ES8701683A1 - Un procedimiento para la preparacion de una composicion terapeutica que contiene un fosfato de dialquilo. - Google Patents
Un procedimiento para la preparacion de una composicion terapeutica que contiene un fosfato de dialquilo.Info
- Publication number
- ES8701683A1 ES8701683A1 ES547738A ES547738A ES8701683A1 ES 8701683 A1 ES8701683 A1 ES 8701683A1 ES 547738 A ES547738 A ES 547738A ES 547738 A ES547738 A ES 547738A ES 8701683 A1 ES8701683 A1 ES 8701683A1
- Authority
- ES
- Spain
- Prior art keywords
- independently represent
- external application
- medical composition
- carbon atoms
- hydrocarbon group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910019142 PO4 Inorganic materials 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 2
- 239000010452 phosphate Substances 0.000 abstract 2
- 230000001780 adrenocortical effect Effects 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- BLFLLBZGZJTVJG-UHFFFAOYSA-N benzocaine Chemical compound CCOC(=O)C1=CC=C(N)C=C1 BLFLLBZGZJTVJG-UHFFFAOYSA-N 0.000 abstract 1
- 229960005274 benzocaine Drugs 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229960000890 hydrocortisone Drugs 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
METODO DE PREPARACION DE COMPOSICIONES QUED CONTIENEN UN FOSFATO DE DIALQUILO. COMPRENDE LA PREPARACION DE UNA SUSPENSION ACUOSA O EN AGUA-ETANOL QUE CONTIENE UN INGREDIENTE TERAPEUTICO Y UN FOSFATO DE DIALQUILO, DE FORMULA (I), EN LA QUE R1 Y R2 REPRESENTAN UN RADICAL HIDROCARBONADO C6-24, R3 Y R4 REPRESENTAN UN RADICAL HIDROCARBONADO C2-6, M Y N VALEN DE 0-20, Y X PUEDE SER VARIOS TIPOS DE RADICALES. LA MEZCLA SE AGITA MEDIANTE IRRADIACION CON ONDAS ULTRASONICAS, A UNA TEMPERATURA COMPRENDIDA ENTRE 3JC Y 100JC. ESTAS COMPOSICIONES TIENEN APLICACIONES FARMACOLOGICAS DIVERSAS DEPENDIENDO DEL INGREDIENTE TERAPEUTICO QUE CONTIENEN.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59213152A JPS6191137A (ja) | 1984-10-11 | 1984-10-11 | 外用薬剤組成物 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8701683A1 true ES8701683A1 (es) | 1986-12-01 |
ES547738A0 ES547738A0 (es) | 1986-12-01 |
Family
ID=16634426
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES547738A Expired ES8701683A1 (es) | 1984-10-11 | 1985-10-09 | Un procedimiento para la preparacion de una composicion terapeutica que contiene un fosfato de dialquilo. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4686211A (es) |
EP (1) | EP0179277B1 (es) |
JP (1) | JPS6191137A (es) |
DE (1) | DE3565937D1 (es) |
ES (1) | ES8701683A1 (es) |
HK (1) | HK33691A (es) |
MY (1) | MY100022A (es) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01151516A (ja) * | 1987-12-08 | 1989-06-14 | Shionogi & Co Ltd | ビタミンe配合外用剤 |
GB8828017D0 (en) * | 1988-12-01 | 1989-01-05 | Unilever Plc | Topical composition |
GB8828014D0 (en) * | 1988-12-01 | 1989-01-05 | Unilever Plc | Topical composition |
GB8828018D0 (en) * | 1988-12-01 | 1989-01-05 | Unilever Plc | Topical composition |
GB8828020D0 (en) * | 1988-12-01 | 1989-01-05 | Unilever Plc | Topical composition |
GB8828013D0 (en) * | 1988-12-01 | 1989-01-05 | Unilever Plc | Topical composition |
US4906454A (en) * | 1989-02-23 | 1990-03-06 | The Procter & Gamble Company | Deodorant compositions containing specific piroctone salts and perfumes |
US5262165A (en) * | 1992-02-04 | 1993-11-16 | Schering Corporation | Transdermal nitroglycerin patch with penetration enhancers |
GB9003199D0 (en) * | 1990-02-13 | 1990-04-11 | Unilever Plc | Topical composition |
US5565207A (en) * | 1990-09-19 | 1996-10-15 | Pola Kasei Kogyo Kabushiki Kaisha | Scalp moisturizer and external skin preparation |
GB9101986D0 (en) * | 1991-01-30 | 1991-03-13 | Smith & Nephew | Pharmaceutical compositions |
US5409911A (en) * | 1992-09-11 | 1995-04-25 | Merck & Co., Inc. | Prostaglandin analog for treating osteoporosis |
TW251302B (es) * | 1992-12-28 | 1995-07-11 | Kao Corp | |
US5665742A (en) * | 1994-05-31 | 1997-09-09 | Kao Corporation | Bath medicine composition and its use in inhibiting the generation of body odor |
US5543430A (en) * | 1994-10-05 | 1996-08-06 | Kaesemeyer; W. H. | Method and formulation of stimulating nitric oxide synthesis |
US20110196039A9 (en) * | 1994-10-05 | 2011-08-11 | Kaesemeyer Wayne H | Controlled release arginine formulations |
US6239172B1 (en) * | 1997-04-10 | 2001-05-29 | Nitrosystems, Inc. | Formulations for treating disease and methods of using same |
US5968983A (en) * | 1994-10-05 | 1999-10-19 | Nitrosystems, Inc | Method and formulation for treating vascular disease |
US5560913A (en) * | 1995-01-27 | 1996-10-01 | The Procter & Gamble Company | Pharmaceutical compositions |
US6605751B1 (en) * | 1997-11-14 | 2003-08-12 | Acrymed | Silver-containing compositions, devices and methods for making |
WO1999039575A2 (en) * | 1998-02-09 | 1999-08-12 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Synergistic biocidal activity of ternary complexes of negatively -charged biocides (component a), transition metal ions (component b), and neutral chelators (component c) |
US5972920A (en) * | 1998-02-12 | 1999-10-26 | Dermalogix Partners, Inc. | Formulation containing a carrier, active ingredient, and surfactant for treating skin disorders |
US6121253A (en) * | 1998-11-20 | 2000-09-19 | Merck Frosst Canada & Co. | Prostaglandin conjugates for treating or preventing bone disease |
US6254294B1 (en) * | 1999-08-09 | 2001-07-03 | Sigrid G. Muhar | Pharmaceutical kit |
FR2799369B1 (fr) * | 1999-10-08 | 2001-12-21 | Oreal | Association d'escine et de sulfate de dextran et son utilisation |
DE60028415T2 (de) * | 1999-12-30 | 2007-06-06 | Acrymed, Portland | Methode und zusammensetzungen für verbesserte abgabevorrichtungen |
US7758888B2 (en) * | 2000-04-21 | 2010-07-20 | Sol-Gel Technologies Ltd. | Composition exhibiting enhanced formulation stability and delivery of topical active ingredients |
AUPR549901A0 (en) | 2001-06-06 | 2001-07-12 | Vital Health Sciences Pty Ltd | Topical formulation containing tocopheryl phosphates |
CA2426885C (en) * | 2000-11-14 | 2010-06-29 | Vital Health Sciences Pty Ltd | Complexes of phosphate derivatives |
EP1254909A1 (de) * | 2001-04-30 | 2002-11-06 | Cognis Iberia, S.L. | Phosphorsäureester |
CN1547475B (zh) * | 2001-07-27 | 2010-12-15 | 生命健康科学有限公司 | 含电子转移试剂的磷酸酯衍生物的皮肤制剂 |
EP1460995B1 (en) * | 2001-12-13 | 2010-11-10 | Vital Health Sciences Pty Ltd. | Transdermal transport of compounds |
US6833139B1 (en) * | 2002-01-09 | 2004-12-21 | Ferndale Laboratories, Inc. | Composition and method for the treatment of anorectal disorders |
US8486426B2 (en) * | 2002-07-29 | 2013-07-16 | Kimberly-Clark Worldwide, Inc. | Methods and compositions for treatment of dermal conditions |
AU2002950713A0 (en) * | 2002-08-09 | 2002-09-12 | Vital Health Sciences Pty Ltd | Carrier |
ATE534384T1 (de) * | 2003-01-17 | 2011-12-15 | Vital Health Sciences Pty Ltd | Verbindungen mit proliferationshemmenden eigenschaften |
AU2003901815A0 (en) * | 2003-04-15 | 2003-05-01 | Vital Health Sciences Pty Ltd | Phosphate derivatives |
US20060281716A1 (en) | 2004-03-03 | 2006-12-14 | West Simon M | Alkaloid formulations |
US20050282870A1 (en) * | 2004-06-16 | 2005-12-22 | Carter Stephen G | Peripherally-acting vasodilators |
CN101010004B (zh) * | 2004-07-30 | 2012-10-03 | 金伯利-克拉克环球有限公司 | 抗微生物的装置和组合物 |
US8361553B2 (en) | 2004-07-30 | 2013-01-29 | Kimberly-Clark Worldwide, Inc. | Methods and compositions for metal nanoparticle treated surfaces |
AU2005280443B2 (en) | 2004-07-30 | 2011-02-03 | Avent, Inc. | Antimicrobial silver compositions |
WO2006034249A2 (en) * | 2004-09-20 | 2006-03-30 | Acrymed, Inc. | Antimicrobial amorphous compositions |
JP2008531602A (ja) * | 2005-03-03 | 2008-08-14 | バイタル ヘルス サイエンシズ プロプライアタリー リミティド | 抗癌特性を有する化合物 |
NZ565049A (en) * | 2005-06-17 | 2012-02-24 | Vital Health Sciences Pty Ltd | A carrier comprising one or more DI and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof |
EP2431088A1 (en) * | 2005-08-02 | 2012-03-21 | Sol-Gel Technologies Ltd. | Metal oxide coating of water insoluble ingredients |
CA2631653A1 (en) * | 2005-12-23 | 2007-06-28 | Vital Health Sciences Pty Ltd. | Compounds having cytokine modulating properties |
EP2015722B1 (en) * | 2006-04-28 | 2016-11-16 | Avent, Inc. | Antimicrobial site dressings |
CA2677184C (en) | 2007-02-01 | 2014-12-23 | Sol-Gel Technologies Ltd. | Compositions for topical application comprising a peroxide and retinoid |
US20100016443A1 (en) * | 2007-02-01 | 2010-01-21 | Sol-Gel Technologies Ltd. | Method for preparing particles comprising metal oxide coating and particles with metal oxide coating |
AU2009316270B2 (en) * | 2008-11-24 | 2015-08-27 | Avent, Inc. | Antimicrobial laminate constructs |
JP2010235523A (ja) * | 2009-03-31 | 2010-10-21 | Kao Corp | 水性毛髪洗浄剤 |
US10071030B2 (en) | 2010-02-05 | 2018-09-11 | Phosphagenics Limited | Carrier comprising non-neutralised tocopheryl phosphate |
CA2794734C (en) | 2010-03-30 | 2017-12-12 | Phosphagenics Limited | Transdermal delivery patch |
EP2685992A4 (en) | 2011-03-15 | 2014-09-10 | Phosphagenics Ltd | AMINO-QUINOLINES AS KINASE INHIBITORS |
US9687465B2 (en) | 2012-11-27 | 2017-06-27 | Sol-Gel Technologies Ltd. | Compositions for the treatment of rosacea |
CN114712308A (zh) | 2015-12-09 | 2022-07-08 | 磷肌酸有限公司 | 药物制剂 |
AU2017381395A1 (en) | 2016-12-21 | 2019-06-20 | Phosphagenics Limited | Process |
JP2019043853A (ja) * | 2017-08-30 | 2019-03-22 | 旭化成株式会社 | 経皮吸収促進剤、経皮吸収促進助剤、及び経皮製剤 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4046886A (en) * | 1975-01-17 | 1977-09-06 | The Procter & Gamble Company | Dermatological compositions |
US4130667A (en) * | 1976-01-12 | 1978-12-19 | The Procter & Gamble Company | Dermatological compositions |
-
1984
- 1984-10-11 JP JP59213152A patent/JPS6191137A/ja active Granted
-
1985
- 1985-09-19 EP EP85111872A patent/EP0179277B1/en not_active Expired
- 1985-09-19 DE DE8585111872T patent/DE3565937D1/de not_active Expired
- 1985-09-20 US US06/778,226 patent/US4686211A/en not_active Expired - Fee Related
- 1985-10-09 ES ES547738A patent/ES8701683A1/es not_active Expired
-
1987
- 1987-03-26 MY MYPI87000383A patent/MY100022A/en unknown
-
1991
- 1991-05-02 HK HK336/91A patent/HK33691A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US4686211A (en) | 1987-08-11 |
EP0179277B1 (en) | 1988-11-02 |
MY100022A (en) | 1989-04-20 |
EP0179277A1 (en) | 1986-04-30 |
DE3565937D1 (en) | 1988-12-08 |
JPS6191137A (ja) | 1986-05-09 |
ES547738A0 (es) | 1986-12-01 |
JPH0469129B2 (es) | 1992-11-05 |
HK33691A (en) | 1991-05-10 |
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