ES8701717A1 - Un procedimiento para la preparacion de nuevos derivados del acido (5-amino-2-hidroxi)benzoico. - Google Patents
Un procedimiento para la preparacion de nuevos derivados del acido (5-amino-2-hidroxi)benzoico.Info
- Publication number
- ES8701717A1 ES8701717A1 ES549359A ES549359A ES8701717A1 ES 8701717 A1 ES8701717 A1 ES 8701717A1 ES 549359 A ES549359 A ES 549359A ES 549359 A ES549359 A ES 549359A ES 8701717 A1 ES8701717 A1 ES 8701717A1
- Authority
- ES
- Spain
- Prior art keywords
- amino
- pharmaceutical compositions
- acid derivatives
- salicylic acid
- imidazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
UN PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS DERIVADOS DEL ACIDO (5-AMINO-2-HIDROXI) BENZOICO DE FORMULA (I). SE HACE REACCIONAR ACIDO 2-HIDROXI-5-AMINOBENZOICO CON CLORUROS DE ACILO O ANHIDRIDOS DE ACIDOS DE FORMULA RCOOH, Y LOS DERIVADOS N,O-DIACILICOS OBTENIDOS SE HIDROLIZAN EN PRESENCIA DE IMIDAZOL Y, POSTERIORMENTE, SE HACEN REACCIONAR CON LA BASE B. ESTOS COMPUESTOS SON APLICABLES COMO ANTIINFLAMATORIOS, ANTIAGREGATORIOS Y ANTITROMBOTICOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT23799/84A IT1196348B (it) | 1984-11-29 | 1984-11-29 | Composti ad attivita'antiinfiammatoria |
Publications (2)
Publication Number | Publication Date |
---|---|
ES549359A0 ES549359A0 (es) | 1986-12-01 |
ES8701717A1 true ES8701717A1 (es) | 1986-12-01 |
Family
ID=11210091
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES549359A Expired ES8701717A1 (es) | 1984-11-29 | 1985-11-28 | Un procedimiento para la preparacion de nuevos derivados del acido (5-amino-2-hidroxi)benzoico. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0236329A1 (es) |
JP (1) | JPS62501703A (es) |
KR (1) | KR870700608A (es) |
CN (1) | CN85109554A (es) |
AU (1) | AU5231186A (es) |
DK (1) | DK346486A (es) |
ES (1) | ES8701717A1 (es) |
GR (1) | GR852834B (es) |
IT (1) | IT1196348B (es) |
PT (1) | PT81566B (es) |
WO (1) | WO1986003199A1 (es) |
ZA (1) | ZA859035B (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9017711D0 (en) * | 1990-08-13 | 1990-09-26 | May & Baker Ltd | New compositions of matter |
GB9017710D0 (en) * | 1990-08-13 | 1990-09-26 | May & Baker Ltd | New compositions of matter |
IT1244873B (it) * | 1990-09-12 | 1994-09-12 | Depha Team Srl | Derivati dell'acido 5-aminosalicilico (5-asa) per la terapia delle infiammazioni croniche intestinali |
US5366987A (en) * | 1991-08-22 | 1994-11-22 | Warner-Lambert Company | Isoxazolyl-substituted alkyl amide ACAT inhibitors |
FR2738150B1 (fr) * | 1995-09-01 | 1997-10-31 | Synthelabo | Utilisation de la sulphasalazine et de ses metabolites pour la fabrication d'un medicament utile dans le traitement de l'insuffisance veineuse et des ulceres veineux |
CN1939895B (zh) * | 2000-04-19 | 2010-05-12 | 纽若泰克有限公司 | 预防中枢神经系统急慢性损伤中神经变性的化合物,组合物和方法 |
US6573402B1 (en) | 2000-04-20 | 2003-06-03 | Neurotech Co., Ltd. | Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system |
DE60114724T2 (de) * | 2000-07-18 | 2006-06-01 | Dainichiseika Color & Chemicals Mfg. Co., Ltd. | Blutflussverbesserer und Mittel zur Vorbeugung oder Heilung von Thrombose |
ATE462969T1 (de) | 2001-01-19 | 2010-04-15 | Apex Biotechnology Corp | Nicht enzymatischer einwegerkennungselektrodenstreifen der einen oberflächenaktiven stoff beinhaltet, zum nachweis von harnsäure; herstellungsverfahren dafür und verwendung davon |
EP1429765A2 (en) | 2001-09-14 | 2004-06-23 | Methylgene, Inc. | Inhibitors of histone deacetylase |
CA2490120C (en) | 2002-06-19 | 2010-06-01 | Neurotech Co., Ltd. | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same |
KR100668111B1 (ko) | 2005-07-28 | 2007-01-12 | (주)에스에이치제약 | 강력한 항산화 효과를 가짐으로써 급성 및 퇴행성 뇌신경계질환의 예방 및 치료에 이용 가능한 신규물질인아미노살리실산 유도체와 그 염의 제조방법 |
KR101335029B1 (ko) * | 2006-04-13 | 2013-11-28 | 주식회사 지엔티파마 | 세포 손상 및 염증 질환의 치료 또는 예방용 약학 조성물 |
CN100422721C (zh) * | 2006-05-26 | 2008-10-01 | 南京大学 | 一种利用糖基萘酚的铝离子检测方法 |
CN102872020A (zh) * | 2007-10-23 | 2013-01-16 | 株式会社医药分子设计研究所 | Pai-1产生抑制剂 |
KR100852962B1 (ko) | 2007-11-12 | 2008-08-20 | 주식회사 뉴로테크 | 2-하이드록시-5-페닐알킬아미노벤조산 유도체 및 이의 염의제조방법 |
LT2315740T (lt) | 2008-07-08 | 2018-02-26 | Catabasis Pharmaceuticals, Inc. | Acetilinti riebalų rūgščių salicilatai ir jų panaudojimas |
US9085527B2 (en) | 2008-07-08 | 2015-07-21 | Catabasis Pharmaceuticals, Inc. | Fatty acid acylated salicylates and their uses |
KR101204108B1 (ko) * | 2009-02-09 | 2012-11-22 | 주식회사 지엔티파마 | 5-벤질아미노살리실산 유도체 또는 이의 염의 의약 용도 |
CN102724877B (zh) | 2009-09-01 | 2015-05-13 | 凯特贝希制药公司 | 脂肪酸烟酸缀合物及其用途 |
USRE46608E1 (en) | 2009-09-01 | 2017-11-14 | Catabasis Pharmaceuticals, Inc. | Fatty acid niacin conjugates and their uses |
CA2873096A1 (en) * | 2012-05-23 | 2013-11-28 | Cellixbio Private Limited | Compositions and methods for the treatment of inflammatory bowel disease |
WO2014070859A1 (en) | 2012-10-30 | 2014-05-08 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Stat3 dimerization inhibitors |
CA3124767A1 (en) * | 2018-12-28 | 2020-07-02 | Gnt Pharma Co., Ltd. | 5-benzylaminosalicylic acid compounds for treating neurodegenerative disorders |
CN111116395B (zh) * | 2019-12-27 | 2023-04-07 | 湖北工业大学 | 多碘代芳香酸类化合物及其在抗腺病毒7型中的应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR4546M (es) * | 1964-06-09 | 1966-11-02 | ||
NL7008623A (es) * | 1969-06-25 | 1970-12-29 | ||
JPS5640710B2 (es) * | 1973-01-18 | 1981-09-22 | ||
JPS6056130B2 (ja) * | 1978-03-20 | 1985-12-09 | 久光製薬株式会社 | 新規なサリチル酸誘導体 |
US4536346A (en) * | 1983-05-06 | 1985-08-20 | American Cyanamid Company | Aralkanamidophenyl compounds |
-
1984
- 1984-11-29 IT IT23799/84A patent/IT1196348B/it active
-
1985
- 1985-11-25 GR GR852834A patent/GR852834B/el unknown
- 1985-11-26 EP EP86900097A patent/EP0236329A1/en not_active Withdrawn
- 1985-11-26 ZA ZA859035A patent/ZA859035B/xx unknown
- 1985-11-26 AU AU52311/86A patent/AU5231186A/en not_active Abandoned
- 1985-11-26 WO PCT/EP1985/000645 patent/WO1986003199A1/en not_active Application Discontinuation
- 1985-11-26 JP JP61500163A patent/JPS62501703A/ja active Pending
- 1985-11-27 CN CN198585109554A patent/CN85109554A/zh active Pending
- 1985-11-27 PT PT81566A patent/PT81566B/pt unknown
- 1985-11-28 ES ES549359A patent/ES8701717A1/es not_active Expired
-
1986
- 1986-07-21 DK DK346486A patent/DK346486A/da not_active Application Discontinuation
- 1986-07-28 KR KR1019860700507A patent/KR870700608A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DK346486D0 (da) | 1986-07-21 |
DK346486A (da) | 1986-07-21 |
GR852834B (es) | 1986-03-27 |
PT81566A (en) | 1985-12-01 |
ES549359A0 (es) | 1986-12-01 |
IT8423799A0 (it) | 1984-11-29 |
EP0236329A1 (en) | 1987-09-16 |
PT81566B (en) | 1987-04-07 |
WO1986003199A1 (en) | 1986-06-05 |
KR870700608A (ko) | 1987-12-30 |
ZA859035B (en) | 1986-08-27 |
IT1196348B (it) | 1988-11-16 |
CN85109554A (zh) | 1986-07-23 |
JPS62501703A (ja) | 1987-07-09 |
AU5231186A (en) | 1986-06-18 |
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