidonyl-gamma-butyramide and process of preparing

Also Published As

Publication number Publication date
FR1478349A (fr) 1967-04-28
AT258260B (de) 1967-11-10
CY727A (en) 1974-03-01
NL148313B (nl) 1976-01-15
US3459738A (en) 1969-08-05
AT261599B (de) 1968-05-10
DE1620608A1 (de) 1970-04-30
IL24082A (en) 1969-02-27
SE308526B (xx) 1969-02-17
GB1039113A (en) 1966-08-17
FI45446C (fi) 1972-06-12
BE667906A (xx) 1966-02-07
DK121174B (da) 1971-09-20
CH436304A (fr) 1967-05-31
DE1620608B2 (de) 1975-01-30
ES316156A1 (es) 1965-11-16
DE1620608C3 (de) 1975-09-25
NL6509994A (xx) 1966-02-07
IT1052776B (it) 1981-07-20
FR7119M (xx) 1969-07-21

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