FI3197431T3 - Vaahtoa muodostavia koostumuksia ja menetelmiä aktiivisen agenssin toimittamiseksi kehon onteloon - Google Patents
Vaahtoa muodostavia koostumuksia ja menetelmiä aktiivisen agenssin toimittamiseksi kehon onteloon Download PDFInfo
- Publication number
- FI3197431T3 FI3197431T3 FIEP15843723.6T FI15843723T FI3197431T3 FI 3197431 T3 FI3197431 T3 FI 3197431T3 FI 15843723 T FI15843723 T FI 15843723T FI 3197431 T3 FI3197431 T3 FI 3197431T3
- Authority
- FI
- Finland
- Prior art keywords
- foam
- forming composition
- composition according
- body cavity
- active agent
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 20
- 239000013543 active substance Substances 0.000 title claims 4
- 150000002632 lipids Chemical class 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 5
- 239000013078 crystal Substances 0.000 claims 5
- 239000006260 foam Substances 0.000 claims 5
- 239000007787 solid Substances 0.000 claims 5
- 239000003380 propellant Substances 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims 2
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 claims 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims 2
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 claims 2
- NNPPMTNAJDCUHE-UHFFFAOYSA-N isobutane Chemical compound CC(C)C NNPPMTNAJDCUHE-UHFFFAOYSA-N 0.000 claims 2
- 230000008018 melting Effects 0.000 claims 2
- 238000002844 melting Methods 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 1
- XOBKSJJDNFUZPF-UHFFFAOYSA-N Methoxyethane Chemical compound CCOC XOBKSJJDNFUZPF-UHFFFAOYSA-N 0.000 claims 1
- 206010046543 Urinary incontinence Diseases 0.000 claims 1
- 230000001078 anti-cholinergic effect Effects 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 210000000436 anus Anatomy 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 239000001273 butane Substances 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 229910002092 carbon dioxide Inorganic materials 0.000 claims 1
- 239000001569 carbon dioxide Substances 0.000 claims 1
- 238000005187 foaming Methods 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 239000001282 iso-butane Substances 0.000 claims 1
- -1 isopropane Chemical compound 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 claims 1
- IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 claims 1
- OFBQJSOFQDEBGM-UHFFFAOYSA-N n-pentane Natural products CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 210000001331 nose Anatomy 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000001294 propane Substances 0.000 claims 1
- 210000003708 urethra Anatomy 0.000 claims 1
- 210000001215 vagina Anatomy 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/122—Foams; Dry foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/40—Peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/124—Aerosols; Foams characterised by the propellant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Inorganic Chemistry (AREA)
- Otolaryngology (AREA)
- Gynecology & Obstetrics (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462055001P | 2014-09-25 | 2014-09-25 | |
| PCT/SE2015/051011 WO2016048230A1 (en) | 2014-09-25 | 2015-09-25 | Foam-forming compositions and methods for delivering an active agent to a body cavity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI3197431T3 true FI3197431T3 (fi) | 2023-05-11 |
Family
ID=55581573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FIEP15843723.6T FI3197431T3 (fi) | 2014-09-25 | 2015-09-25 | Vaahtoa muodostavia koostumuksia ja menetelmiä aktiivisen agenssin toimittamiseksi kehon onteloon |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9895311B2 (enExample) |
| EP (2) | EP3197431B1 (enExample) |
| JP (1) | JP6659674B2 (enExample) |
| KR (1) | KR102569954B1 (enExample) |
| CN (1) | CN106687109B (enExample) |
| AU (1) | AU2015322112B2 (enExample) |
| BR (1) | BR112017006154B1 (enExample) |
| CA (1) | CA2959717C (enExample) |
| DK (1) | DK3197431T3 (enExample) |
| ES (1) | ES2946510T3 (enExample) |
| FI (1) | FI3197431T3 (enExample) |
| HU (1) | HUE062224T2 (enExample) |
| PL (1) | PL3197431T3 (enExample) |
| PT (1) | PT3197431T (enExample) |
| RU (1) | RU2710019C2 (enExample) |
| WO (1) | WO2016048230A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9895311B2 (en) * | 2014-09-25 | 2018-02-20 | Pharmiva Ab | Foam-forming compositions and methods for delivering an active to a body cavity |
| US20200069630A1 (en) * | 2016-07-11 | 2020-03-05 | Hennipen Life Sciences, Llc | Compositions for sexually transmitted diseases |
| CN110785163B (zh) * | 2017-05-23 | 2023-09-05 | 法尔米瓦股份公司 | 用于递送活性剂至体腔的泡沫形成组合物 |
| CA3204971A1 (en) | 2021-01-27 | 2022-08-04 | Ake Lindal | Composition for use in degradation of biofilm or prevention of biofilm formation |
| US20230000795A1 (en) * | 2021-06-11 | 2023-01-05 | Ankh Life Sciences Limited | Lipid crystalline compositions with enhanced stability for topical delivery of active agent combinations |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4684479A (en) | 1985-08-14 | 1987-08-04 | Arrigo Joseph S D | Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures |
| SE454397B (sv) * | 1985-12-20 | 1988-05-02 | Biogram Ab | Stabiliserad vattenbaserad antimikrobiell veteperoxidkomposition, forfarande for framstellning derav samt anvendning derav som antimikrobiell spendoppningskomposition for mjolkproducerande djur |
| JPH06279228A (ja) | 1993-03-30 | 1994-10-04 | Kao Corp | 発泡性組成物 |
| US5576016A (en) * | 1993-05-18 | 1996-11-19 | Pharmos Corporation | Solid fat nanoemulsions as drug delivery vehicles |
| JPH07197083A (ja) | 1993-12-28 | 1995-08-01 | Kao Corp | 洗浄剤組成物 |
| US5741525A (en) | 1995-10-24 | 1998-04-21 | Marshall University Research Corporation | Vaginal pharmaceutical hydrogen peroxide composition |
| US5778886A (en) * | 1996-02-27 | 1998-07-14 | Shihata; Alfred | Vaginal compositions combining a spermicidal agent and a peroxygen compound |
| US6156294A (en) | 1999-11-28 | 2000-12-05 | Scientific Development And Research, Inc. | Composition and method for treatment of otitis media |
| US20020031556A1 (en) * | 2000-07-21 | 2002-03-14 | Lindahl Ake R. | Stabilized hydrogen peroxide composition and method of making a stabilized hydrogen peroxide composition |
| US7709026B2 (en) | 2001-10-29 | 2010-05-04 | Columbia Laboratories, Inc. | Low concentration of peroxide for treating or preventing vaginal infections |
| US20070292355A1 (en) * | 2002-10-25 | 2007-12-20 | Foamix Ltd. | Anti-infection augmentation foamable compositions and kit and uses thereof |
| EP1592420B1 (en) | 2003-01-24 | 2014-01-01 | Stiefel Research Australia Pty Ltd | Clindamycin phosphate foam |
| US8193244B1 (en) | 2008-05-29 | 2012-06-05 | Nevada Naturals, Inc. | Antimicrobial agents |
| US20040197270A1 (en) * | 2003-04-01 | 2004-10-07 | Mundschenk David D. | Topical formulations and delivery systems |
| MXPA06002163A (es) * | 2003-08-25 | 2006-05-22 | Foamix Ltd | Espuma farmaceutica de penetracion. |
| US20050058673A1 (en) | 2003-09-09 | 2005-03-17 | 3M Innovative Properties Company | Antimicrobial compositions and methods |
| ZA200507019B (en) | 2004-04-28 | 2008-02-27 | Foamix Ltd | Body cavity foams |
| CN101137359B (zh) | 2005-03-10 | 2011-01-12 | 3M创新有限公司 | 治疗耳感染的方法 |
| US20070299043A1 (en) * | 2005-10-03 | 2007-12-27 | Hunter William L | Anti-scarring drug combinations and use thereof |
| JP2009522003A (ja) * | 2005-12-29 | 2009-06-11 | スリーエム イノベイティブ プロパティズ カンパニー | 発泡性歯科用組成物及び方法 |
| WO2008075207A2 (en) | 2006-04-04 | 2008-06-26 | Foamix Ltd. | Anti-infection augmentation foamable compositions and kit and uses thereof |
| WO2008110872A2 (en) * | 2006-06-23 | 2008-09-18 | Foamix Ltd. | Foamable compositions and kits comprising one or more of a channel agent, a cholinergic agent, a nitric oxide donor, and related agents and their uses |
| RU2459620C2 (ru) * | 2007-03-30 | 2012-08-27 | Лаккуре Аб | Применение олигомеров молочной кислоты в лечении гинекологических расстройств |
| PL2020221T3 (pl) * | 2007-06-19 | 2012-07-31 | Neubourg Skin Care Gmbh & Co Kg | Kremy DMS (Derma Membrane Structure) w postaci pianki |
| US20090239954A1 (en) * | 2008-03-19 | 2009-09-24 | Collins Gary L | Phosphate buffered ophthalmic solutions displaying improved efficacy |
| WO2011039637A2 (en) | 2009-10-02 | 2011-04-07 | Foamix Ltd. | Surfactant-free water-free foamable compositions, breakable foams and gels and their uses |
| US8414868B2 (en) * | 2010-02-04 | 2013-04-09 | Ultradent Products, Inc. | In situ foamable dental bleaching compositions and methods, systems and kits for bleaching teeth using such compositions |
| BR112015027026A8 (pt) * | 2013-04-26 | 2018-01-30 | Bioglan Ab | composição para uso na redução da formação de casca e na promoção da cicatrização |
| US9895311B2 (en) * | 2014-09-25 | 2018-02-20 | Pharmiva Ab | Foam-forming compositions and methods for delivering an active to a body cavity |
-
2015
- 2015-09-24 US US14/864,083 patent/US9895311B2/en active Active
- 2015-09-25 AU AU2015322112A patent/AU2015322112B2/en not_active Ceased
- 2015-09-25 PT PT158437236T patent/PT3197431T/pt unknown
- 2015-09-25 ES ES15843723T patent/ES2946510T3/es active Active
- 2015-09-25 WO PCT/SE2015/051011 patent/WO2016048230A1/en not_active Ceased
- 2015-09-25 HU HUE15843723A patent/HUE062224T2/hu unknown
- 2015-09-25 JP JP2017516659A patent/JP6659674B2/ja not_active Expired - Fee Related
- 2015-09-25 PL PL15843723.6T patent/PL3197431T3/pl unknown
- 2015-09-25 CN CN201580051590.3A patent/CN106687109B/zh not_active Expired - Fee Related
- 2015-09-25 DK DK15843723.6T patent/DK3197431T3/da active
- 2015-09-25 KR KR1020177010958A patent/KR102569954B1/ko active Active
- 2015-09-25 EP EP15843723.6A patent/EP3197431B1/en active Active
- 2015-09-25 EP EP23156021.0A patent/EP4218803A3/en not_active Withdrawn
- 2015-09-25 FI FIEP15843723.6T patent/FI3197431T3/fi active
- 2015-09-25 CA CA2959717A patent/CA2959717C/en active Active
- 2015-09-25 BR BR112017006154-6A patent/BR112017006154B1/pt not_active IP Right Cessation
- 2015-09-25 RU RU2017112055A patent/RU2710019C2/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| DK3197431T3 (da) | 2023-06-06 |
| CN106687109B (zh) | 2020-10-23 |
| US9895311B2 (en) | 2018-02-20 |
| RU2017112055A (ru) | 2018-10-25 |
| WO2016048230A1 (en) | 2016-03-31 |
| KR102569954B1 (ko) | 2023-08-22 |
| EP3197431A1 (en) | 2017-08-02 |
| AU2015322112B2 (en) | 2020-10-22 |
| PT3197431T (pt) | 2023-05-10 |
| RU2710019C2 (ru) | 2019-12-24 |
| CA2959717A1 (en) | 2016-03-31 |
| BR112017006154A2 (en) | 2018-02-06 |
| ES2946510T3 (es) | 2023-07-20 |
| HUE062224T2 (hu) | 2023-10-28 |
| EP3197431B1 (en) | 2023-03-08 |
| AU2015322112A1 (en) | 2017-03-30 |
| EP4218803A2 (en) | 2023-08-02 |
| JP6659674B2 (ja) | 2020-03-04 |
| EP4218803A3 (en) | 2023-11-01 |
| PL3197431T3 (pl) | 2023-06-19 |
| BR112017006154B1 (pt) | 2024-01-23 |
| CN106687109A (zh) | 2017-05-17 |
| EP3197431A4 (en) | 2018-04-04 |
| KR20170059000A (ko) | 2017-05-29 |
| RU2017112055A3 (enExample) | 2019-03-25 |
| CA2959717C (en) | 2022-10-18 |
| JP2017529377A (ja) | 2017-10-05 |
| US20160089333A1 (en) | 2016-03-31 |
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