ES8704907A1 - Un procedimiento para preparar derivados de 4h-1,2,4-triazol - Google Patents

Un procedimiento para preparar derivados de 4h-1,2,4-triazol

Info

Publication number
ES8704907A1
ES8704907A1 ES547209A ES547209A ES8704907A1 ES 8704907 A1 ES8704907 A1 ES 8704907A1 ES 547209 A ES547209 A ES 547209A ES 547209 A ES547209 A ES 547209A ES 8704907 A1 ES8704907 A1 ES 8704907A1
Authority
ES
Spain
Prior art keywords
formula
see diagramm
radical
carbon atoms
alkyl radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES547209A
Other languages
English (en)
Other versions
ES547209A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES8704907A1 publication Critical patent/ES8704907A1/es
Publication of ES547209A0 publication Critical patent/ES547209A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Packaging Of Special Articles (AREA)
  • Signal Processing For Digital Recording And Reproducing (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEIDMIENTO PARA PREPARAR DERIVADOS DE 4H-1,2,4-TRIAZOL. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN AGENTE DE CLORURACION PARA OBTENER UN CLORURO DE IMIDOILO DE FORMULA (III); HACER REACCIONAR EL COMPUESTO DE FORMULA (III) OBTENIDO CON UNA HIDRAZINA DE FORMULA (IV) PARA OBTENER UN COMPUESTO DE FORMULA (V), EN FORMA RACEMICA U OPTICAMENTE ACTIVA; Y CICLAR POR CALENTAMIENTO EL COMPUESTO DE FORMULA (V) PARA OBTENER DERIVADOS DE 4H-1,2,4-TRIAZOL DE FORMULA (I) DONDE R1, R2, R3 Y R4, IGUALES O DIFERENTES, SON UN ATOMO DE H, UN RADICAL HIDROXILO Y OTROS; Y R ES UN RADICAL ALQUILO CON C 1 A 4, UN RADICAL CHOH-ALC4 Y OTROS. SON UTILES EN FARMACIA POR SU ACTIVIDAD ANALGESICA.
ES547209A 1984-09-24 1985-09-23 Un procedimiento para preparar derivados de 4h-1,2,4-triazol Expired ES8704907A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8414598A FR2570699B1 (fr) 1984-09-24 1984-09-24 Nouveau procede de preparation de derives du 4h-1,2,4-triazole, nouveaux triazoles ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les renfermant

Publications (2)

Publication Number Publication Date
ES8704907A1 true ES8704907A1 (es) 1987-04-16
ES547209A0 ES547209A0 (es) 1987-04-16

Family

ID=9307987

Family Applications (1)

Application Number Title Priority Date Filing Date
ES547209A Expired ES8704907A1 (es) 1984-09-24 1985-09-23 Un procedimiento para preparar derivados de 4h-1,2,4-triazol

Country Status (16)

Country Link
EP (1) EP0176444B1 (es)
JP (1) JPS6185370A (es)
AT (1) ATE40886T1 (es)
AU (1) AU585895B2 (es)
CA (1) CA1256113A (es)
DE (1) DE3568331D1 (es)
DK (1) DK429085A (es)
ES (1) ES8704907A1 (es)
FI (1) FI86178C (es)
FR (1) FR2570699B1 (es)
GR (1) GR852310B (es)
HU (1) HU194188B (es)
IE (1) IE58497B1 (es)
OA (1) OA08105A (es)
PT (1) PT81180B (es)
ZA (1) ZA857294B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8429307D0 (en) * 1984-11-20 1984-12-27 Shell Int Research Heterocyclic herbicides
CA2067742A1 (en) * 1990-08-22 1992-02-23 Tetsuo Takematsu N-acyl-n-phenyltetrahydrophthalamic acid derivatives methods of producing same, and herbicides containing same as effective components
US5523325A (en) * 1993-09-09 1996-06-04 Jacobson; Richard M. Amidrazones and their use as pesticides
KR100470076B1 (ko) 2002-11-27 2005-02-05 씨제이 주식회사 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물
AU2008315757A1 (en) * 2007-10-24 2009-04-30 Generics [Uk] Limited Novel crystalline forms

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2884424A (en) * 1957-11-18 1959-04-28 American Cyanamid Co Production of triazoles and amidrazones of the anthraquinone series
FR2244462A1 (en) * 1973-09-25 1975-04-18 Delalande Sa Antihypertensive, 5-hydroxy methyl 1,2,4-triazoles - prepd. from aniline and a hydroxy methyl 1,3,4-oxadiazole
FR2269938A2 (en) * 1974-05-08 1975-12-05 Delalande Sa 5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc.
GB1510647A (en) * 1975-10-10 1978-05-10 Commw Scient Ind Res Org Triazoles
FR2488891A1 (fr) * 1980-08-22 1982-02-26 Roussel Uclaf Nouveaux derives du 4h-1,2,4-triazole, leur procede de preparation et leur application comme medicament
FR2512022A2 (fr) * 1980-08-22 1983-03-04 Roussel Uclaf Nouveaux derives du 4h-1,2,4-triazole, leur procede de preparation et leur application comme medicament
FR2539127B1 (fr) * 1983-01-10 1985-08-23 Roussel Uclaf Nouveaux derives du 4h-1,2,4-triazole, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
HUT40090A (en) 1986-11-28
ATE40886T1 (de) 1989-03-15
FR2570699A1 (fr) 1986-03-28
CA1256113A (fr) 1989-06-20
IE58497B1 (en) 1993-10-06
FI86178C (fi) 1992-07-27
DK429085D0 (da) 1985-09-23
EP0176444B1 (fr) 1989-02-22
AU4784085A (en) 1986-04-10
FR2570699B1 (fr) 1987-08-28
FI853643L (fi) 1986-03-25
PT81180A (fr) 1985-10-01
FI853643A0 (fi) 1985-09-23
EP0176444A1 (fr) 1986-04-02
ZA857294B (en) 1986-11-26
DE3568331D1 (en) 1989-03-30
OA08105A (fr) 1987-03-31
PT81180B (pt) 1988-01-22
IE852338L (en) 1986-03-24
ES547209A0 (es) 1987-04-16
AU585895B2 (en) 1989-06-29
JPS6185370A (ja) 1986-04-30
GR852310B (es) 1986-01-24
FI86178B (fi) 1992-04-15
DK429085A (da) 1986-03-25
HU194188B (en) 1988-01-28

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971103