FI3373976T3 - Topikaalisia formulaatioita ja niiden käyttöjä - Google Patents
Topikaalisia formulaatioita ja niiden käyttöjä Download PDFInfo
- Publication number
- FI3373976T3 FI3373976T3 FIEP16864797.2T FI16864797T FI3373976T3 FI 3373976 T3 FI3373976 T3 FI 3373976T3 FI 16864797 T FI16864797 T FI 16864797T FI 3373976 T3 FI3373976 T3 FI 3373976T3
- Authority
- FI
- Finland
- Prior art keywords
- formulation
- hco
- polyoxyl
- weight
- ophthalmic
- Prior art date
Links
- 239000012049 topical pharmaceutical composition Substances 0.000 title 1
- 238000009472 formulation Methods 0.000 claims 29
- 239000000203 mixture Substances 0.000 claims 29
- 229920002675 Polyoxyl Polymers 0.000 claims 8
- 150000002632 lipids Chemical class 0.000 claims 8
- 239000000194 fatty acid Substances 0.000 claims 6
- 235000014113 dietary fatty acids Nutrition 0.000 claims 5
- 229930195729 fatty acid Natural products 0.000 claims 5
- 150000004665 fatty acids Chemical class 0.000 claims 5
- 150000001298 alcohols Polymers 0.000 claims 3
- 229920002701 Polyoxyl 40 Stearate Polymers 0.000 claims 2
- 229920004914 octoxynol-40 Polymers 0.000 claims 2
- 229940099429 polyoxyl 40 stearate Drugs 0.000 claims 2
- 208000003556 Dry Eye Syndromes Diseases 0.000 claims 1
- 206010013774 Dry eye Diseases 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 239000000227 bioadhesive Substances 0.000 claims 1
- 239000007853 buffer solution Substances 0.000 claims 1
- 239000004359 castor oil Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002335 preservative effect Effects 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562253569P | 2015-11-10 | 2015-11-10 | |
| PCT/US2016/060391 WO2017083167A1 (en) | 2015-11-10 | 2016-11-03 | Topical formulations and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI3373976T3 true FI3373976T3 (fi) | 2024-03-25 |
Family
ID=58695926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FIEP16864797.2T FI3373976T3 (fi) | 2015-11-10 | 2016-11-03 | Topikaalisia formulaatioita ja niiden käyttöjä |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20190231885A1 (https=) |
| EP (2) | EP3373976B1 (https=) |
| JP (2) | JP7793283B2 (https=) |
| AU (1) | AU2016351588A1 (https=) |
| DK (1) | DK3373976T3 (https=) |
| ES (1) | ES2974821T3 (https=) |
| FI (1) | FI3373976T3 (https=) |
| PL (1) | PL3373976T3 (https=) |
| PT (1) | PT3373976T (https=) |
| WO (1) | WO2017083167A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2887923T3 (pl) | 2012-08-24 | 2023-08-14 | Sun Pharmaceutical Industries Limited | Preparat okulistyczny polioksylipidu lub polioksylowego kwasu tłuszczowego i leczenie chorób oczu |
| EP3373976B1 (en) | 2015-11-10 | 2024-01-03 | Sun Pharmaceutical Industries Limited | Topical formulations and uses thereof |
| US10918694B2 (en) * | 2016-02-29 | 2021-02-16 | Sun Pharma Global Fze | Topical cyclosporine-containing formulations and uses thereof |
| WO2021224901A2 (en) * | 2021-08-20 | 2021-11-11 | Sun Pharmaceutical Industries Limited | Stable cyclosporine ophthalmic formulation and manufacturing process thereof |
Family Cites Families (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69307505T2 (de) | 1992-05-13 | 1997-07-24 | Sandoz-Patent-Gmbh, 79539 Loerrach | Opthalmische zusammensetzungen enthaltend ein cyclosporin |
| NZ247516A (en) | 1993-04-28 | 1995-02-24 | Bernard Charles Sherman | Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant |
| US5484597A (en) * | 1993-07-30 | 1996-01-16 | Chesebrough-Pond's Usa Co. | Clear hydroalcholic cosmetic microemulsions |
| NZ280689A (en) | 1995-12-15 | 1997-08-22 | Bernard Charles Sherma Sherman | Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol |
| MX9701946A (es) | 1997-03-14 | 1998-04-30 | Arturo Jimenez Bayardo | Solucion oftalmica transportadora. |
| US7678836B2 (en) | 1999-11-04 | 2010-03-16 | Fxs Ventures, Llc | Method for rendering a contact lens wettable |
| US7732404B2 (en) | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
| JP4932116B2 (ja) | 2000-02-16 | 2012-05-16 | ザ・ブリガーム・アンド・ウーメンズ・ホスピタル・インコーポレーテッド | アスピリン誘発脂質メディエータ |
| US20030176356A1 (en) | 2001-04-24 | 2003-09-18 | University Of North Texas Health Science Center | Endothelin antagonists and endothelin-converting enzyme inhibitors for the treatment of glaucoma |
| HRP20040354B1 (en) | 2001-10-19 | 2012-10-31 | Isotechnika Inc. | Novel cyclosporin analog microemulsion preconcentrates |
| AU2002365167A1 (en) | 2001-12-18 | 2003-07-09 | The Brigham And Women's Hospital | Inhibition or prevention of infection by bacteria with epa, dha or analogs |
| US7582785B2 (en) | 2002-04-01 | 2009-09-01 | University Of Southern California | Trihydroxy polyunsaturated eicosanoid derivatives |
| WO2003084305A2 (en) | 2002-04-01 | 2003-10-16 | University Of Southern California | Trihydroxy polyunsaturated eicosanoids |
| DE60330154D1 (de) | 2002-08-12 | 2009-12-31 | Brigham & Womens Hospital | Resolvine: biotemplate zur durchführung therapeutischer anwendungen |
| US7759395B2 (en) | 2002-08-12 | 2010-07-20 | The Brigham And Women's Hospital, Inc. | Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma |
| WO2004069181A2 (en) | 2003-02-03 | 2004-08-19 | Pharmacia Corporation | Composition for the treatment of intraocular pressure |
| JP2004238346A (ja) | 2003-02-07 | 2004-08-26 | Shiono Chemical Co Ltd | トラニラストの安定な水溶液製剤 |
| WO2004078143A2 (en) | 2003-03-05 | 2004-09-16 | The Brigham And Women's Hospital Inc. | Methods for identification and uses of anti-inflammatory receptors for eicosapentaenoic acid analogs |
| WO2004096261A1 (es) | 2003-05-02 | 2004-11-11 | Arturo Jimenez Bayardo | Metodo para preparar una solucion acuosa de ciclosporina-a y solucion acuosa resultante |
| US7087237B2 (en) | 2003-09-19 | 2006-08-08 | Advanced Ocular Systems Limited | Ocular solutions |
| US20050238589A1 (en) | 2004-04-14 | 2005-10-27 | Van Dyke Thomas E | Methods and compositions for preventing or treating periodontal diseases |
| DE602004017477D1 (de) | 2004-11-09 | 2008-12-11 | Novagali Pharma Sa | Öl-in-Wasser-Emulsion mit niedriger Konzentration des kationischen Mittels und positivem Zetapotential |
| WO2006055965A2 (en) | 2004-11-19 | 2006-05-26 | Martek Biosciences Corporation | Oxylipins from long chain polyunsaturated fatty acids and methods of making and using the same |
| US20090209599A1 (en) | 2005-06-09 | 2009-08-20 | Yoko Endo | Eye drop containing roflumilast |
| EP1890677A4 (en) | 2005-06-16 | 2013-01-30 | Myriad Genetics Inc | PHARMACEUTICAL COMPOSITIONS AND THEIR USE |
| US20070015691A1 (en) | 2005-07-13 | 2007-01-18 | Allergan, Inc. | Cyclosporin compositions |
| AU2006270041B2 (en) | 2005-07-18 | 2011-08-18 | Minu, Llc | Enhanced ocular neuroprotection/neurostimulation |
| EP1983977A4 (en) | 2006-01-31 | 2011-11-30 | Martek Biosciences Corp | OXYLIPINES FROM STEARIDONIC ACID AND GAMMA-LINOLIC ACID AND METHOD FOR THE PRODUCTION AND USE THEREOF |
| US10137083B2 (en) | 2006-03-07 | 2018-11-27 | SGN Nanopharma Inc | Ophthalmic preparations |
| CA2650422A1 (en) | 2006-04-24 | 2007-11-08 | Nanocarrier Co., Ltd. | Process for producing polymer micelles encapsulating low molecular weight drugs |
| WO2007136134A1 (ja) | 2006-05-23 | 2007-11-29 | Nanocarrier Co., Ltd. | 疎水性薬物内包ポリマーミセルの製造方法 |
| CN101489574A (zh) | 2006-07-18 | 2009-07-22 | 那野伽利阿株式会社 | 内包生理活性多肽或蛋白质的高分子聚合物胶束及其制造方法 |
| EP2120920A4 (en) | 2007-02-20 | 2011-06-15 | Martek Biosciences Corp | OXYLIPINES OF LONG-CHAIN MULTIPLE-UNSATURATED FATTY ACIDS AND METHOD FOR THEIR PREPARATION AND USE |
| US20100310462A1 (en) | 2007-04-18 | 2010-12-09 | Biochromix Ab | Binding of pathological forms of proteins using conjugated polyelectrolytes |
| US8512687B2 (en) | 2007-07-09 | 2013-08-20 | Novagali Pharma Sa | Oil in water emulsion comprising NSAIDs and quaternary ammonium halides |
| EP2193795B1 (en) | 2007-08-29 | 2014-10-01 | Wakamoto Pharmaceutical Co., Ltd. | Latanoprost-containing aqueous pharmaceutical composition |
| MX2007011165A (es) | 2007-09-12 | 2009-03-11 | Arturo Jimenez Bayardo | Composición farmacéutica estable de timolol, dorzolamida y brimonidina. |
| ES2667945T3 (es) | 2007-10-08 | 2018-05-16 | Aurinia Pharmaceuticals Inc. | Composiciones oftálmicas que comprenden inhibidores de calcineurina o Inhibidores de mTOR |
| JP2011508776A (ja) | 2008-01-04 | 2011-03-17 | アルコン ファーマシューティカルズ リミテッド | 安定な水性シクロスポリン組成物 |
| TWI544927B (zh) | 2008-03-17 | 2016-08-11 | 愛爾康研究有限公司 | 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物 |
| EP2278953B1 (en) | 2008-05-28 | 2016-05-04 | Alcon Research, Ltd | Self-preserved emulsions |
| EP2127638A1 (en) | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Method and composition for treating ocular hypertension and glaucoma |
| AP2012006053A0 (en) | 2009-06-02 | 2012-02-29 | Brian Charles Keller | Pure peg-lipid conjugates. |
| EP2440185B1 (en) | 2009-06-09 | 2015-04-08 | Aurinia Pharmaceuticals Inc. | Topical drug delivery systems for ophthalmic use |
| EP2478906A4 (en) | 2009-09-17 | 2013-02-20 | Senju Pharma Co | AQUEOUS OPHTHALMIC DROPS THAT CONTAIN LATANOPROST, AND A METHOD OF INHIBITING ADSORPTION OF LATANOPROST ON A RESIN |
| US8637569B2 (en) | 2009-10-22 | 2014-01-28 | Api Genesis, Llc | Methods of increasing solubility of poorly soluble compounds and methods of making and using formulations of such compounds |
| EP2538965B1 (en) | 2010-02-25 | 2017-04-12 | Schepens Eye Research Institute | Therapeutic compositions for the treatment of dry eye disease |
| WO2011138801A1 (en) | 2010-05-07 | 2011-11-10 | Sun Pharma Advanced Research Company Ltd. | Novel ophthalmic compositions |
| US20130065888A1 (en) | 2011-08-15 | 2013-03-14 | Biserka Cetina-Cizmek | Ophthalmic formulations and processes for their preparation |
| US9278132B2 (en) | 2012-02-13 | 2016-03-08 | Bausch & Lomb Incorporated | Ophthalmic pharmaceutical compositions and methods of making and using same |
| KR101211902B1 (ko) | 2012-04-30 | 2012-12-13 | 주식회사 휴온스 | 사이클로스포린 함유 무자극성 나노에멀젼 안약 조성물 |
| MX2014013714A (es) | 2012-05-11 | 2015-08-10 | Cipla Ltd | Composicion farmaceutica. |
| PL2887923T3 (pl) * | 2012-08-24 | 2023-08-14 | Sun Pharmaceutical Industries Limited | Preparat okulistyczny polioksylipidu lub polioksylowego kwasu tłuszczowego i leczenie chorób oczu |
| WO2014126997A1 (en) | 2013-02-13 | 2014-08-21 | The Research Foundation For The State University Of New York | Glaucoma treatment |
| AU2015264181A1 (en) | 2014-05-23 | 2016-12-01 | Ocular Technologies Sarl | Topical formulations and uses thereof |
| US20150352176A1 (en) | 2014-06-06 | 2015-12-10 | Newport Research, Inc. | Oil-free and fat-free aqueous suspensions of cyclosporin |
| US9421199B2 (en) | 2014-06-24 | 2016-08-23 | Sydnexis, Inc. | Ophthalmic composition |
| US20180133217A1 (en) | 2015-05-04 | 2018-05-17 | Ocular Technologies Sarl | Topical formulations and uses thereof |
| EP3373976B1 (en) | 2015-11-10 | 2024-01-03 | Sun Pharmaceutical Industries Limited | Topical formulations and uses thereof |
| EP3373924A4 (en) | 2015-11-12 | 2019-06-19 | Sun Pharma Global FZE | Topical formulations and uses thereof |
| US10918694B2 (en) | 2016-02-29 | 2021-02-16 | Sun Pharma Global Fze | Topical cyclosporine-containing formulations and uses thereof |
| WO2017152129A2 (en) | 2016-03-03 | 2017-09-08 | Ocular Technologies Sarl | Treatment of glaucoma and/or retinal diseases and formulations useful therefore |
-
2016
- 2016-11-03 EP EP16864797.2A patent/EP3373976B1/en active Active
- 2016-11-03 WO PCT/US2016/060391 patent/WO2017083167A1/en not_active Ceased
- 2016-11-03 PT PT168647972T patent/PT3373976T/pt unknown
- 2016-11-03 US US15/772,779 patent/US20190231885A1/en not_active Abandoned
- 2016-11-03 PL PL16864797.2T patent/PL3373976T3/pl unknown
- 2016-11-03 EP EP23219654.3A patent/EP4364810A3/en active Pending
- 2016-11-03 FI FIEP16864797.2T patent/FI3373976T3/fi active
- 2016-11-03 ES ES16864797T patent/ES2974821T3/es active Active
- 2016-11-03 DK DK16864797.2T patent/DK3373976T3/da active
- 2016-11-03 JP JP2018543272A patent/JP7793283B2/ja active Active
- 2016-11-03 AU AU2016351588A patent/AU2016351588A1/en not_active Abandoned
-
2021
- 2021-03-12 US US17/200,454 patent/US12053528B2/en active Active
-
2022
- 2022-11-04 JP JP2022177207A patent/JP7669326B2/ja active Active
-
2024
- 2024-07-02 US US18/762,112 patent/US20240358840A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3373976A4 (en) | 2019-05-22 |
| WO2017083167A1 (en) | 2017-05-18 |
| AU2016351588A1 (en) | 2018-05-24 |
| EP3373976A1 (en) | 2018-09-19 |
| PT3373976T (pt) | 2024-04-02 |
| EP4364810A3 (en) | 2024-07-24 |
| JP2023012533A (ja) | 2023-01-25 |
| EP3373976B1 (en) | 2024-01-03 |
| JP7793283B2 (ja) | 2026-01-05 |
| EP4364810A2 (en) | 2024-05-08 |
| DK3373976T3 (da) | 2024-04-02 |
| PL3373976T3 (pl) | 2024-06-24 |
| US20240358840A1 (en) | 2024-10-31 |
| JP2018532809A (ja) | 2018-11-08 |
| ES2974821T3 (es) | 2024-07-01 |
| US20210268114A1 (en) | 2021-09-02 |
| US12053528B2 (en) | 2024-08-06 |
| JP7669326B2 (ja) | 2025-04-28 |
| US20190231885A1 (en) | 2019-08-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20230559T1 (hr) | Oftalmička formulacija polioksil lipida ili polioksil masne kiseline i tretman očnih stanja | |
| CL2018003178A1 (es) | Composición farmacéutica | |
| FI3373976T3 (fi) | Topikaalisia formulaatioita ja niiden käyttöjä | |
| AR086115A1 (es) | Formulaciones parenterales mejoradas de agentes farmaceuticos lipofilos y los metodos para la preparacion y el uso de las mismas | |
| BR112015019657A2 (pt) | composições tópicas e métodos de uso das mesmas | |
| MD20140102A2 (ro) | Compoziţii topice cu conţinut de fipronil şi permetrină şi metode de utilizare a lor | |
| CO6311052A2 (es) | Una microemulsion que comprende un ingrediente activo, un solvente y un surfactante no ionico y proceso para su preparación | |
| BRPI0508933A (pt) | composições para entrega tópica | |
| BR112016025126A2 (pt) | formulação líquida compreendendo composto neutralizante de gm-csf | |
| RU2017109903A (ru) | Композиции диклофенака натрия для местного применения | |
| WO2015081904A3 (en) | Polyurethaneurea solutions for compositions with active ingredients or fragrances | |
| CO2021016449A2 (es) | Composiciones terapéuticas estables en solventes polares aproticos y métodos de fabricación de las mismas | |
| MX390004B (es) | Formulaciones y tratamientos topicos. | |
| NI201900063A (es) | Amidas aromáticas de ácido carboxílico | |
| JP2015504860A5 (https=) | ||
| BR112017017643A2 (pt) | formulação farmacêutica tópica | |
| AR085273A1 (es) | Formulacion liquida libre de propelente que comprende una droga antimuscarinica | |
| MX2016014256A (es) | Formulaciones y metodos para el suministro vaginal de antiprogestinas. | |
| AR086448A1 (es) | Composicion farmaceutica que comprende drotaverina | |
| JP2010132607A (ja) | アトピー性皮膚炎治療用軟膏剤 | |
| RU2012135798A (ru) | Фармацевтическая композиция для лечения зуда кожи | |
| JP6503627B2 (ja) | 医薬液体組成物 | |
| JP6503626B2 (ja) | 医薬組成物 | |
| MX2022004368A (es) | Formulacion de mezclas insecticidas que comprenden disolventes de eter de glicol. | |
| RU2015132458A (ru) | Пленочное покрытие препаративных форм, содержащих биологически активные вещества, суспензия для его формирования и способ его нанесения |