IL76740A0 - Process for the preparation of aromatically substituted l-amino acids - Google Patents

Process for the preparation of aromatically substituted l-amino acids

Info

Publication number
IL76740A0
IL76740A0 IL76740A IL7674085A IL76740A0 IL 76740 A0 IL76740 A0 IL 76740A0 IL 76740 A IL76740 A IL 76740A IL 7674085 A IL7674085 A IL 7674085A IL 76740 A0 IL76740 A0 IL 76740A0
Authority
IL
Israel
Prior art keywords
preparation
amino acids
aromatically substituted
racemate
ester
Prior art date
Application number
IL76740A
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL76740A0 publication Critical patent/IL76740A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1. A process for the preparation of aromatically substituted L-amino acids by enzymatic cleavage of the racemate of the lower alkyl esters (except tert.-butylester) using alpha-chymotrypsin in the weakly acid pH range and extraction of the ester of the D form, which comprises the reaction mixture obtained in the enzymatic cleavage being made weakly alkaline, the ester of the D-amino acid being extracted from this alkaline solution using an organic solvent, and being racemized, whereupon the racemate is returned to the process, and the extracted alkaline solution being made weakly acid, whereupon the L-amino acid is isolated from it.
IL76740A 1984-10-18 1985-10-17 Process for the preparation of aromatically substituted l-amino acids IL76740A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843438189 DE3438189A1 (en) 1984-10-18 1984-10-18 METHOD FOR PRODUCING AROMATICALLY SUBSTITUTED L-AMINO ACIDS

Publications (1)

Publication Number Publication Date
IL76740A0 true IL76740A0 (en) 1986-02-28

Family

ID=6248201

Family Applications (1)

Application Number Title Priority Date Filing Date
IL76740A IL76740A0 (en) 1984-10-18 1985-10-17 Process for the preparation of aromatically substituted l-amino acids

Country Status (15)

Country Link
EP (1) EP0178553B1 (en)
JP (1) JPS61108398A (en)
AT (1) ATE56472T1 (en)
CA (1) CA1265083A (en)
CS (1) CS258132B2 (en)
DE (2) DE3438189A1 (en)
DK (1) DK475585A (en)
ES (1) ES8609186A1 (en)
FI (1) FI854025L (en)
GR (1) GR852491B (en)
HU (1) HUT39414A (en)
IL (1) IL76740A0 (en)
NO (1) NO854127L (en)
PT (1) PT81320B (en)
ZA (1) ZA857971B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3618465A1 (en) * 1986-06-02 1987-12-03 Hoechst Ag CARRYING OUT BIO CATALYST REACTIONS IN A FLUID BED REACTOR WITH A 2-PHASE LIQUID SYSTEM
DE3622662A1 (en) * 1986-07-05 1988-01-14 Hoechst Ag METHOD FOR CONTINUOUS BIOCATALYTIC IMPLEMENTATION OF SUBSTRATES WHICH ARE SLIGHTLY SOLUBLE IN AQUEOUS SOLUTIONS
US5002871A (en) * 1986-08-18 1991-03-26 The Coca-Cola Company Enzymatic membrane method for the synthesis and separation of peptides
DE3839379A1 (en) * 1988-11-22 1990-05-23 Hoechst Ag METHOD FOR PRODUCING TRIPEPTIDES
US5025325A (en) * 1989-10-13 1991-06-18 Hewlett-Packard Company Graphics scaling method for high resolution printers
DE19546532C2 (en) * 1995-12-13 2000-04-20 Degussa Process for obtaining optically active L-alpha-aminocarboxylic acids from corresponding racemic D, L-alpha-aminocarboxylic acids
FR2778671B1 (en) 1998-05-14 2002-07-05 Rhone Poulenc Agrochimie NEW PROCESS FOR THE PREPARATION OF SYNTHESIS INTERMEDIATES
ES2278061T3 (en) 2001-09-25 2007-08-01 F. Hoffmann-La Roche Ag ENZYMATIC PROCESS FOR PREPARATION OF ACID 2-AMINO-3- (2-AMINO-PHENYL SULFANIL) -PROPIONIC SUBSTITUTED.
JP5028672B2 (en) * 2007-05-23 2012-09-19 ボイス パテント ゲーエムベーハー Waste paper cutting rotor
JP4934881B2 (en) * 2007-05-23 2012-05-23 ボイス パテント ゲーエムベーハー Waste paper cutting rotor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA947214A (en) * 1971-04-02 1974-05-14 Antoine D'iorio Resolution of racemates of ring-substituted phenylalanines
US3878043A (en) * 1973-01-02 1975-04-15 Univ Southern Illinois Method for preparing L-dopa and novels compounds useful therein

Also Published As

Publication number Publication date
EP0178553A2 (en) 1986-04-23
ES8609186A1 (en) 1986-09-01
DK475585D0 (en) 1985-10-17
EP0178553B1 (en) 1990-09-12
NO854127L (en) 1986-04-21
DE3579663D1 (en) 1990-10-18
CA1265083A (en) 1990-01-30
DE3438189A1 (en) 1986-04-24
ES547901A0 (en) 1986-09-01
EP0178553A3 (en) 1987-04-29
HUT39414A (en) 1986-09-29
CS738585A2 (en) 1987-12-17
PT81320A (en) 1985-11-01
PT81320B (en) 1987-05-18
FI854025A0 (en) 1985-10-16
GR852491B (en) 1986-02-11
ZA857971B (en) 1986-05-28
DK475585A (en) 1986-04-19
FI854025L (en) 1986-04-19
CS258132B2 (en) 1988-07-15
JPS61108398A (en) 1986-05-27
ATE56472T1 (en) 1990-09-15

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