ES8406456A1 - Procedimiento de preparacion de derivados de piperacina - Google Patents

Procedimiento de preparacion de derivados de piperacina

Info

Publication number
ES8406456A1
ES8406456A1 ES522650A ES522650A ES8406456A1 ES 8406456 A1 ES8406456 A1 ES 8406456A1 ES 522650 A ES522650 A ES 522650A ES 522650 A ES522650 A ES 522650A ES 8406456 A1 ES8406456 A1 ES 8406456A1
Authority
ES
Spain
Prior art keywords
denotes
group
lower alkyl
alkyl group
piperazine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES522650A
Other languages
English (en)
Other versions
ES522650A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fordonal SA
Original Assignee
Fordonal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838304528A external-priority patent/GB8304528D0/en
Application filed by Fordonal SA filed Critical Fordonal SA
Publication of ES522650A0 publication Critical patent/ES522650A0/es
Publication of ES8406456A1 publication Critical patent/ES8406456A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE PIPERACINA, DE FORMULA GENERAL (I).CONSISTE EN HACER REACCIONAR UN HALURO DE FORMULA GENERAL (II) CON UNA PIPERACINA MONOSUSTITUIDA DE FORMULA GENERAL (III), EN UN DISOLVENTE ORGANICO INERTE, PREFERENTEMENTE TOLUENO, XILENO, DIOXANO O METIL ISOBUTIL CETONA.DE APLICACION EN EL TRATAMIENTO DE LA ANGINA, EN LA INSUFICIENCIA VASCULAR PERIFERICA O CEREBRAL Y EN EL VERTIGO.
ES522650A 1982-05-25 1983-05-24 Procedimiento de preparacion de derivados de piperacina Expired ES8406456A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8215219 1982-05-25
GB838304528A GB8304528D0 (en) 1983-02-18 1983-02-18 Piperazine derivatives

Publications (2)

Publication Number Publication Date
ES522650A0 ES522650A0 (es) 1984-08-01
ES8406456A1 true ES8406456A1 (es) 1984-08-01

Family

ID=26282941

Family Applications (6)

Application Number Title Priority Date Filing Date
ES522653A Granted ES522653A0 (es) 1982-05-25 1983-05-24 Procedimiento de preparacion de derivados de piperacina.
ES522651A Granted ES522651A0 (es) 1982-05-25 1983-05-24 Procedimiento de preparacion de derivados de piperacina
ES522650A Expired ES8406456A1 (es) 1982-05-25 1983-05-24 Procedimiento de preparacion de derivados de piperacina
ES522652A Expired ES8502981A1 (es) 1982-05-25 1983-05-24 Procedimiento de preparacion de derivados de piperacina.
ES535909A Expired ES8600636A1 (es) 1982-05-25 1984-09-14 Procedimiento de preparacion de derivados de piperacina
ES535910A Expired ES8600637A1 (es) 1982-05-25 1984-09-14 Procedimiento de preparacion de derivados de piperacina

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES522653A Granted ES522653A0 (es) 1982-05-25 1983-05-24 Procedimiento de preparacion de derivados de piperacina.
ES522651A Granted ES522651A0 (es) 1982-05-25 1983-05-24 Procedimiento de preparacion de derivados de piperacina

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES522652A Expired ES8502981A1 (es) 1982-05-25 1983-05-24 Procedimiento de preparacion de derivados de piperacina.
ES535909A Expired ES8600636A1 (es) 1982-05-25 1984-09-14 Procedimiento de preparacion de derivados de piperacina
ES535910A Expired ES8600637A1 (es) 1982-05-25 1984-09-14 Procedimiento de preparacion de derivados de piperacina

Country Status (4)

Country Link
DE (1) DE3318577A1 (es)
ES (6) ES522653A0 (es)
FR (1) FR2527605A1 (es)
IT (1) IT1169416B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8506679A2 (es) * 1984-01-17 1985-08-01 Ferrer Int Mejoras en el objeto de la patente de invencion n 514.340 que se refiere a: procedimiento de obtencion de nuevos derivados de piperazina
US7071197B2 (en) 2002-06-14 2006-07-04 Recordati S.A. N,N-disubstituted diazocycloalkanes
ITMI20021327A1 (it) * 2002-06-14 2003-12-15 Recordati Chem Pharm Nuove ossialchilpiperazine
CN1326845C (zh) * 2003-11-05 2007-07-18 河北医科大学 双苯氟嗪的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2997474A (en) * 1959-10-12 1961-08-22 Paul A J Janssen 1-aryl-omega-(4-arylpiperazine) alkanols
FR1485246A (fr) * 1966-06-30 1967-06-16 Science Union & Cie Nouveaux dérivés de la piperonyl-piperazine et leur procédé de préparation
BE758380A (fr) * 1969-11-04 1971-04-16 Sumitomo Chemical Co Procede de preparation de derives d'aryl-cetones
FR2081579B1 (es) * 1970-03-18 1973-04-06 Delalande Sa

Also Published As

Publication number Publication date
ES522650A0 (es) 1984-08-01
ES535909A0 (es) 1985-10-16
IT8321230A0 (it) 1983-05-23
ES8406457A1 (es) 1984-08-01
FR2527605A1 (fr) 1983-12-02
ES8407318A1 (es) 1984-09-16
ES522652A0 (es) 1985-02-01
ES535910A0 (es) 1985-10-16
ES8600636A1 (es) 1985-10-16
ES8502981A1 (es) 1985-02-01
ES522651A0 (es) 1984-08-01
ES522653A0 (es) 1984-09-16
ES8600637A1 (es) 1985-10-16
DE3318577A1 (de) 1983-12-01
IT1169416B (it) 1987-05-27

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