DE69415706D1 - Substituierte Pyridopyrimidine als Antihypertensiva - Google Patents

Substituierte Pyridopyrimidine als Antihypertensiva

Info

Publication number
DE69415706D1
DE69415706D1 DE69415706T DE69415706T DE69415706D1 DE 69415706 D1 DE69415706 D1 DE 69415706D1 DE 69415706 T DE69415706 T DE 69415706T DE 69415706 T DE69415706 T DE 69415706T DE 69415706 D1 DE69415706 D1 DE 69415706D1
Authority
DE
Germany
Prior art keywords
c6alkyl
hydroxy
carboxy
chem
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69415706T
Other languages
English (en)
Other versions
DE69415706T2 (de
Inventor
John Watson Ellingboe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/179,461 external-priority patent/US5466692A/en
Application filed by American Home Products Corp filed Critical American Home Products Corp
Application granted granted Critical
Publication of DE69415706D1 publication Critical patent/DE69415706D1/de
Publication of DE69415706T2 publication Critical patent/DE69415706T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69415706T 1993-03-24 1994-03-16 Substituierte Pyridopyrimidine als Antihypertensiva Expired - Fee Related DE69415706T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3661593A 1993-03-24 1993-03-24
US08/179,461 US5466692A (en) 1993-03-24 1994-01-10 Substituted pyridopyrimidines and antihypertensives

Publications (2)

Publication Number Publication Date
DE69415706D1 true DE69415706D1 (de) 1999-02-18
DE69415706T2 DE69415706T2 (de) 1999-05-20

Family

ID=26713326

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69415706T Expired - Fee Related DE69415706T2 (de) 1993-03-24 1994-03-16 Substituierte Pyridopyrimidine als Antihypertensiva

Country Status (17)

Country Link
EP (2) EP0618207B1 (de)
JP (1) JPH06321945A (de)
AT (1) ATE175413T1 (de)
AU (1) AU669966B2 (de)
BR (1) BR9401261A (de)
CA (1) CA2119692A1 (de)
DE (1) DE69415706T2 (de)
DK (1) DK0618207T3 (de)
ES (1) ES2126061T3 (de)
FI (1) FI108135B (de)
GR (1) GR3029879T3 (de)
HK (1) HK1011358A1 (de)
HU (1) HU222240B1 (de)
LV (1) LV12261B (de)
NZ (1) NZ260164A (de)
PH (1) PH30373A (de)
SG (1) SG47714A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2001103044A (ru) 1998-07-06 2003-08-10 Бристол-Маерс Сквибб Ко. (Us) Бенилсульфонамиды в качестве двойных антагонистов ангиотензиновых эндотелиновых рецепторов
WO2008148812A1 (en) * 2007-06-07 2008-12-11 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. 5beta, 14beta-androstane derivatives useful for the treatment of restenosis after angioplastic or endoartherectomy and diseases due to organ fibrosis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US521797A (en) * 1894-06-26 Half to john m
BG94957A (bg) * 1990-08-10 1993-12-24 Ciba - Geigy Ag Пиримидинови производни и средство за борба срещу вредители по растенията
US5290780A (en) * 1991-01-30 1994-03-01 American Cyanamid Co. Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
IL100917A0 (en) * 1991-02-16 1992-11-15 Fisons Plc Pyridinone and pyrimidinone derivatives,their preparation and pharmaceutical compositions containing them
AU1625192A (en) * 1991-05-31 1992-12-03 Zeneca Limited Heterocyclic derivatives
US5149699A (en) * 1991-10-24 1992-09-22 American Home Products Corporation Substituted pyridopyrimidines useful as antgiotensin II antagonists
TW226375B (de) * 1991-10-24 1994-07-11 American Home Prod
GB9125842D0 (en) * 1991-12-04 1992-02-05 Ici Plc Heterocyclic derivatives

Also Published As

Publication number Publication date
FI941309A (fi) 1994-09-25
AU5799794A (en) 1994-09-29
HU222240B1 (hu) 2003-05-28
EP0618207B1 (de) 1999-01-07
LV12261B (en) 1999-09-20
ATE175413T1 (de) 1999-01-15
DK0618207T3 (da) 1999-08-30
JPH06321945A (ja) 1994-11-22
HU9400822D0 (en) 1994-06-28
HK1011358A1 (en) 1999-07-09
PH30373A (en) 1997-04-02
FI108135B (fi) 2001-11-30
BR9401261A (pt) 1994-11-22
HUT66964A (en) 1995-01-30
CA2119692A1 (en) 1994-09-25
LV12261A (lv) 1999-04-20
DE69415706T2 (de) 1999-05-20
AU669966B2 (en) 1996-06-27
FI941309A0 (fi) 1994-03-21
EP0863143A1 (de) 1998-09-09
ES2126061T3 (es) 1999-03-16
SG47714A1 (en) 1998-04-17
EP0618207A1 (de) 1994-10-05
GR3029879T3 (en) 1999-07-30
NZ260164A (en) 1996-02-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: WYETH (N.D.GES.D. STAATES DELAWARE), MADISON, N.J.

8339 Ceased/non-payment of the annual fee