FI3638277T3 - Koostumukset ja menetelmät beetasekretaasin estämiseksi - Google Patents
Koostumukset ja menetelmät beetasekretaasin estämiseksi Download PDFInfo
- Publication number
- FI3638277T3 FI3638277T3 FIEP18816475.0T FI18816475T FI3638277T3 FI 3638277 T3 FI3638277 T3 FI 3638277T3 FI 18816475 T FI18816475 T FI 18816475T FI 3638277 T3 FI3638277 T3 FI 3638277T3
- Authority
- FI
- Finland
- Prior art keywords
- weight
- composition
- oroxylin
- chrysin
- baicalein
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
- Confectionery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762520141P | 2017-06-15 | 2017-06-15 | |
| PCT/US2018/037454 WO2018232063A1 (en) | 2017-06-15 | 2018-06-14 | Compositions and methods for beta secretase inhibition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI3638277T3 true FI3638277T3 (fi) | 2025-01-10 |
Family
ID=64655980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FIEP18816475.0T FI3638277T3 (fi) | 2017-06-15 | 2018-06-14 | Koostumukset ja menetelmät beetasekretaasin estämiseksi |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11458117B2 (https=) |
| EP (2) | EP3638277B1 (https=) |
| JP (2) | JP7209645B2 (https=) |
| KR (2) | KR20190134809A (https=) |
| CA (2) | CA3063751C (https=) |
| ES (1) | ES3005508T3 (https=) |
| FI (1) | FI3638277T3 (https=) |
| PL (2) | PL3638277T3 (https=) |
| WO (2) | WO2018232063A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES3005508T3 (en) * | 2017-06-15 | 2025-03-14 | Sami Labs Ltd | Compositions and methods for beta secretase inhibition |
| US12465585B2 (en) * | 2018-06-15 | 2025-11-11 | Sami-Sabinsa Group Limited | Compositions for the management of seizure induced neurotoxicity |
| CN110115712A (zh) * | 2019-07-04 | 2019-08-13 | 兰州大学 | 一种同时激活氧化磷酸化通路和抑制糖酵解途径的激活剂及其应用 |
| CN114630650B (zh) * | 2019-08-26 | 2024-03-29 | 萨米-萨宾莎集团有限公司 | 植物活性物及其防污染效果 |
| CN114246879B (zh) * | 2021-12-30 | 2023-10-27 | 沈阳兴齐眼药股份有限公司 | 木蝴蝶苷b在制备用于预防、控制和/或治疗眼部疾病药物中的用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101837003B (zh) * | 2002-04-30 | 2013-09-04 | 尤尼根公司 | 作为治疗剂的包含无取代b环类黄酮和黄烷混合物的组合物 |
| US8945518B2 (en) * | 2002-04-30 | 2015-02-03 | Unigen, Inc. | Formulation of dual eicosanoid system and cytokine system inhibitors for use in the prevention and treatment of oral diseases and conditions |
| US8034387B2 (en) * | 2002-04-30 | 2011-10-11 | Unigen, Inc. | Formulation of a mixture of free-B-ring flavonoids and flavans for use in the prevention and treatment of cognitive decline and age-related memory impairments |
| MXPA06002456A (es) * | 2003-09-02 | 2006-08-31 | Unigen Pharmaceuticals Inc | Formulacion de una mezcla de flavonoides con el aniillo b libre y flavanos para utilizarse en la prevencion y tratamiento de la declinacion cognoscitiva y el deterioro de la memoria relacionado con la edad. |
| US7855200B2 (en) * | 2006-01-09 | 2010-12-21 | Council Of Scientific And Industrial Research | Method for treatment of gastric ulcers and ulcers induced by aspirin |
| JP2009527541A (ja) | 2006-02-21 | 2009-07-30 | カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ | 腸管αグルコシダーゼ阻害剤ならびにその単離方法およびその使用 |
| US20100029654A1 (en) | 2006-03-23 | 2010-02-04 | Mount Sinai School Of Medicine | Cardiovascular compositions and use of the same for the treatment of alzheimer's disease |
| KR20080008929A (ko) * | 2006-11-20 | 2008-01-24 | 대한민국(관리부서 식품의약품 안전청장) | 오록실린 ａ를 함유하는 인지 기능 장애 관련 질환의 예방및 개선용 건강기능식품 |
| US20150231067A1 (en) * | 2012-08-29 | 2015-08-20 | Mannkind Corporation | Method and composition for treating hyperglycemia |
| NZ753943A (en) * | 2016-11-11 | 2021-03-26 | Sami Labs Ltd | Composition containing oroxylin a and method of extraction thereof |
| ES3005508T3 (en) | 2017-06-15 | 2025-03-14 | Sami Labs Ltd | Compositions and methods for beta secretase inhibition |
-
2018
- 2018-06-14 ES ES18816475T patent/ES3005508T3/es active Active
- 2018-06-14 CA CA3063751A patent/CA3063751C/en active Active
- 2018-06-14 WO PCT/US2018/037454 patent/WO2018232063A1/en not_active Ceased
- 2018-06-14 US US16/008,219 patent/US11458117B2/en active Active
- 2018-06-14 FI FIEP18816475.0T patent/FI3638277T3/fi active
- 2018-06-14 KR KR1020197034396A patent/KR20190134809A/ko not_active Ceased
- 2018-06-14 EP EP18816475.0A patent/EP3638277B1/en active Active
- 2018-06-14 PL PL18816475.0T patent/PL3638277T3/pl unknown
- 2018-06-14 JP JP2019568236A patent/JP7209645B2/ja active Active
- 2018-06-15 JP JP2019569247A patent/JP6796217B2/ja active Active
- 2018-06-15 EP EP18817403.1A patent/EP3638278B1/en active Active
- 2018-06-15 US US16/009,490 patent/US10894029B2/en active Active
- 2018-06-15 WO PCT/US2018/037724 patent/WO2018232224A1/en not_active Ceased
- 2018-06-15 PL PL18817403.1T patent/PL3638278T3/pl unknown
- 2018-06-15 CA CA3063757A patent/CA3063757C/en active Active
- 2018-06-15 KR KR1020197033007A patent/KR20190131589A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018232063A1 (en) | 2018-12-20 |
| EP3638278B1 (en) | 2022-05-11 |
| EP3638278A4 (en) | 2021-03-17 |
| US20180360800A1 (en) | 2018-12-20 |
| US11458117B2 (en) | 2022-10-04 |
| EP3638277A1 (en) | 2020-04-22 |
| ES3005508T3 (en) | 2025-03-14 |
| EP3638277A4 (en) | 2021-03-17 |
| WO2018232224A1 (en) | 2018-12-20 |
| CA3063751A1 (en) | 2018-12-20 |
| CA3063757C (en) | 2023-08-01 |
| KR20190134809A (ko) | 2019-12-04 |
| PL3638278T3 (pl) | 2022-10-03 |
| EP3638277B1 (en) | 2024-10-09 |
| US20180360801A1 (en) | 2018-12-20 |
| JP7209645B2 (ja) | 2023-01-20 |
| US10894029B2 (en) | 2021-01-19 |
| EP3638278A1 (en) | 2020-04-22 |
| JP2020523342A (ja) | 2020-08-06 |
| KR20190131589A (ko) | 2019-11-26 |
| JP6796217B2 (ja) | 2020-12-02 |
| PL3638277T3 (pl) | 2025-03-10 |
| JP2020523372A (ja) | 2020-08-06 |
| CA3063757A1 (en) | 2018-12-20 |
| CA3063751C (en) | 2023-01-03 |
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