ES8706792A1 - Procedimiento de exaltacion de la fluorescencia de un ion detierra rara - Google Patents
Procedimiento de exaltacion de la fluorescencia de un ion detierra raraInfo
- Publication number
- ES8706792A1 ES8706792A1 ES547294A ES547294A ES8706792A1 ES 8706792 A1 ES8706792 A1 ES 8706792A1 ES 547294 A ES547294 A ES 547294A ES 547294 A ES547294 A ES 547294A ES 8706792 A1 ES8706792 A1 ES 8706792A1
- Authority
- ES
- Spain
- Prior art keywords
- rare earth
- application
- earth metals
- fluorescent labels
- macropolycyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910052761 rare earth metal Inorganic materials 0.000 title abstract 2
- 150000002910 rare earth metals Chemical class 0.000 title abstract 2
Classifications
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
- C09K11/08—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials
- C09K11/77—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/40—Rare earth chelates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Materials Engineering (AREA)
- Inorganic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Luminescent Compositions (AREA)
- Steroid Compounds (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
METODO DE EXALTACION DE LA FLUORESCENCIA DE UN ION DE TIERRA RARA. CONSISTE EN COMPLEJAR UN ION DE TIERRA RARA CON UN COMPUESTO MACROPOLICICLICO DE FORMULA (I) EN LA QUE Z ES UN ATOMO DE 3 O 4 VALENCIAS; R ES NADA O REPERESENTA H, EL GRUPO HIDROXI, UN GRUPO AMINO O UN RADICAL HIDROCARBONADO; LOS RADICALES (A), (B) Y (C), SON INDEPENDIENTEMENTE UNO DEL OTRO CADENAS HIDROCARBONADAS QUE CONTIENEN EVENTUALMENTE UNO O VARIOS HETEROATOMOS Y QUE ESTAN EVENTUALMENTE INTERRUMPIDAS POR UN HETEROMACROCICLO; Y EXCITAR EL MOTIVO DONADOR DEL COMPUESTO DE FORMULA (I). TIENEN APLICACION COMO MARCADORES EN LOS DOSIFICADOS INMUNOLOGICOS. *FORMULA*
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8414799A FR2570703B1 (fr) | 1984-09-26 | 1984-09-26 | Complexes macropolycycliques de terres rares et application a titre de marqueurs fluorescents |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8706792A1 true ES8706792A1 (es) | 1987-07-01 |
ES547294A0 ES547294A0 (es) | 1987-07-01 |
Family
ID=9308106
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES547294A Expired ES8706792A1 (es) | 1984-09-26 | 1985-09-25 | Procedimiento de exaltacion de la fluorescencia de un ion detierra rara |
ES557485A Expired ES8801695A1 (es) | 1984-09-26 | 1987-04-01 | Procedimiento de obtencion de complejos macropoliciclicos de tierras ratas |
ES557486A Expired ES8801938A1 (es) | 1984-09-26 | 1987-04-01 | Procedimiento para la obtencion de comopuestos macropoliciclicos |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES557485A Expired ES8801695A1 (es) | 1984-09-26 | 1987-04-01 | Procedimiento de obtencion de complejos macropoliciclicos de tierras ratas |
ES557486A Expired ES8801938A1 (es) | 1984-09-26 | 1987-04-01 | Procedimiento para la obtencion de comopuestos macropoliciclicos |
Country Status (9)
Country | Link |
---|---|
US (1) | US4927923A (es) |
EP (1) | EP0180492B1 (es) |
JP (3) | JPH0655741B2 (es) |
KR (1) | KR930008210B1 (es) |
AT (1) | ATE90084T1 (es) |
CA (1) | CA1329593C (es) |
DE (1) | DE3587380T2 (es) |
ES (3) | ES8706792A1 (es) |
FR (1) | FR2570703B1 (es) |
Families Citing this family (99)
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US5220012A (en) * | 1984-09-26 | 1993-06-15 | Compagnie Oris Industrie Sa | Macropolycyclic rare earth complexes and application as fluorescent tracers |
SE454781B (sv) * | 1986-10-17 | 1988-05-30 | Wallac Oy | Hybridiseringsforfarande for detektion av polynukleotidsekvens |
FR2624862B1 (fr) * | 1987-12-18 | 1990-06-08 | Oris Ind | Cryptates de terres rares, procedes d'obtention, intermediaires de synthese et application a titre de marqueurs fluorescents |
US5162508A (en) * | 1987-12-18 | 1992-11-10 | Compagnie Oris Industrie | Rare earth cryptates, processes for their preparation, synthesis intermediates and application as fluorescent tracers |
US5134232A (en) * | 1988-11-14 | 1992-07-28 | The Regents Of The University Of California | Fluorescent indicator dyes for alkali metal cations |
US5094759A (en) * | 1989-03-17 | 1992-03-10 | The University Of Southern Mississippi | Method of water treatment using 2,6-substituted aminopyridines and polymer derived therefrom |
US5216134A (en) * | 1989-10-23 | 1993-06-01 | Wallac Oy | Spectrofluorometric method and compounds that are of value for the method |
FR2664699B1 (fr) * | 1990-07-13 | 1995-08-18 | Cis Bio Int | Procede d'amplification du signal d'emission d'un compose luminescent. |
EP0554358A4 (en) * | 1990-09-27 | 1995-09-06 | Brunswick Corp | Chelating agents |
EP0493745A1 (en) * | 1990-12-21 | 1992-07-08 | Dojindo Laboratories | Fluorescent compound, complex, reagent, and specific binding assay employing said reagent |
CA2072934C (en) * | 1991-07-19 | 2007-08-28 | Karl William Aston | Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
FR2680787B1 (fr) * | 1991-08-30 | 1994-11-04 | Cis Bio Int | Complexes macrocycliques de terres rares et leur utilisation pour reduire les interferences dans un dosage par fluorescence. |
WO1993011433A1 (en) * | 1991-12-05 | 1993-06-10 | Wallac Oy | Luminescent lanthanide chelates |
US5417959A (en) * | 1993-10-04 | 1995-05-23 | Mallinckrodt Medical, Inc. | Functionalized aza-crytand ligands for diagnostic imaging applications |
WO1995020353A1 (en) * | 1994-01-28 | 1995-08-03 | Mallinckrodt Medical, Inc. | Functionalized aza-bimacrocyclic ligands for imaging applications |
US6017496A (en) | 1995-06-07 | 2000-01-25 | Irori | Matrices with memories and uses thereof |
US6329139B1 (en) | 1995-04-25 | 2001-12-11 | Discovery Partners International | Automated sorting system for matrices with memory |
US5792330A (en) * | 1995-05-31 | 1998-08-11 | Board Of Regents, The University Of Texas System | Lanthanide metal cations for concurrent detection and separation in capillary electrophoresis |
FR2768817B1 (fr) * | 1997-09-19 | 1999-12-10 | Cis Bio Int | Methode homogene pour la detection et/ou la determination de l'activite phosphorylante d'un materiel biologique |
FR2769315B1 (fr) * | 1997-10-03 | 2001-06-08 | Cis Bio Int | Conjugues fluorescents de nucleosides ou de nucleotides, leur procede de preparation et leur utilisation |
EP1925320A3 (en) | 1998-03-27 | 2008-09-03 | Prolume, Ltd. | Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics |
DE69938293T2 (de) | 1998-03-27 | 2009-03-12 | Bruce J. Beverly Hills Bryan | Luciferase, gfp fluoreszenzproteine, kodierende nukleinsaüre und ihre verwendung in der diagnose |
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CA966127A (en) * | 1970-05-12 | 1975-04-15 | Marilyn H. Bromels | Macrocyclic hetero imine complexing agents |
US4156683A (en) * | 1973-03-26 | 1979-05-29 | Schering Corporation | Complexes of macrocyclic compounds |
US3966766A (en) * | 1973-03-26 | 1976-06-29 | Schering Corporation | Monocyclic macrocyclic compounds and complexes thereof |
US4058732A (en) * | 1975-06-30 | 1977-11-15 | Analytical Radiation Corporation | Method and apparatus for improved analytical fluorescent spectroscopy |
SE428332B (sv) * | 1979-03-08 | 1983-06-20 | Wallac Oy | Forfarande for fluorescensspektroskopisk bestemning av biologiskt aktivt emne, sasom hapten, antikropp eller antigen |
US4352751A (en) * | 1979-09-10 | 1982-10-05 | Analytical Radiation Corporation | Species-linked diamine triacetic acids and their chelates |
CA1205028A (en) * | 1981-07-01 | 1986-05-27 | Jerald C. Hinshaw | Fluorescent chelates and labeled specific binding reagents prepared therefrom |
DE3202779A1 (de) * | 1982-01-28 | 1983-08-04 | Merck Patent Gmbh, 6100 Darmstadt | Kaliumreagens und verfahren zur bestimmung von kaliumionen |
US4631119A (en) * | 1983-11-23 | 1986-12-23 | W. R. Grace & Co. | Reversible, electrochemically-switched lariat ethers |
US4734376A (en) * | 1985-02-04 | 1988-03-29 | The President & Trustees Of The Miami University | Process for the spectrophotometric measurement of lithium ion employing a chromogenic aza-12-crown-4- ether |
US4659815A (en) * | 1985-02-04 | 1987-04-21 | The President And Trustees Of The Miami University | Chromogenic aza-12-crown-4 ethers and method of using same for the detection of lithium |
GB8528804D0 (en) * | 1985-11-22 | 1985-12-24 | Amersham Int Plc | Compounds |
-
1984
- 1984-09-26 FR FR8414799A patent/FR2570703B1/fr not_active Expired
-
1985
- 1985-09-20 US US06/778,215 patent/US4927923A/en not_active Expired - Lifetime
- 1985-09-23 CA CA000491360A patent/CA1329593C/en not_active Expired - Lifetime
- 1985-09-23 EP EP85401838A patent/EP0180492B1/fr not_active Expired - Lifetime
- 1985-09-23 DE DE85401838T patent/DE3587380T2/de not_active Expired - Lifetime
- 1985-09-23 AT AT85401838T patent/ATE90084T1/de not_active IP Right Cessation
- 1985-09-25 ES ES547294A patent/ES8706792A1/es not_active Expired
- 1985-09-26 JP JP60213587A patent/JPH0655741B2/ja not_active Expired - Lifetime
- 1985-09-26 KR KR1019850007109A patent/KR930008210B1/ko not_active IP Right Cessation
-
1987
- 1987-04-01 ES ES557485A patent/ES8801695A1/es not_active Expired
- 1987-04-01 ES ES557486A patent/ES8801938A1/es not_active Expired
-
1993
- 1993-07-02 JP JP16372993A patent/JPH0714935B2/ja not_active Expired - Lifetime
- 1993-07-02 JP JP16373093A patent/JPH0715471B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES8801695A1 (es) | 1988-02-16 |
JPH06184151A (ja) | 1994-07-05 |
EP0180492A1 (fr) | 1986-05-07 |
DE3587380D1 (es) | 1993-07-08 |
CA1329593C (en) | 1994-05-17 |
JPH0714935B2 (ja) | 1995-02-22 |
ES557486A0 (es) | 1988-03-01 |
FR2570703A1 (fr) | 1986-03-28 |
FR2570703B1 (fr) | 1988-07-08 |
JPH0655741B2 (ja) | 1994-07-27 |
ES557485A0 (es) | 1988-02-16 |
KR860002553A (ko) | 1986-04-26 |
ES547294A0 (es) | 1987-07-01 |
JPS6187680A (ja) | 1986-05-06 |
JPH06199858A (ja) | 1994-07-19 |
JPH0715471B2 (ja) | 1995-02-22 |
DE3587380T2 (de) | 1994-01-05 |
ATE90084T1 (de) | 1993-06-15 |
KR930008210B1 (ko) | 1993-08-26 |
EP0180492B1 (fr) | 1993-06-02 |
US4927923A (en) | 1990-05-22 |
ES8801938A1 (es) | 1988-03-01 |
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Legal Events
Date | Code | Title | Description |
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FD1A | Patent lapsed |
Effective date: 20070514 |