ES8403129A1 - Procedimiento para la preparacion de nuevas tienobenzodiazepinonas sustituidas. - Google Patents

Procedimiento para la preparacion de nuevas tienobenzodiazepinonas sustituidas.

Info

Publication number
ES8403129A1
ES8403129A1 ES519529A ES519529A ES8403129A1 ES 8403129 A1 ES8403129 A1 ES 8403129A1 ES 519529 A ES519529 A ES 519529A ES 519529 A ES519529 A ES 519529A ES 8403129 A1 ES8403129 A1 ES 8403129A1
Authority
ES
Spain
Prior art keywords
methyl
preparing
medicines containing
pyridinyl
tetrahydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES519529A
Other languages
English (en)
Other versions
ES519529A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES519529A0 publication Critical patent/ES519529A0/es
Publication of ES8403129A1 publication Critical patent/ES8403129A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE TIENOBENZODIAZEPINONAS SUSTITUIDAS, DE FORMULA GENERAL (I), EN LA QUE R1 SIGNIFICA UN ATOMO DE HIDROGENO O UN GRUPO ALCOHILO CON 1 HASTA 4 ATOMOS DE CARBONO; R2 SIGNIFICA UN ATOMO DE HIDROGENO O DE HALOGENO O UN GRUPO ALCOHILO; Y R SIGNIFICA UN GRUPO (1-METIL-4-PIPERIDINIL)METILO O (1-METIL-1,2,5,6-TETRAHID RO-4-PIRIDINIL)METILO, Y SUS SALES POR ADICION CON ACIDOS INORGANICOS U ORGANICOS.CONSISTE EN ACILAR TIENOBENZODIAZEPINONAS, DE FORMULA GENERAL (II), EN LA QUE R1 Y R2 TIENEN LOS SIGNIFICADOS YA MENCIONADOS, CON DERIVADOS DE ACIDOS DE FORMULA GENERAL(III), EN LA QUE R TIENE EL SIGNIFICADO YA MENCIONADO; Y Z SIGNIFICA UN GRUPO NUCLEOFUGO, EN UN DISOLVENTE INERTE.DE APLICACION COMO INHIBIDORES DE ULCERAS Y DE SECRECIONES.
ES519529A 1982-02-06 1983-02-04 Procedimiento para la preparacion de nuevas tienobenzodiazepinonas sustituidas. Expired ES8403129A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823204153 DE3204153A1 (de) 1982-02-06 1982-02-06 Substituierte thienobenzodiazepinone, verfahren zu ihrer herstellung und sie enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES519529A0 ES519529A0 (es) 1984-03-01
ES8403129A1 true ES8403129A1 (es) 1984-03-01

Family

ID=6155010

Family Applications (2)

Application Number Title Priority Date Filing Date
ES519529A Expired ES8403129A1 (es) 1982-02-06 1983-02-04 Procedimiento para la preparacion de nuevas tienobenzodiazepinonas sustituidas.
ES526538A Expired ES8407052A1 (es) 1982-02-06 1983-10-18 Procedimiento para la preparacion de nuevas tienobenzodiazepinonas sustituidas

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES526538A Expired ES8407052A1 (es) 1982-02-06 1983-10-18 Procedimiento para la preparacion de nuevas tienobenzodiazepinonas sustituidas

Country Status (7)

Country Link
US (1) US4424225A (es)
EP (1) EP0086982A1 (es)
JP (1) JPS58146584A (es)
AU (1) AU1112183A (es)
DE (1) DE3204153A1 (es)
ES (2) ES8403129A1 (es)
ZA (1) ZA83772B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3409237A1 (de) * 1984-03-14 1985-09-19 Dr. Karl Thomae Gmbh, 7950 Biberach Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CH667657A5 (de) * 1985-01-07 1988-10-31 Sandoz Ag Carbocyclische und heterocyclische carbonylmethylen- und methylpiperidine und -pyrrolidine.
DE3529372A1 (de) * 1985-08-16 1987-02-19 Dompe Farmaceutici Spa Aminoacyl-derivat von 4,9-dihydro-10h-pyrido(3,2-b)-thieno(3,2-e) (1,4)-diazepinon und von 4,9-dihydro-10h-pyrido(3,2-b)thieno(3,4-e) (1,4)diazepinon, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen
DE3726908A1 (de) * 1987-08-13 1989-02-23 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3930262A1 (de) * 1989-09-11 1991-03-21 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3930266A1 (de) * 1989-09-11 1991-03-14 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5324832A (en) * 1991-07-03 1994-06-28 The United States Of America As Represented By The Department Of Health And Human Services Muscarinic antagonists
CA2935944A1 (en) 2014-01-09 2015-07-16 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Substituted benzoxazine and related compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795176C3 (de) * 1968-08-20 1974-10-24 Dr. Karl Thomae Gmbh, 7950 Biberach hT-substituierte 5-Aminoacetyl-5,10-dihydro-l lH-dibenzo eckige Klammer auf b,e eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu diazepin-11one und Verfahren zu ihrer Herstellung
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
US4381301A (en) 1980-05-07 1983-04-26 Byk Gulden Lomberg Chemische Fabrik Gmbh Substituted tricyclic thieno compounds, their synthesis, their use, their compositions and their medicaments

Also Published As

Publication number Publication date
US4424225A (en) 1984-01-03
DE3204153A1 (de) 1983-08-11
JPS58146584A (ja) 1983-09-01
ES519529A0 (es) 1984-03-01
ES526538A0 (es) 1984-08-16
ZA83772B (en) 1984-10-31
EP0086982A1 (de) 1983-08-31
AU1112183A (en) 1983-08-11
ES8407052A1 (es) 1984-08-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010402