FI108135B - Menetelmä terapeuttisesti aktiivisten 7-okso-8-[2'-(1H-tetrasol-5-yyli)bifenyl-4-yylimetyyli]-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidiinijohdannaisten valmistamiseksi - Google Patents

Menetelmä terapeuttisesti aktiivisten 7-okso-8-[2'-(1H-tetrasol-5-yyli)bifenyl-4-yylimetyyli]-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidiinijohdannaisten valmistamiseksi Download PDF

Info

Publication number
FI108135B
FI108135B FI941309A FI941309A FI108135B FI 108135 B FI108135 B FI 108135B FI 941309 A FI941309 A FI 941309A FI 941309 A FI941309 A FI 941309A FI 108135 B FI108135 B FI 108135B
Authority
FI
Finland
Prior art keywords
hydroxy
compound
biphenyl
formula
ylmethyl
Prior art date
Application number
FI941309A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI941309A (fi
FI941309A0 (fi
Inventor
John Watson Ellingboe
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/179,461 external-priority patent/US5466692A/en
Application filed by American Home Prod filed Critical American Home Prod
Publication of FI941309A0 publication Critical patent/FI941309A0/fi
Publication of FI941309A publication Critical patent/FI941309A/fi
Application granted granted Critical
Publication of FI108135B publication Critical patent/FI108135B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI941309A 1993-03-24 1994-03-21 Menetelmä terapeuttisesti aktiivisten 7-okso-8-[2'-(1H-tetrasol-5-yyli)bifenyl-4-yylimetyyli]-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidiinijohdannaisten valmistamiseksi FI108135B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US3661593A 1993-03-24 1993-03-24
US3661593 1993-03-24
US17946194 1994-01-10
US08/179,461 US5466692A (en) 1993-03-24 1994-01-10 Substituted pyridopyrimidines and antihypertensives

Publications (3)

Publication Number Publication Date
FI941309A0 FI941309A0 (fi) 1994-03-21
FI941309A FI941309A (fi) 1994-09-25
FI108135B true FI108135B (fi) 2001-11-30

Family

ID=26713326

Family Applications (1)

Application Number Title Priority Date Filing Date
FI941309A FI108135B (fi) 1993-03-24 1994-03-21 Menetelmä terapeuttisesti aktiivisten 7-okso-8-[2'-(1H-tetrasol-5-yyli)bifenyl-4-yylimetyyli]-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidiinijohdannaisten valmistamiseksi

Country Status (17)

Country Link
EP (2) EP0618207B1 (ja)
JP (1) JPH06321945A (ja)
AT (1) ATE175413T1 (ja)
AU (1) AU669966B2 (ja)
BR (1) BR9401261A (ja)
CA (1) CA2119692A1 (ja)
DE (1) DE69415706T2 (ja)
DK (1) DK0618207T3 (ja)
ES (1) ES2126061T3 (ja)
FI (1) FI108135B (ja)
GR (1) GR3029879T3 (ja)
HK (1) HK1011358A1 (ja)
HU (1) HU222240B1 (ja)
LV (1) LV12261B (ja)
NZ (1) NZ260164A (ja)
PH (1) PH30373A (ja)
SG (1) SG47714A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2001103044A (ru) 1998-07-06 2003-08-10 Бристол-Маерс Сквибб Ко. (Us) Бенилсульфонамиды в качестве двойных антагонистов ангиотензиновых эндотелиновых рецепторов
WO2008148812A1 (en) * 2007-06-07 2008-12-11 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. 5beta, 14beta-androstane derivatives useful for the treatment of restenosis after angioplastic or endoartherectomy and diseases due to organ fibrosis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US521797A (en) * 1894-06-26 Half to john m
BG94957A (bg) * 1990-08-10 1993-12-24 Ciba - Geigy Ag Пиримидинови производни и средство за борба срещу вредители по растенията
US5290780A (en) * 1991-01-30 1994-03-01 American Cyanamid Co. Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
IL100917A0 (en) * 1991-02-16 1992-11-15 Fisons Plc Pyridinone and pyrimidinone derivatives,their preparation and pharmaceutical compositions containing them
AU1625192A (en) * 1991-05-31 1992-12-03 Zeneca Limited Heterocyclic derivatives
US5149699A (en) * 1991-10-24 1992-09-22 American Home Products Corporation Substituted pyridopyrimidines useful as antgiotensin II antagonists
TW226375B (ja) * 1991-10-24 1994-07-11 American Home Prod
GB9125842D0 (en) * 1991-12-04 1992-02-05 Ici Plc Heterocyclic derivatives

Also Published As

Publication number Publication date
FI941309A (fi) 1994-09-25
AU5799794A (en) 1994-09-29
HU222240B1 (hu) 2003-05-28
EP0618207B1 (en) 1999-01-07
LV12261B (en) 1999-09-20
ATE175413T1 (de) 1999-01-15
DK0618207T3 (da) 1999-08-30
JPH06321945A (ja) 1994-11-22
HU9400822D0 (en) 1994-06-28
HK1011358A1 (en) 1999-07-09
PH30373A (en) 1997-04-02
BR9401261A (pt) 1994-11-22
HUT66964A (en) 1995-01-30
CA2119692A1 (en) 1994-09-25
LV12261A (lv) 1999-04-20
DE69415706T2 (de) 1999-05-20
AU669966B2 (en) 1996-06-27
FI941309A0 (fi) 1994-03-21
EP0863143A1 (en) 1998-09-09
ES2126061T3 (es) 1999-03-16
SG47714A1 (en) 1998-04-17
DE69415706D1 (de) 1999-02-18
EP0618207A1 (en) 1994-10-05
GR3029879T3 (en) 1999-07-30
NZ260164A (en) 1996-02-27

Similar Documents

Publication Publication Date Title
US5128327A (en) Angiotensin II antagonists incorporating a nitrogen containing six membered ring heterocycle
EP0516392B1 (en) Naphthyridine derivatives as angiotensin II inhibitors
US5387592A (en) Substituted benzoxazole, benzthiazole, and benzimidazole derivatives as angiotensin II antagonists
US5466692A (en) Substituted pyridopyrimidines and antihypertensives
US5532276A (en) Imidazopyridines
EP2757882B1 (en) Imidazopyridyl compounds as aldosterone synthase inhibitors
IE83625B1 (en) Imidazopyridine
JPH05222039A (ja) 置換ピリミジン類
AU2002233706C1 (en) Pyridopyrimidine or naphthyridine derivative
US5281613A (en) Heterocyclic compounds
JPH05286939A (ja) ビフェニル置換キノリン誘導体
EP0511791A2 (en) Pyrrolopyridine derivatives as Angiotensin inhibitors
US5198434A (en) Angiotensin ii antagonizing fused pyridinyloxy containing derivatives
CA2191947C (en) Pirydyl imidazole derivatives and processes for the preparation thereof
EP0743943B1 (en) Pyridyl imidazole derivatives and processes for the preparation thereof
FI108135B (fi) Menetelmä terapeuttisesti aktiivisten 7-okso-8-[2'-(1H-tetrasol-5-yyli)bifenyl-4-yylimetyyli]-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidiinijohdannaisten valmistamiseksi
CS220343B2 (en) Method of producing new imidazoquinazoline derivatives
JPH0680664A (ja) 新規キノリン誘導体
CZ322192A3 (en) Substituted pyrimidine derivatives, process of their preparation and pharmaceutical preparations in which they are comprised
JPH06312927A (ja) アンジオテンシンii拮抗薬
WO1993024501A1 (en) Phosphorus containing heterocyclic compounds as angiotensins antagonists
WO1993024487A1 (en) Nitrogen containing heterocyclic compounds as angiotensin-ii-antagonists
KR980009264A (ko) 벤조푸란계 치환기를 갖는 피리딜 이미다졸 유도체, 그의 제조방법 및 그를 함유하는 혈압강하제
CS270592B2 (en) Method of 1,4-dihydropyridines production