FI20060188A - Modifioidut IL-4-muteiinin reseptorin antagonistit - Google Patents
Modifioidut IL-4-muteiinin reseptorin antagonistit Download PDFInfo
- Publication number
- FI20060188A FI20060188A FI20060188A FI20060188A FI20060188A FI 20060188 A FI20060188 A FI 20060188A FI 20060188 A FI20060188 A FI 20060188A FI 20060188 A FI20060188 A FI 20060188A FI 20060188 A FI20060188 A FI 20060188A
- Authority
- FI
- Finland
- Prior art keywords
- modified
- receptor antagonists
- mutein receptor
- mutein
- antagonists
- Prior art date
Links
- 108090000978 Interleukin-4 Proteins 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2026—IL-4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/45—Toxoplasma
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5406—IL-4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/247—IL-4
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Marine Sciences & Fisheries (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49890603P | 2003-08-29 | 2003-08-29 | |
US52822803P | 2003-12-09 | 2003-12-09 | |
US53018203P | 2003-12-17 | 2003-12-17 | |
US10/820,559 US7404957B2 (en) | 2003-08-29 | 2004-04-08 | Modified IL-4 mutein receptor antagonists |
PCT/US2004/023310 WO2005023860A2 (en) | 2003-08-29 | 2004-07-20 | Modified il-4 mutein receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
FI20060188A true FI20060188A (fi) | 2006-02-24 |
Family
ID=34280052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI20060188A FI20060188A (fi) | 2003-08-29 | 2006-02-24 | Modifioidut IL-4-muteiinin reseptorin antagonistit |
Country Status (15)
Country | Link |
---|---|
US (1) | US7404957B2 (fi) |
EP (1) | EP1660529A2 (fi) |
JP (1) | JP4774368B2 (fi) |
KR (1) | KR20070008505A (fi) |
AU (1) | AU2004270638B2 (fi) |
BR (1) | BRPI0413869A (fi) |
CA (1) | CA2536586A1 (fi) |
CZ (1) | CZ2006206A3 (fi) |
DK (1) | DK200600449A (fi) |
ES (1) | ES2315146A1 (fi) |
FI (1) | FI20060188A (fi) |
IL (1) | IL173746A0 (fi) |
IS (1) | IS8315A (fi) |
MX (1) | MXPA06002285A (fi) |
WO (1) | WO2005023860A2 (fi) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7785580B2 (en) * | 2003-08-29 | 2010-08-31 | Aerovance, Inc. | Modified IL-4 mutein receptor antagonists |
KR101241434B1 (ko) * | 2004-09-10 | 2013-03-12 | 파마오리진 에이피에스 | 국소 기관, 기관지 또는 폐포의 출혈 또는 객혈의 치료방법 |
US20070009479A1 (en) * | 2005-06-17 | 2007-01-11 | Aerovance, Inc. | Methods for treating dermatitis using mutant human IL-4 compositions |
KR101566393B1 (ko) * | 2005-08-03 | 2015-11-05 | 이뮤노젠 아이엔씨 | 면역접합체 제형 |
JP2009525267A (ja) * | 2006-01-11 | 2009-07-09 | アエロヴァンス インコーポレイティッド | ヒトおよび非ヒト霊長類において喘息を処置するための方法および組成物 |
CA2656135A1 (en) * | 2006-07-06 | 2008-01-10 | Apogenix Gmbh | Human il-4 muteins in cancer therapy |
EA201070129A1 (ru) * | 2007-07-11 | 2010-10-29 | Аэрованс, Инк. | Фармацевтический сухой порошкообразный аэрозольный состав, включающий полипептид, и способ его приготовления |
JP2012520326A (ja) * | 2009-03-13 | 2012-09-06 | アエロヴァンス インコーポレイティッド | 組換えタンパク質の再生法 |
WO2011154420A2 (en) | 2010-06-08 | 2011-12-15 | Pieris Ag | Tear lipocalin muteins binding il-4 r alpha |
WO2015000585A1 (en) | 2013-07-02 | 2015-01-08 | Walter Sebald | Muteins of cytokines of the gamma-chain receptor family conjugated to a non-protein group |
RU2758092C1 (ru) * | 2018-02-01 | 2021-10-26 | Бэйцзин Кавин Текнолоджи Шеа-Холдинг Ко., Лтд. | АНТИТЕЛО К IL-4Rα И ЕГО ПРИМЕНЕНИЕ |
EP3553078A1 (en) * | 2018-04-11 | 2019-10-16 | Julius-Maximilians-Universität Würzburg | Glyco-engineered interleukin-4 based antagonists |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4423131A1 (de) * | 1994-07-01 | 1996-01-04 | Bayer Ag | Neue hIL-4-Mutantenproteine als Antagonisten oder partielle Agonisten des humanen Interleukin 4 |
GB9415379D0 (en) * | 1994-07-29 | 1994-09-21 | Smithkline Beecham Plc | Novel compounds |
US5986059A (en) * | 1996-06-14 | 1999-11-16 | Bayer Corporation | T-cell selective interleukin-4 agonists |
US6028176A (en) | 1996-07-19 | 2000-02-22 | Bayer Corporation | High-affinity interleukin-4 muteins |
MY124565A (en) | 1996-07-19 | 2006-06-30 | Bayer Corp | High-affinity interleukin-4-muteins |
DE69838552T2 (de) * | 1997-07-14 | 2008-05-21 | Bolder Biotechnology, Inc., Louisville | Derivate des wachstumshormons und verwandte proteine |
US9303613B2 (en) | 2012-02-24 | 2016-04-05 | Ford Global Technologies, Llc | Control of vehicle electrical loads during engine auto stop event |
-
2004
- 2004-04-08 US US10/820,559 patent/US7404957B2/en not_active Expired - Fee Related
- 2004-07-20 EP EP04778687A patent/EP1660529A2/en not_active Withdrawn
- 2004-07-20 WO PCT/US2004/023310 patent/WO2005023860A2/en not_active Application Discontinuation
- 2004-07-20 AU AU2004270638A patent/AU2004270638B2/en not_active Ceased
- 2004-07-20 KR KR1020067004147A patent/KR20070008505A/ko not_active Application Discontinuation
- 2004-07-20 CZ CZ20060206A patent/CZ2006206A3/cs unknown
- 2004-07-20 MX MXPA06002285A patent/MXPA06002285A/es active IP Right Grant
- 2004-07-20 CA CA002536586A patent/CA2536586A1/en not_active Abandoned
- 2004-07-20 BR BRPI0413869-4A patent/BRPI0413869A/pt not_active IP Right Cessation
- 2004-07-20 JP JP2006524657A patent/JP4774368B2/ja not_active Expired - Fee Related
- 2004-07-20 ES ES200650017A patent/ES2315146A1/es active Pending
-
2006
- 2006-02-15 IL IL173746A patent/IL173746A0/en unknown
- 2006-02-20 IS IS8315A patent/IS8315A/is unknown
- 2006-02-24 FI FI20060188A patent/FI20060188A/fi unknown
- 2006-03-29 DK DK200600449A patent/DK200600449A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2004270638A2 (en) | 2005-03-17 |
US20050059590A1 (en) | 2005-03-17 |
IL173746A0 (en) | 2006-07-05 |
IS8315A (is) | 2006-02-20 |
AU2004270638B2 (en) | 2010-10-07 |
ES2315146A1 (es) | 2009-03-16 |
CZ2006206A3 (cs) | 2007-01-10 |
US7404957B2 (en) | 2008-07-29 |
JP4774368B2 (ja) | 2011-09-14 |
BRPI0413869A (pt) | 2006-10-24 |
DK200600449A (da) | 2006-03-29 |
KR20070008505A (ko) | 2007-01-17 |
CA2536586A1 (en) | 2005-03-17 |
AU2004270638A1 (en) | 2005-03-17 |
WO2005023860A2 (en) | 2005-03-17 |
WO2005023860A3 (en) | 2005-06-23 |
EP1660529A2 (en) | 2006-05-31 |
JP2007526757A (ja) | 2007-09-20 |
MXPA06002285A (es) | 2007-03-15 |
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