FI118294B - Diklofenak-na innehållande depottablett - Google Patents

Diklofenak-na innehållande depottablett Download PDF

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Publication number
FI118294B
FI118294B FI963567A FI963567A FI118294B FI 118294 B FI118294 B FI 118294B FI 963567 A FI963567 A FI 963567A FI 963567 A FI963567 A FI 963567A FI 118294 B FI118294 B FI 118294B
Authority
FI
Finland
Prior art keywords
tablet
diclofenac
methylhydroxypropylcellulose
release
prolonged
Prior art date
Application number
FI963567A
Other languages
English (en)
Finnish (fi)
Other versions
FI963567A (sv
FI963567A0 (sv
Inventor
Wilfried Fischer
Karin Klokkers
Original Assignee
Hexal Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6512563&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI118294(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hexal Ag filed Critical Hexal Ag
Publication of FI963567A publication Critical patent/FI963567A/sv
Publication of FI963567A0 publication Critical patent/FI963567A0/sv
Application granted granted Critical
Publication of FI118294B publication Critical patent/FI118294B/sv

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (3)

1. Depottablett, som innehäller som aktivt ämne diklofenak-Na och som retarderingsmedel metylhydroxipro- 5 pylcellulosa samt konventionella hjälpmedel, känne-tecknad av att därav, att den omfattar (a) en tablettdel (retarderad del), som innehäller diklofenak-Na och metylhydroxipropylcellulosa och där för-hällandet mellan metylhydroxipropylcellulosa och diklo- 10 fenak-Na är minst 0,3, och (b) en andra tablettdel (initieringsdel), som innehäller diklofenak-Na och metylhydroxipropylcellulosa och där förhällandet mellan metylhydroxipropylcellulosa och diklofenak-Na är 0,23 - under 0,3, 15 varvid vardera delen innehäller konventionella hjälpmedel, och varvid nämnda depottablett kan erhällas sä, att tablettdelarna (a) och (b) framställs separat och därefter kombineras till färdig tablett.
2. Depottablett enligt patentkrav 1, kän- 20 netecknad av att delarna (a) och (b) sammanpressas.
3. Depottablett enligt patentkrav 2, kän- i\t netecknad av att delarna (a) och (b) sammanpressas . .·. till en flerskiktig tablett. • · * ··· · • · · • · * ··* · ·· · • · * • * • · • · · • · · ··· ··· • « * * · « • mm m m m ·· • ··· 9 · m m • mm m mm m * • ·* m mmm m m • * ··· m mm m m m mm m m m m
FI963567A 1994-03-11 1996-09-10 Diklofenak-na innehållande depottablett FI118294B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4408326 1994-03-11
DE4408326A DE4408326A1 (de) 1994-03-11 1994-03-11 Retardtablette mit einem Gehalt an Diclofenac-Na
EP9500928 1995-03-13
PCT/EP1995/000928 WO1995024188A1 (de) 1994-03-11 1995-03-13 Retardtablette mit einem gehalt an diclofenac-na

Publications (3)

Publication Number Publication Date
FI963567A FI963567A (sv) 1996-09-10
FI963567A0 FI963567A0 (sv) 1996-09-10
FI118294B true FI118294B (sv) 2007-09-28

Family

ID=6512563

Family Applications (1)

Application Number Title Priority Date Filing Date
FI963567A FI118294B (sv) 1994-03-11 1996-09-10 Diklofenak-na innehållande depottablett

Country Status (14)

Country Link
US (1) US5874107A (sv)
EP (1) EP0749304B9 (sv)
JP (1) JPH09509953A (sv)
AT (1) ATE173399T1 (sv)
AU (1) AU692534B2 (sv)
CA (1) CA2185242C (sv)
DE (2) DE4408326A1 (sv)
DK (1) DK0749304T4 (sv)
ES (1) ES2126265T5 (sv)
FI (1) FI118294B (sv)
GR (1) GR3029278T3 (sv)
NO (1) NO317396B1 (sv)
PL (1) PL177607B1 (sv)
WO (1) WO1995024188A1 (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6262115B1 (en) * 1995-05-22 2001-07-17 Alza Coporation Method for the management of incontinence
US5912268A (en) * 1995-05-22 1999-06-15 Alza Corporation Dosage form and method for treating incontinence
AU3860797A (en) * 1997-07-16 1999-02-10 Antrin Research Limited Pharmaceutical formulations for oral administration
JP4565456B2 (ja) * 1999-11-02 2010-10-20 塩野義製薬株式会社 着色顆粒の色素定着法
DE10029201A1 (de) * 2000-06-19 2001-12-20 Basf Ag Verfahren zur Herstellung fester oraler Darreichungsformen mit retardierender Wirkstoffreisetzung
CA2479350A1 (en) * 2002-03-15 2003-09-25 Cypress Bioscience, Inc. Ne and 5-ht reuptake inhibitors for treating visceral pain syndromes
US20040132826A1 (en) * 2002-10-25 2004-07-08 Collegium Pharmaceutical, Inc. Modified release compositions of milnacipran
US20060003004A1 (en) * 2002-10-25 2006-01-05 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
US20040228830A1 (en) * 2003-01-28 2004-11-18 Collegium Pharmaceutical, Inc. Multiparticulate compositions of milnacipran for oral administration
US8107531B2 (en) * 2003-09-07 2012-01-31 Microsoft Corporation Signaling and repeat padding for skip frames

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786503A (en) † 1987-04-06 1988-11-22 Alza Corporation Dosage form comprising parallel lamine
US5236713A (en) * 1987-10-21 1993-08-17 Teikoku Seiyaku Kabushiki Kaisha Preparation for intermittently releasing active agent applicable to oral cavity
IT1264696B1 (it) * 1993-07-09 1996-10-04 Applied Pharma Res Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata

Also Published As

Publication number Publication date
PL316196A1 (en) 1996-12-23
NO317396B1 (no) 2004-10-25
AU692534B2 (en) 1998-06-11
ATE173399T1 (de) 1998-12-15
JPH09509953A (ja) 1997-10-07
US5874107A (en) 1999-02-23
DE4408326A1 (de) 1995-09-14
EP0749304B2 (de) 2004-03-03
AU2069595A (en) 1995-09-25
CA2185242C (en) 2004-11-23
EP0749304B9 (de) 2006-03-08
DK0749304T3 (da) 1999-08-02
DE59504270D1 (de) 1998-12-24
DK0749304T4 (da) 2004-03-29
WO1995024188A1 (de) 1995-09-14
FI963567A (sv) 1996-09-10
EP0749304A1 (de) 1996-12-27
ES2126265T3 (es) 1999-03-16
PL177607B1 (pl) 1999-12-31
FI963567A0 (sv) 1996-09-10
EP0749304B1 (de) 1998-11-18
NO963796L (no) 1996-11-06
ES2126265T5 (es) 2004-10-16
NO963796D0 (no) 1996-09-10
GR3029278T3 (en) 1999-05-28
CA2185242A1 (en) 1995-09-14

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