FI102536B1 - Menetelmä terapeuttisesti käyttökelpoisten yhdisteiden valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten yhdisteiden valmistamiseksi

Info

Publication number
FI102536B1
FI102536B1 FI913639A FI913639A FI102536B1 FI 102536 B1 FI102536 B1 FI 102536B1 FI 913639 A FI913639 A FI 913639A FI 913639 A FI913639 A FI 913639A FI 102536 B1 FI102536 B1 FI 102536B1
Authority
FI
Finland
Prior art keywords
alkyl
hydrogen
optionally protected
halo
chem
Prior art date
Application number
FI913639A
Other languages
English (en)
Swedish (sv)
Other versions
FI102536B (fi
FI913639A0 (fi
FI913639A (fi
Inventor
Jeremy Gilmore
Alec Todd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909016790A external-priority patent/GB9016790D0/en
Priority claimed from GB919107486A external-priority patent/GB9107486D0/en
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of FI913639A0 publication Critical patent/FI913639A0/fi
Publication of FI913639A publication Critical patent/FI913639A/fi
Application granted granted Critical
Publication of FI102536B publication Critical patent/FI102536B/fi
Publication of FI102536B1 publication Critical patent/FI102536B1/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing alicyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
FI913639A 1990-07-31 1991-07-30 Menetelmä terapeuttisesti käyttökelpoisten yhdisteiden valmistamiseksi FI102536B1 (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB909016790A GB9016790D0 (en) 1990-07-31 1990-07-31 Pharmaceutical compounds
GB9016790 1990-07-31
GB9107486 1991-04-09
GB919107486A GB9107486D0 (en) 1991-04-09 1991-04-09 Pharmaceutical compounds

Publications (4)

Publication Number Publication Date
FI913639A0 FI913639A0 (fi) 1991-07-30
FI913639A FI913639A (fi) 1992-02-01
FI102536B FI102536B (fi) 1998-12-31
FI102536B1 true FI102536B1 (fi) 1998-12-31

Family

ID=26297410

Family Applications (1)

Application Number Title Priority Date Filing Date
FI913639A FI102536B1 (fi) 1990-07-31 1991-07-30 Menetelmä terapeuttisesti käyttökelpoisten yhdisteiden valmistamiseksi

Country Status (24)

Country Link
EP (1) EP0469833B1 (fi)
JP (1) JP3220191B2 (fi)
KR (1) KR0179985B1 (fi)
CN (1) CN1040108C (fi)
AT (1) ATE184280T1 (fi)
AU (1) AU654140B2 (fi)
CA (1) CA2048096C (fi)
CZ (1) CZ279932B6 (fi)
DE (1) DE69131592T2 (fi)
DK (1) DK0469833T3 (fi)
ES (1) ES2137158T3 (fi)
FI (1) FI102536B1 (fi)
GR (1) GR3032038T3 (fi)
HU (2) HU213604B (fi)
IE (1) IE912670A1 (fi)
IL (1) IL98990A (fi)
MX (1) MX9100414A (fi)
MY (1) MY131141A (fi)
NO (1) NO300133B1 (fi)
NZ (1) NZ239168A (fi)
PH (1) PH30487A (fi)
PT (1) PT98475B (fi)
SK (1) SK279197B6 (fi)
YU (1) YU47839B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9122590D0 (en) * 1991-10-24 1991-12-04 Lilly Industries Ltd Pharmaceutical compounds
US5273986A (en) * 1992-07-02 1993-12-28 Hoffmann-La Roche Inc. Cycloalkylthiazoles
US5416211A (en) * 1992-09-25 1995-05-16 Eli Lilly And Company Process for preparing 5-substituted pyrrolo-[2,3-d]pyrimidines
US5486612A (en) * 1993-12-14 1996-01-23 Eli Lilly And Company N-benzyl dihydroindole LTD4 antagonists
WO1996036347A1 (en) * 1995-05-17 1996-11-21 Eli Lilly And Company Use of leukotriene antagonists for alzheimer's disease
US6160120A (en) * 1996-11-19 2000-12-12 Eli Lilly And Company Process for preparing n-benzyl indoles
GB9523948D0 (en) * 1995-11-23 1996-01-24 Univ East Anglia Process for preparing n-benzyl indoles
CA2583828A1 (en) * 2004-10-12 2006-04-27 Decode Genetics, Inc. Carboxylic acid peri-substituted bicyclics for occlusive artery disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8524157D0 (en) * 1984-10-19 1985-11-06 Ici America Inc Heterocyclic amides
MY103259A (en) * 1987-04-15 1993-05-29 Ici America Inc Aliphatic carboxamides
GB8728051D0 (en) * 1987-12-01 1988-01-06 Leo Pharm Prod Ltd Chemical compounds
US4970207A (en) * 1988-07-07 1990-11-13 Fujisawa Pharmaceutical Company, Ltd. Benzodiazepine derivatives

Also Published As

Publication number Publication date
EP0469833B1 (en) 1999-09-08
DK0469833T3 (da) 1999-12-20
AU8139991A (en) 1992-02-06
PT98475A (pt) 1992-06-30
YU47839B (sr) 1996-01-09
MY131141A (en) 2007-07-31
SK279197B6 (sk) 1998-07-08
ES2137158T3 (es) 1999-12-16
HUT60491A (en) 1992-09-28
JP3220191B2 (ja) 2001-10-22
IL98990A0 (en) 1992-07-15
NO912963L (no) 1992-02-03
DE69131592T2 (de) 2000-01-20
CN1040108C (zh) 1998-10-07
NO912963D0 (no) 1991-07-30
PH30487A (en) 1997-05-28
CA2048096A1 (en) 1992-02-01
HU211952A9 (en) 1996-01-29
NO300133B1 (no) 1997-04-14
CN1061413A (zh) 1992-05-27
FI102536B (fi) 1998-12-31
EP0469833A1 (en) 1992-02-05
DE69131592D1 (de) 1999-10-14
MX9100414A (es) 1992-02-28
ATE184280T1 (de) 1999-09-15
KR0179985B1 (ko) 1999-03-20
YU132591A (sh) 1994-01-20
IE912670A1 (en) 1992-02-12
HU912535D0 (en) 1992-01-28
CA2048096C (en) 2002-09-17
CS238091A3 (en) 1992-03-18
IL98990A (en) 1995-06-29
FI913639A0 (fi) 1991-07-30
FI913639A (fi) 1992-02-01
NZ239168A (en) 1993-05-26
CZ279932B6 (cs) 1995-08-16
AU654140B2 (en) 1994-10-27
PT98475B (pt) 1997-11-28
KR920002582A (ko) 1992-02-28
GR3032038T3 (en) 2000-03-31
JPH06220045A (ja) 1994-08-09
HU213604B (en) 1997-08-28

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