ES8706837A1 - Procedimiento para recemizar una n-benciliden-amida de aminoacido opticamente activa. - Google Patents

Procedimiento para recemizar una n-benciliden-amida de aminoacido opticamente activa.

Info

Publication number
ES8706837A1
ES8706837A1 ES553903A ES553903A ES8706837A1 ES 8706837 A1 ES8706837 A1 ES 8706837A1 ES 553903 A ES553903 A ES 553903A ES 553903 A ES553903 A ES 553903A ES 8706837 A1 ES8706837 A1 ES 8706837A1
Authority
ES
Spain
Prior art keywords
amino
acid amide
solution
acid
benzylidene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES553903A
Other languages
English (en)
Other versions
ES553903A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stamicarbon BV
Original Assignee
Stamicarbon BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stamicarbon BV filed Critical Stamicarbon BV
Publication of ES553903A0 publication Critical patent/ES553903A0/es
Publication of ES8706837A1 publication Critical patent/ES8706837A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Edible Oils And Fats (AREA)
  • Seeds, Soups, And Other Foods (AREA)

Abstract

METODO DE PREPARAR UNA AMIDA DE DI-AMINOACIDO A PARTIR DE UNA AMIDA DE AMINOACIDO OPTICAMENTE ACTIVA. CONSISTE EN: CONVERTIR UNA AMIDA DE AMINOACIDO OPTICAMENTE ACTIVA EN UNA AMINA DE N-BENCILIDEN-AMINOACIDO HACIENDOLA REACCIONAR CON UN BENZOALDEHIDO; SEPARARLA DE LA MEZCLA DE REACCION; DISOLVERLA EN UN DISOLVENTE ORGANICO MISCIBLE CON AGUA; MEZCLAR CON 0,05 MOLES DE UNA BASE FUERTE POR LITRO DE SOLUCION CON LO QUE SE PRODUCE LA RACEMIZACION DE LA AMIDA; CONVERTIR LA AMIDA DEL DL-N-BENCILIDEN-AMINOACIDO EN LA AMIDA DEL DL-AMINOACIDO LLEVANDO LA SOLUCION CON UN ACIDO A UN PH DE 3 A 7; Y CONVERTIR LA SAL DE AMIDA DE DL-AMINOACIDO FORMADO, EN UN MEDIO ACUOSO A PH DE 8 A 10, EN LA AMIDA DEL DL-AMINOACIDO. TIENE UTILIDAD PARA PREPARAR COMPOSICIONES FARMACEUTICAS.
ES553903A 1985-04-12 1986-04-11 Procedimiento para recemizar una n-benciliden-amida de aminoacido opticamente activa. Expired ES8706837A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8501093A NL8501093A (nl) 1985-04-12 1985-04-12 Werkwijze voor het racemiseren van een optisch aktief n- benzylideenaminozuuramide.

Publications (2)

Publication Number Publication Date
ES553903A0 ES553903A0 (es) 1987-07-01
ES8706837A1 true ES8706837A1 (es) 1987-07-01

Family

ID=19845833

Family Applications (1)

Application Number Title Priority Date Filing Date
ES553903A Expired ES8706837A1 (es) 1985-04-12 1986-04-11 Procedimiento para recemizar una n-benciliden-amida de aminoacido opticamente activa.

Country Status (13)

Country Link
US (2) US4847412A (es)
EP (1) EP0199407B1 (es)
JP (1) JPH0655702B2 (es)
AT (1) ATE50241T1 (es)
BR (1) BR8601656A (es)
CA (1) CA1292434C (es)
DE (1) DE3668883D1 (es)
DK (1) DK166986A (es)
ES (1) ES8706837A1 (es)
IL (1) IL78462A0 (es)
NL (1) NL8501093A (es)
PT (1) PT82379B (es)
ZA (1) ZA862746B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8501093A (nl) * 1985-04-12 1986-11-03 Stamicarbon Werkwijze voor het racemiseren van een optisch aktief n- benzylideenaminozuuramide.
EP0330695B1 (en) * 1987-08-17 1992-11-11 Novo Nordisk A/S Process for preparation of organic chemicals
NL8800260A (nl) * 1988-02-04 1989-09-01 Stamicarbon Alpha-n-hydroxyaminozuren, amiden en andere derivaten daarvan.
DE3816063A1 (de) * 1988-05-06 1989-11-23 Schering Ag Verfahren zur herstellung von l-aminosaeuren und aminosaeure-amiden
EP0383403A1 (en) * 1989-02-16 1990-08-22 Stamicarbon B.V. Process for preparation of organic chemicals
FR2655660B1 (fr) * 1989-12-11 1992-03-20 Rhone Poulenc Sante Nouveaux polypeptides, sequences d'adn permettant leur expression, procede de preparation et leur utilisation.
NL9000387A (nl) 1990-02-16 1991-09-16 Stamicarbon Werkwijze voor het racemiseren van een optisch aktief aminozuuramide.
FR2661909B1 (fr) * 1990-05-09 1997-08-14 Inst Nat Sante Rech Med Nouveaux composes agonistes du recepteur h3 de l'histamine a usage therapeutique, compositions pharmaceutiques agissant comme agonistes dudit recepteur et procede de preparation.
NL9201230A (nl) * 1992-07-09 1994-02-01 Dsm Nv Werkwijze voor de bereiding van optisch aktief methionineamide.
JPH08157437A (ja) * 1994-12-08 1996-06-18 Ajinomoto Co Inc Ｄ−アミノ酸−Ｎ−（Ｓ）−α−アルキルベンジルアミドの製造法
DE19529293A1 (de) * 1995-08-09 1997-02-13 Bayer Ag Verfahren zur Herstellung von racemischen Amino-Derivaten
HU226421B1 (en) * 1998-11-09 2008-12-29 Sanofi Aventis Process for racemizing optically active 2-(2-chlorophenyl)-2-(2-(2-thienyl)-ethylamino)-acetamides
NL1015495C2 (nl) * 2000-06-22 2001-12-28 Dsm Nv Werkwijze voor het racemiseren van een enantiomeer verrijkte schiffse base van een aminozuuramide.
NL1015715C2 (nl) * 2000-07-14 2002-01-17 Dsm Nv Werkwijze voor de bereiding van (schiffse basen van) alfa-alkyl-alfa-aminozuuramiden.
JP4879896B2 (ja) * 2005-07-29 2012-02-22 長瀬産業株式会社 アルジミンまたはその誘導体を用いる一置換アルキル化化合物の製造方法
CN101723773B (zh) * 2009-11-27 2011-09-21 天津大学 高纯度n-乙酰-dl-氨基酸的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US440792A (en) * 1890-11-18 Process of making hydrogen peroxide
US2945883A (en) * 1953-05-20 1960-07-19 Farmaceutici Italia Process for converting optically active aminodiols into racemic aminodiols by oxidation followed by racemization
BE795874A (fr) * 1972-02-25 1973-08-23 Glaxo Lab Ltd Procede de preparation d'esters optiquement actifs d'alpha-amino-acides
NL182954C (nl) * 1975-08-20 1988-06-16 Stamicarbon Werkwijze voor het bereiden van alfa-aminozuuramide.
NL7514300A (nl) * 1975-12-09 1977-06-13 Stamicarbon Werkwijze voor de bereiding van optisch actief fenylglycineamide.
NL187110C (nl) * 1976-11-10 1991-06-03 Stamicarbon Werkwijze voor het scheiden van een mengsel van een optisch aktief fenylglycine-amide en een optisch aktief fenylglycine.
NL188037C (nl) * 1977-11-30 1992-03-16 Stamicarbon Werkwijze voor de bereiding van dl-fenylglycine-amide via racemisatie.
FR2430413A1 (fr) * 1978-07-07 1980-02-01 Anvar Procede de preparation d'alpha-aminoacides optiquement actifs, et leurs derives
US4401820A (en) * 1981-01-23 1983-08-30 Tanabe Seiyaku Co., Ltd. Process for racemizing optically active α-amino acids or a salt thereof
FR2523961B1 (fr) * 1982-03-23 1985-08-30 Centre Nat Rech Scient Procede de preparation d'un alpha-amino-acide libre l
NL8501093A (nl) * 1985-04-12 1986-11-03 Stamicarbon Werkwijze voor het racemiseren van een optisch aktief n- benzylideenaminozuuramide.
US4713470A (en) * 1985-05-22 1987-12-15 Stauffer Chemical Company Racemization of amino acids

Also Published As

Publication number Publication date
ATE50241T1 (de) 1990-02-15
DK166986D0 (da) 1986-04-11
US4847412A (en) 1989-07-11
BR8601656A (pt) 1986-12-16
ES553903A0 (es) 1987-07-01
ZA862746B (en) 1986-11-26
EP0199407A1 (en) 1986-10-29
CA1292434C (en) 1991-11-26
JPH0655702B2 (ja) 1994-07-27
JPS61238770A (ja) 1986-10-24
DK166986A (da) 1986-10-13
EP0199407B1 (en) 1990-02-07
DE3668883D1 (de) 1990-03-15
IL78462A0 (en) 1986-08-31
NL8501093A (nl) 1986-11-03
PT82379A (en) 1986-05-01
PT82379B (en) 1987-09-10
US5047585A (en) 1991-09-10

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FD1A Patent lapsed

Effective date: 20050512