DE3568331D1 - Process for the preparation of derivatives of 4h-1,2,4-triazole, triazoles so obtained, their use as medicaments, and pharmaceutical compositons containing them - Google Patents

Process for the preparation of derivatives of 4h-1,2,4-triazole, triazoles so obtained, their use as medicaments, and pharmaceutical compositons containing them

Info

Publication number
DE3568331D1
DE3568331D1 DE8585401844T DE3568331T DE3568331D1 DE 3568331 D1 DE3568331 D1 DE 3568331D1 DE 8585401844 T DE8585401844 T DE 8585401844T DE 3568331 T DE3568331 T DE 3568331T DE 3568331 D1 DE3568331 D1 DE 3568331D1
Authority
DE
Germany
Prior art keywords
formula
see diagramm
radical
carbon atoms
alkyl radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8585401844T
Other languages
English (en)
Inventor
Francois Clemence
Claudine Maushart
Philippe Mackiewicz
Francoise Delevallee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of DE3568331D1 publication Critical patent/DE3568331D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Packaging Of Special Articles (AREA)
  • Signal Processing For Digital Recording And Reproducing (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8585401844T 1984-09-24 1985-09-23 Process for the preparation of derivatives of 4h-1,2,4-triazole, triazoles so obtained, their use as medicaments, and pharmaceutical compositons containing them Expired DE3568331D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8414598A FR2570699B1 (fr) 1984-09-24 1984-09-24 Nouveau procede de preparation de derives du 4h-1,2,4-triazole, nouveaux triazoles ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
DE3568331D1 true DE3568331D1 (en) 1989-03-30

Family

ID=9307987

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585401844T Expired DE3568331D1 (en) 1984-09-24 1985-09-23 Process for the preparation of derivatives of 4h-1,2,4-triazole, triazoles so obtained, their use as medicaments, and pharmaceutical compositons containing them

Country Status (16)

Country Link
EP (1) EP0176444B1 (de)
JP (1) JPS6185370A (de)
AT (1) ATE40886T1 (de)
AU (1) AU585895B2 (de)
CA (1) CA1256113A (de)
DE (1) DE3568331D1 (de)
DK (1) DK429085A (de)
ES (1) ES8704907A1 (de)
FI (1) FI86178C (de)
FR (1) FR2570699B1 (de)
GR (1) GR852310B (de)
HU (1) HU194188B (de)
IE (1) IE58497B1 (de)
OA (1) OA08105A (de)
PT (1) PT81180B (de)
ZA (1) ZA857294B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8429307D0 (en) * 1984-11-20 1984-12-27 Shell Int Research Heterocyclic herbicides
DE69119884T2 (de) * 1990-08-22 1996-10-02 Central Glass Co Ltd Derivate der n-acyl-n-phenyltetrahydrophthalamsäure, ihre herstellung und herbizide die diese als aktive inhaltsstoffe enthalten
US5523325A (en) * 1993-09-09 1996-06-04 Jacobson; Richard M. Amidrazones and their use as pesticides
KR100470076B1 (ko) 2002-11-27 2005-02-05 씨제이 주식회사 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물
US8530488B2 (en) * 2007-10-24 2013-09-10 Generics [Uk] Limited Crystalline forms of bosentan

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2884424A (en) * 1957-11-18 1959-04-28 American Cyanamid Co Production of triazoles and amidrazones of the anthraquinone series
FR2244462A1 (en) * 1973-09-25 1975-04-18 Delalande Sa Antihypertensive, 5-hydroxy methyl 1,2,4-triazoles - prepd. from aniline and a hydroxy methyl 1,3,4-oxadiazole
FR2269938A2 (en) * 1974-05-08 1975-12-05 Delalande Sa 5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc.
GB1510647A (en) * 1975-10-10 1978-05-10 Commw Scient Ind Res Org Triazoles
FR2488891A1 (fr) * 1980-08-22 1982-02-26 Roussel Uclaf Nouveaux derives du 4h-1,2,4-triazole, leur procede de preparation et leur application comme medicament
FR2512022A2 (fr) * 1980-08-22 1983-03-04 Roussel Uclaf Nouveaux derives du 4h-1,2,4-triazole, leur procede de preparation et leur application comme medicament
FR2539127B1 (fr) * 1983-01-10 1985-08-23 Roussel Uclaf Nouveaux derives du 4h-1,2,4-triazole, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
OA08105A (fr) 1987-03-31
ES8704907A1 (es) 1987-04-16
HUT40090A (en) 1986-11-28
DK429085A (da) 1986-03-25
JPS6185370A (ja) 1986-04-30
DK429085D0 (da) 1985-09-23
ZA857294B (en) 1986-11-26
GR852310B (de) 1986-01-24
EP0176444A1 (de) 1986-04-02
ES547209A0 (es) 1987-04-16
FI853643L (fi) 1986-03-25
EP0176444B1 (de) 1989-02-22
FI86178B (fi) 1992-04-15
AU585895B2 (en) 1989-06-29
PT81180A (fr) 1985-10-01
FI853643A0 (fi) 1985-09-23
AU4784085A (en) 1986-04-10
IE852338L (en) 1986-03-24
FI86178C (fi) 1992-07-27
IE58497B1 (en) 1993-10-06
ATE40886T1 (de) 1989-03-15
FR2570699B1 (fr) 1987-08-28
HU194188B (en) 1988-01-28
FR2570699A1 (fr) 1986-03-28
CA1256113A (fr) 1989-06-20
PT81180B (pt) 1988-01-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee