CS738585A2 - Zpusob vyroby l fenylalaninu a l tryptofanu - Google Patents

Zpusob vyroby l fenylalaninu a l tryptofanu

Info

Publication number
CS738585A2
CS738585A2 CS857385A CS738585A CS738585A2 CS 738585 A2 CS738585 A2 CS 738585A2 CS 857385 A CS857385 A CS 857385A CS 738585 A CS738585 A CS 738585A CS 738585 A2 CS738585 A2 CS 738585A2
Authority
CS
Czechoslovakia
Prior art keywords
tryptofanu
fenylalaninu
racemate
ester
extracted
Prior art date
Application number
CS857385A
Other languages
Czech (cs)
Other versions
CS258132B2 (en
Inventor
Reinhold Dr Keller
Merten Dr Schlingmann
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CS738585A2 publication Critical patent/CS738585A2/en
Publication of CS258132B2 publication Critical patent/CS258132B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1. A process for the preparation of aromatically substituted L-amino acids by enzymatic cleavage of the racemate of the lower alkyl esters (except tert.-butylester) using alpha-chymotrypsin in the weakly acid pH range and extraction of the ester of the D form, which comprises the reaction mixture obtained in the enzymatic cleavage being made weakly alkaline, the ester of the D-amino acid being extracted from this alkaline solution using an organic solvent, and being racemized, whereupon the racemate is returned to the process, and the extracted alkaline solution being made weakly acid, whereupon the L-amino acid is isolated from it.
CS857385A 1984-10-18 1985-10-16 Method of l-phenylalanine and l-tryphtofan production CS258132B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843438189 DE3438189A1 (en) 1984-10-18 1984-10-18 METHOD FOR PRODUCING AROMATICALLY SUBSTITUTED L-AMINO ACIDS

Publications (2)

Publication Number Publication Date
CS738585A2 true CS738585A2 (en) 1987-12-17
CS258132B2 CS258132B2 (en) 1988-07-15

Family

ID=6248201

Family Applications (1)

Application Number Title Priority Date Filing Date
CS857385A CS258132B2 (en) 1984-10-18 1985-10-16 Method of l-phenylalanine and l-tryphtofan production

Country Status (15)

Country Link
EP (1) EP0178553B1 (en)
JP (1) JPS61108398A (en)
AT (1) ATE56472T1 (en)
CA (1) CA1265083A (en)
CS (1) CS258132B2 (en)
DE (2) DE3438189A1 (en)
DK (1) DK475585A (en)
ES (1) ES8609186A1 (en)
FI (1) FI854025L (en)
GR (1) GR852491B (en)
HU (1) HUT39414A (en)
IL (1) IL76740A0 (en)
NO (1) NO854127L (en)
PT (1) PT81320B (en)
ZA (1) ZA857971B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3618465A1 (en) * 1986-06-02 1987-12-03 Hoechst Ag CARRYING OUT BIO CATALYST REACTIONS IN A FLUID BED REACTOR WITH A 2-PHASE LIQUID SYSTEM
DE3622662A1 (en) * 1986-07-05 1988-01-14 Hoechst Ag METHOD FOR CONTINUOUS BIOCATALYTIC IMPLEMENTATION OF SUBSTRATES WHICH ARE SLIGHTLY SOLUBLE IN AQUEOUS SOLUTIONS
US5002871A (en) * 1986-08-18 1991-03-26 The Coca-Cola Company Enzymatic membrane method for the synthesis and separation of peptides
DE3839379A1 (en) * 1988-11-22 1990-05-23 Hoechst Ag METHOD FOR PRODUCING TRIPEPTIDES
US5025325A (en) * 1989-10-13 1991-06-18 Hewlett-Packard Company Graphics scaling method for high resolution printers
DE19546532C2 (en) * 1995-12-13 2000-04-20 Degussa Process for obtaining optically active L-alpha-aminocarboxylic acids from corresponding racemic D, L-alpha-aminocarboxylic acids
FR2778671B1 (en) * 1998-05-14 2002-07-05 Rhone Poulenc Agrochimie NEW PROCESS FOR THE PREPARATION OF SYNTHESIS INTERMEDIATES
DK1434870T3 (en) 2001-09-25 2007-04-30 Hoffmann La Roche Enzymatic process for preparing substituted 2-amino-3- (2-amino-phenylsulfanyl) -propionic acid
JP5028672B2 (en) * 2007-05-23 2012-09-19 ボイス パテント ゲーエムベーハー Waste paper cutting rotor
JP4934881B2 (en) * 2007-05-23 2012-05-23 ボイス パテント ゲーエムベーハー Waste paper cutting rotor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA947214A (en) * 1971-04-02 1974-05-14 Antoine D'iorio Resolution of racemates of ring-substituted phenylalanines
US3878043A (en) * 1973-01-02 1975-04-15 Univ Southern Illinois Method for preparing L-dopa and novels compounds useful therein

Also Published As

Publication number Publication date
NO854127L (en) 1986-04-21
EP0178553B1 (en) 1990-09-12
FI854025L (en) 1986-04-19
HUT39414A (en) 1986-09-29
PT81320B (en) 1987-05-18
DE3438189A1 (en) 1986-04-24
DK475585A (en) 1986-04-19
ATE56472T1 (en) 1990-09-15
ZA857971B (en) 1986-05-28
IL76740A0 (en) 1986-02-28
CS258132B2 (en) 1988-07-15
DK475585D0 (en) 1985-10-17
FI854025A0 (en) 1985-10-16
EP0178553A2 (en) 1986-04-23
DE3579663D1 (en) 1990-10-18
GR852491B (en) 1986-02-11
ES8609186A1 (en) 1986-09-01
ES547901A0 (en) 1986-09-01
EP0178553A3 (en) 1987-04-29
JPS61108398A (en) 1986-05-27
PT81320A (en) 1985-11-01
CA1265083A (en) 1990-01-30

Similar Documents

Publication Publication Date Title
EP0353248A4 (en) Method for resolution of stereoisomers in multiphase and extractive membrane reactors
DE69833469D1 (en) Process for the preparation of L-amino acids by fermentation
FR2626288B1 (en)
CS738585A2 (en) Zpusob vyroby l fenylalaninu a l tryptofanu
DE59106289D1 (en) Process for the preparation of salts of L-ornithine.
DE3668883D1 (en) METHOD FOR RACEMIZING AN OPTICALLY ACTIVE N-BENZYLIDENAMINOAIDAMID.
GB8715476D0 (en) Preparation of ibuprofen
ES8700862A1 (en) Production of A-21978C derivatives.
DE3562369D1 (en) Extraction of amino acid from aqueous mixtures
ATE2441T1 (en) PROCESS FOR THE ENZYMATIC PRODUCTION OF ALDON ACIDS.
DE68912236D1 (en) Process for the production of highly unsaturated fatty acids.
ATE42203T1 (en) SEMI-SYNTHETIC PROCESS FOR THE MANUFACTURE OF INSULIN.
EP0321849A3 (en) Method for the enzymatic hydrolysis of alpha-aminoadipinyl monoamino compounds
GB1497992A (en) Production of carboxy-alkane-phosphonic acids and carboxy-alkyl-phosphinic acids
DE3782184D1 (en) METHOD FOR THE FERMENTATIVE PRODUCTION OF L-AMINO ACIDS FROM ALPHA KETOCARBONIC ACIDS.
EP0155165A3 (en) Process for introducing phosphinoyl groups into amino groups
EP0310948A3 (en) Process for the preparation of optically pure phenyl ring-substituted phenyl alamine derivatives
HUT52802A (en) Process for production of polimer polielectrolits
ES2019166A6 (en) Process for the enzymic resolution of optically active isomers of methyl esters of N-substituted amino acids