ES8800153A1 - Procedimiento para la obtencion de formulaciones medicionales solidas de nitrendipina cristalina. - Google Patents

Procedimiento para la obtencion de formulaciones medicionales solidas de nitrendipina cristalina.

Info

Publication number
ES8800153A1
ES8800153A1 ES546799A ES546799A ES8800153A1 ES 8800153 A1 ES8800153 A1 ES 8800153A1 ES 546799 A ES546799 A ES 546799A ES 546799 A ES546799 A ES 546799A ES 8800153 A1 ES8800153 A1 ES 8800153A1
Authority
ES
Spain
Prior art keywords
weight
preparation
parts
solid pharmaceutical
nitrendipine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES546799A
Other languages
English (en)
Other versions
ES546799A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6245068&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8800153(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES546799A0 publication Critical patent/ES546799A0/es
Publication of ES8800153A1 publication Critical patent/ES8800153A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

PROCEDIMIENTO PARA OBTENER FORMULACIONES MEDICINALES SOLIDAS DE NITRENDIPINA CRISTALINA. COMPRENDE: A) HACER REACCIONAR AL ESTER DEL ACIDO ILIDEN-BETA-CETOCARBOXILICO DE FORMULA (II), EN ETANOL, ENTRE 20 Y 120GC, PARA OBTENER NITRENDIPINA SOLIDA; B) GRANULAR A LA NITRENDIPINA SOLIDA, MEDIANTE SUSTANCIAS AUXILIARES Y PORTADORAS; Y C) TRANSFORMAR LA MASA EN TABLETAS, PILDORAS O GRAGESA PARA SU POSTERIOR APLICACION. SE UTILIZA COMO REDUCTOR DE LA PESION SANGUINEA. *FORMULA*
ES546799A 1984-09-11 1985-09-09 Procedimiento para la obtencion de formulaciones medicionales solidas de nitrendipina cristalina. Expired ES8800153A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843433239 DE3433239A1 (de) 1984-09-11 1984-09-11 Feste arzneizubereitung enthaltend nitrendipin und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
ES546799A0 ES546799A0 (es) 1987-10-16
ES8800153A1 true ES8800153A1 (es) 1987-10-16

Family

ID=6245068

Family Applications (1)

Application Number Title Priority Date Filing Date
ES546799A Expired ES8800153A1 (es) 1984-09-11 1985-09-09 Procedimiento para la obtencion de formulaciones medicionales solidas de nitrendipina cristalina.

Country Status (13)

Country Link
US (1) US4724141A (es)
EP (1) EP0176773B1 (es)
JP (1) JPH0761960B2 (es)
KR (1) KR920006909B1 (es)
AT (1) ATE48943T1 (es)
AU (1) AU578114B2 (es)
CA (1) CA1261271A (es)
DE (2) DE3433239A1 (es)
DK (1) DK411485A (es)
ES (1) ES8800153A1 (es)
GR (1) GR852176B (es)
IL (1) IL76332A0 (es)
ZA (1) ZA856916B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1178511B (it) * 1984-09-14 1987-09-09 Pharmatec Spa Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio
US4771057A (en) * 1986-02-03 1988-09-13 University Of Alberta Reduced pyridyl derivatives with cardiovascular regulating properties
DE3639073A1 (de) * 1986-11-14 1988-05-26 Klinge Co Chem Pharm Fab Feste arzneizubereitungen und verfahren zu ihrer herstellung
US5571827A (en) * 1990-03-13 1996-11-05 Sepracor Inc. Methods and compositions for treating hypertension, angina and other disorders using optically pure s(-) nitrendipine
US5190962A (en) * 1990-03-13 1993-03-02 Sepracor, Inc. Treating hypertension
FR2661611B1 (fr) * 1990-05-04 1994-11-18 Theramex Nouvelles compositions pharmaceutiques a base de polycarbophil et leur procede d'obtention.
SI9300504A (en) * 1993-09-28 1995-04-30 Krka Process for preparation solid dispersions and deposits of calcium antagonist dihidropyrimidine derivates and pharmaceutical compositions comprising the same
JP2713549B2 (ja) * 1994-05-17 1998-02-16 財団法人工業技術研究院 防湿性漢方製剤
JP2656727B2 (ja) * 1994-05-17 1997-09-24 財団法人工業技術研究院 防湿性漢方顆粒製剤
ES2257886T3 (es) * 1998-12-01 2006-08-01 Dr. Reddy's Research Foundation Nueva composicion farmaceutica y el proceso para su preparacion.
EG23951A (en) * 1999-03-25 2008-01-29 Otsuka Pharma Co Ltd Cilostazol preparation
JP4748839B2 (ja) * 1999-03-25 2011-08-17 大塚製薬株式会社 シロスタゾール製剤
CA2430288C (en) 2000-12-01 2009-03-10 Kyowa Hakko Kogyo Co., Ltd. A composition improved in the solubility or oral absorbability
FR2827517B1 (fr) 2001-07-23 2003-10-24 Bioalliance Pharma Systemes therapeutiques bioadhesifs a liberation prolongee
DE10355461A1 (de) * 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
EP1837020A1 (en) 2006-03-24 2007-09-26 Bioalliance Pharma Mucosal bioadhesive slow release carrier for delivering active principles
EP3002005A1 (en) * 2014-09-30 2016-04-06 Molkerei Meggle Wasserburg GmbH & Co. Kg Direct compression excipient based on lactose, cellulose and starch
US11883404B2 (en) 2016-03-04 2024-01-30 Taiho Pharmaceuticals Co., Ltd. Preparation and composition for treatment of malignant tumors
AU2017226389B2 (en) 2016-03-04 2023-02-02 Taiho Pharmaceutical Co., Ltd. Preparation and composition for treatment of malignant tumors
PL3769765T3 (pl) * 2018-03-19 2024-06-10 Taiho Pharmaceutical Co., Ltd. Kompozycja farmaceutyczna zawierająca alkilosiarczan sodu

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2837477A1 (de) * 1978-08-28 1980-03-13 Bayer Ag Sila-substituierte 1,4-dihydropyridin- derivate
JPS5547615A (en) * 1978-09-29 1980-04-04 Taiyo Yakuhin Kogyo Kk Stable solid drug of nifedipine
JPS56110612A (en) * 1980-02-08 1981-09-01 Yamanouchi Pharmaceut Co Ltd Readily disintegrable and absorbable compression molded article of slightly soluble drug
DE3142853A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen mit nifedipin und verfahren zu ihrer herstellung
DE3212736A1 (de) * 1982-04-06 1983-10-13 Bayer Ag, 5090 Leverkusen Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung
DE3307422A1 (de) * 1983-03-03 1984-09-06 Bayer Ag, 5090 Leverkusen Fluessigzubereitungen von dihydropyridinen, ein verfahren zu ihrer herstellung, sowie ihre verwendung bei der bekaempfung von erkrankungen

Also Published As

Publication number Publication date
KR920006909B1 (ko) 1992-08-22
AU578114B2 (en) 1988-10-13
GR852176B (es) 1986-01-10
JPS6168431A (ja) 1986-04-08
US4724141A (en) 1988-02-09
ZA856916B (en) 1986-04-30
DE3574933D1 (de) 1990-02-01
ES546799A0 (es) 1987-10-16
DK411485D0 (da) 1985-09-10
ATE48943T1 (de) 1990-01-15
EP0176773A1 (de) 1986-04-09
AU4733585A (en) 1986-03-20
EP0176773B1 (de) 1989-12-27
JPH0761960B2 (ja) 1995-07-05
IL76332A0 (en) 1986-01-31
DE3433239A1 (de) 1986-03-20
KR860002270A (ko) 1986-04-24
CA1261271A (en) 1989-09-26
DK411485A (da) 1986-03-12

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401