FI103764B1 - Kudosta kosteuttava koostumus ja menetelmä sen valmistamiseksi - Google Patents

Kudosta kosteuttava koostumus ja menetelmä sen valmistamiseksi

Info

Publication number
FI103764B1
FI103764B1 FI921932A FI921932A FI103764B1 FI 103764 B1 FI103764 B1 FI 103764B1 FI 921932 A FI921932 A FI 921932A FI 921932 A FI921932 A FI 921932A FI 103764 B1 FI103764 B1 FI 103764B1
Authority
FI
Finland
Prior art keywords
making
moisturizing composition
tissue moisturizing
tissue
composition
Prior art date
Application number
FI921932A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI103764B (fi
FI921932A0 (fi
FI921932A (fi
Inventor
Joseph R Robinson
Original Assignee
Columbia Lab Bermuda Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia Lab Bermuda Ltd filed Critical Columbia Lab Bermuda Ltd
Publication of FI921932A0 publication Critical patent/FI921932A0/fi
Publication of FI921932A publication Critical patent/FI921932A/fi
Application granted granted Critical
Publication of FI103764B publication Critical patent/FI103764B/fi
Publication of FI103764B1 publication Critical patent/FI103764B1/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • A61K31/78Polymers containing oxygen of acrylic acid or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8105Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • A61K8/8117Homopolymers or copolymers of aromatic olefines, e.g. polystyrene; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/817Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8194Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/91Graft copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Reproductive Health (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI921932A 1989-10-31 1992-04-29 Kudosta kosteuttava koostumus ja menetelmä sen valmistamiseksi FI103764B1 (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US42977089A 1989-10-31 1989-10-31
US42975589A 1989-10-31 1989-10-31
US42977089 1989-10-31
US42975589 1989-10-31
US9006087 1990-10-24
PCT/US1990/006087 WO1991006283A1 (en) 1989-10-31 1990-10-24 Tissue moisturizing composition and method

Publications (4)

Publication Number Publication Date
FI921932A0 FI921932A0 (fi) 1992-04-29
FI921932A FI921932A (fi) 1992-04-29
FI103764B FI103764B (fi) 1999-09-30
FI103764B1 true FI103764B1 (fi) 1999-09-30

Family

ID=27028332

Family Applications (1)

Application Number Title Priority Date Filing Date
FI921932A FI103764B1 (fi) 1989-10-31 1992-04-29 Kudosta kosteuttava koostumus ja menetelmä sen valmistamiseksi

Country Status (26)

Country Link
US (1) US5968500A (el)
EP (1) EP0500807B1 (el)
JP (1) JP2510052B2 (el)
KR (1) KR100218654B1 (el)
AR (1) AR243728A1 (el)
AT (1) ATE181824T1 (el)
AU (1) AU639069B2 (el)
BR (1) BR9007807A (el)
CA (1) CA2072148C (el)
DE (1) DE69033199T2 (el)
DK (1) DK0500807T3 (el)
ES (1) ES2134769T3 (el)
FI (1) FI103764B1 (el)
GR (1) GR3031288T3 (el)
HU (3) HU227563B1 (el)
IE (1) IE62386B1 (el)
IL (1) IL96148A (el)
MA (1) MA22756A1 (el)
MC (1) MC2204A1 (el)
MY (1) MY105322A (el)
NO (1) NO301362B1 (el)
NZ (2) NZ272331A (el)
PE (1) PE27891A1 (el)
PT (1) PT95729B (el)
RU (1) RU2104034C1 (el)
WO (1) WO1991006283A1 (el)

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JP3064417B2 (ja) * 1990-08-21 2000-07-12 セラテック,インコーポレイテッド 放出制御性製剤及び方法
US5686094A (en) * 1991-04-01 1997-11-11 Theratech, Inc. Controlled release formulations for the treatment of xerostomia
DE4113684B4 (de) * 1991-04-26 2005-02-03 Sommermeyer, Klaus, Dr. Spraybares Mund- und Rachenpflegemittel gegen Trockenheit der Schleimhaut
IT1250748B (it) * 1991-08-02 1995-04-21 Poli Ind Chimica Spa Formulazioni utili per il trattamento della secchezza vaginale
IL101056A (en) * 1992-02-24 1997-03-18 Res & Dev Co Ltd Composition for nasal treatment
GR1002418B (el) * 1992-07-29 1996-08-21 Johnson & Johnson Consumer Products Inc. Βιοεπισυναπτομενες συνθεσεις θεραπειας και μεθοδοι χρησης.
GR1001412B (el) * 1992-10-12 1993-11-30 Poli Ind Chimica Spa Συν?έσεις χρήσιμες δια την ?εραπευτική αγωγή της ξηρότητος του κόλπου.
ES2049665B1 (es) * 1992-10-13 1994-11-01 Poli Ind Chimica Spa Formulaciones utiles para el tratamiento de la sequedad viginal.
US5667492A (en) * 1994-10-07 1997-09-16 Columbia Laboratories, Inc. Use and composition of an anti-sexually transmitted diseases formulation
US6596777B1 (en) 1997-05-29 2003-07-22 Mcneil-Ppc, Inc. Moisture containing compositions that are spreadable onto and adherable to biomembranes
US20040096422A1 (en) * 1997-06-17 2004-05-20 Schwartz Herbert E. Compositions of polyacids and polyethers and methods for their use in reducing pain
US20050074495A1 (en) * 1997-06-17 2005-04-07 Fziomed, Inc. Compositions of polyacids and methods for their use in reducing adhesions
US6869938B1 (en) 1997-06-17 2005-03-22 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use in reducing adhesions
US7192984B2 (en) * 1997-06-17 2007-03-20 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use as dermal fillers
ES2311455T3 (es) * 1999-04-02 2009-02-16 Fziomed, Inc. Composiciones de poliacidos, de polimeros no ionicos de monomeros de oxido de alquileno y cationes multivalentes y su utilizacion para la reduccion de adherencias.
US6479045B2 (en) 1999-12-22 2002-11-12 Columbia Laboratories, Inc. Vaginal pH buffering for preventing miscarriage and premature labor, by treating or preventing bacterial vaginosis
US6566345B2 (en) 2000-04-28 2003-05-20 Fziomed, Inc. Polyacid/polyalkylene oxide foams and gels and methods for their delivery
US6284235B1 (en) 2000-02-11 2001-09-04 National Starch And Chemical Company Investment Holding Corporation Bioadhesive composition
US20020010150A1 (en) * 2000-04-28 2002-01-24 Cortese Stephanie M. Homostatic compositions of polyacids and polyalkylene oxides and methods for their use
US6592860B1 (en) * 2000-05-30 2003-07-15 Soluble Systems, Llc Composition and applicator for topical substance delivery
DE10051858A1 (de) * 2000-10-19 2002-06-06 Guenther Beisel Verwendung von biologisch abbaubaren, substituierten Kohlenwasserstoffen deren Ester, Ether und/oder Amide als Nasensalbe oder Nasentropfen zur Prophylaxe von inhalationsallergischen Reaktionen und zur Pflege der Nasenschleimhaut
DE10064950A1 (de) * 2000-12-23 2002-07-11 Impetus Ag Basel Thixotropes Nasenspray
WO2002064113A1 (en) * 2001-02-15 2002-08-22 Access Pharmaceuticals, Inc. Liquid formulations for the prevention and treatment of mucosal diseases and disorders
US7544348B2 (en) * 2001-02-15 2009-06-09 Access Pharmaceuticals, Inc. Liquid formulations for the prevention and treatment of mucosal diseases and disorders
US6585997B2 (en) 2001-08-16 2003-07-01 Access Pharmaceuticals, Inc. Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds
US20060073174A1 (en) * 2001-08-16 2006-04-06 Access Pharmaceuticals, Inc. Adherent and erodible film to treat a moist surface of a body tissue
EP1450739A4 (en) * 2001-10-12 2008-12-17 Cns Inc NASAL MOISTURIZING GEL AND APPLICATOR
US8425892B2 (en) 2001-10-29 2013-04-23 Columbia Laboratories, Inc. Extended, controlled-release pharmaceutical compositions using charged polymers
US7846478B2 (en) * 2002-01-31 2010-12-07 Henkel Ag & Co. Kgaa Bioadhesive composition
US20060057227A1 (en) * 2002-02-15 2006-03-16 Fisher Jeffrey J Throat spray
US20030204180A1 (en) * 2002-04-30 2003-10-30 Kimberly-Clark Worldwide, Inc. Temperature responsive delivery systems
US8524200B2 (en) 2002-09-11 2013-09-03 The Procter & Gamble Company Tooth whitening products
KR101060930B1 (ko) * 2002-10-31 2011-08-30 이데미쓰 테크노파인 가부시키가이샤 감촉 및 유분산성이 우수한 화장료
ES2237298B1 (es) 2003-07-16 2006-11-01 Italfarmaco, S.A. Formulaciones mucoadhesivas semisolidas.
US8455016B2 (en) * 2004-03-12 2013-06-04 Melbj Holdings, Llc Treatment for meibomian gland dysfunction or obstruction
US20050202097A1 (en) * 2004-03-12 2005-09-15 Melbj Holdings, Llc, Florida Lubricant for the ocular surface
US8703198B2 (en) 2005-03-02 2014-04-22 Aquatrove Biosciences Water-based personal moisturizers and lubricants, in particular vaginal lubricants, and uses thereof
US7252834B2 (en) * 2005-04-25 2007-08-07 Clemson University Research Foundation (Curf) Elastin stabilization of connective tissue
AU2013277007B2 (en) * 2006-03-01 2016-04-14 Mancini Holdings Pty Ltd Aqueous moisturizers and lubircants and uses thereof
WO2009064806A1 (en) * 2007-11-12 2009-05-22 Endologix, Inc. Method and agent for in-situ stabilization of vascular tissue
US20090214654A1 (en) * 2008-02-21 2009-08-27 Isenburg Jason C Treatment of aneurysm with application of connective tissue stabilization agent in combination with a delivery vehicle
US20100016833A1 (en) * 2008-07-15 2010-01-21 Ogle Matthew F Devices for the Treatment of Vascular Aneurysm
US20100119605A1 (en) * 2008-11-12 2010-05-13 Isenburg Jason C Compositions for tissue stabilization
GB0905677D0 (en) * 2009-04-01 2009-05-20 Yes Syzygy Ltd Intimate lubrication kit
WO2011044455A1 (en) * 2009-10-09 2011-04-14 Vatrix Medical, Inc. In vivo chemical stabilization of vulnerable plaque
US8444624B2 (en) * 2009-10-19 2013-05-21 Vatrix Medical, Inc. Vascular medical devices with sealing elements and procedures for the treatment of isolated vessel sections
EP2544543A1 (en) * 2010-03-12 2013-01-16 Scott Cordray Method of treatment
US8911468B2 (en) 2011-01-31 2014-12-16 Vatrix Medical, Inc. Devices, therapeutic compositions and corresponding percutaneous treatment methods for aortic dissection
JP2014516695A (ja) 2011-05-18 2014-07-17 バトリックス・メディカル・インコーポレイテッド 血管安定化用被覆バルーン
US9283241B2 (en) 2012-07-10 2016-03-15 Clemson University Treatment to render implants resistant to diabetes
WO2016127020A1 (en) * 2015-02-06 2016-08-11 Noven Pharmaceuticals, Inc. Pressure-sensitive adhesives for transdermal drug delivery
WO2018038472A1 (ko) * 2016-08-25 2018-03-01 문득곤 화장료 조성물 및 피부에 유용성분을 공급하는 방법

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SE7500077L (sv) * 1974-04-20 1975-10-21 Henkel & Cie Gmbh Anvendning av karboxyl- resp. karboxylat- och aldehydgrupper innehallande polymerer som hudfuktighetsbevarande medel i hudvards- och hudskyddsmedel.
US4863725A (en) * 1982-10-27 1989-09-05 Deckner George E Novel clear oil-free moisturizer composition
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JPS6172706A (ja) * 1984-09-18 1986-04-14 Showa Denko Kk 化粧料
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IE63392B1 (en) * 1988-02-08 1995-04-19 Insite Vision Inc Ophthalmic suspensions

Also Published As

Publication number Publication date
FI103764B (fi) 1999-09-30
GR3031288T3 (en) 1999-12-31
HU227563B1 (en) 2011-08-29
EP0500807B1 (en) 1999-07-07
US5968500A (en) 1999-10-19
NO301362B1 (no) 1997-10-20
DE69033199T2 (de) 1999-10-28
EP0500807A1 (en) 1992-09-02
FI921932A0 (fi) 1992-04-29
NZ272331A (en) 1996-11-26
IL96148A (en) 1995-08-31
MA22756A1 (fr) 1993-10-01
FI921932A (fi) 1992-04-29
IL96148A0 (en) 1991-07-18
WO1991006283A1 (en) 1991-05-16
KR100218654B1 (ko) 1999-09-01
MY105322A (en) 1994-09-30
NO921686L (no) 1992-06-29
IE62386B1 (en) 1995-01-25
DE69033199D1 (de) 1999-08-12
MC2204A1 (fr) 1992-11-26
ATE181824T1 (de) 1999-07-15
JP2510052B2 (ja) 1996-06-26
PE27891A1 (es) 1991-10-29
PT95729A (pt) 1991-09-13
DK0500807T3 (da) 2000-02-07
AU639069B2 (en) 1993-07-15
ES2134769T3 (es) 1999-10-16
AR243728A1 (es) 1993-09-30
AU7033191A (en) 1991-05-31
PT95729B (pt) 1998-05-29
JPH05504338A (ja) 1993-07-08
RU2104034C1 (ru) 1998-02-10
KR920703010A (ko) 1992-12-17
HUT68635A (en) 1995-07-28
NO921686D0 (no) 1992-04-29
CA2072148A1 (en) 1991-05-01
NZ235903A (en) 1996-11-26
HU9201465D0 (en) 1992-07-28
CA2072148C (en) 2002-04-23
BR9007807A (pt) 1992-09-29
IE903891A1 (en) 1991-05-08

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