ES8609244A1 - Un procedimiento para la preparacion de un compuesto de 1,3 -diacil-2-oxindol - Google Patents

Un procedimiento para la preparacion de un compuesto de 1,3 -diacil-2-oxindol

Info

Publication number
ES8609244A1
ES8609244A1 ES547054A ES547054A ES8609244A1 ES 8609244 A1 ES8609244 A1 ES 8609244A1 ES 547054 A ES547054 A ES 547054A ES 547054 A ES547054 A ES 547054A ES 8609244 A1 ES8609244 A1 ES 8609244A1
Authority
ES
Spain
Prior art keywords
alkyl
phenyl
thiadiazole
cycloalkyl
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES547054A
Other languages
English (en)
Other versions
ES547054A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES547054A0 publication Critical patent/ES547054A0/es
Publication of ES8609244A1 publication Critical patent/ES8609244A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

METODO DE OBTENCION DE 1,3-DIACIL-2-OXINDOL. CONSISTENTE EN SOMETER A ACILACION UN COMPUESTO DE FORMULA (I) DONDE <A> ES H Y <B> ES -CO-R1, O BIEN <A> ES -CO-R2 Y <B> ES H, Y EN LOS QUE R1 REPRESENTA UN RADICAL ALQUILICO CON O SIN SUSTITUYENTES AROMATICOS Y R2 ES ALQUILO DE 1 A 5 ATOMOS DE C; X REPRESENTA H, F, CL, BR O TRIFLUOROMETILO E Y ES H; CON UN DERIVADO ACTIVO DE ACIDO CARBOXILICO DE FORMULA RK-C(FO)-OF EN DONDE RK ES R1 SI <B> ES H Y RK ES R2 SI <A> ES H, EN UNA CANTIDAD DE UN EQUIVALENTE MOLAR. LA REACCION TIENE LUGAR EN DISOLVENTE APROTICO POLAR (N,N-DIMETILFORMAMIDA,N,N-DIMETILACETAMIDA,N-METILPIRROLIDONA O DIMETILSULFOXIDO), EN PRESENCIA DE UNA AMINA TERCIARIA EN UNA CANTIDAD DE 1 A 4 EQUIVALENTES Y A UNA TEMPERARTURA COMPRENDIDA ENTRE C20J A 25JC. DE APLICACION TERAPEUTICA POR SU ACCION ANALGESICA Y ANTIINFLAMATORIA.
ES547054A 1984-09-19 1985-09-17 Un procedimiento para la preparacion de un compuesto de 1,3 -diacil-2-oxindol Expired ES8609244A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65237284A 1984-09-19 1984-09-19

Publications (2)

Publication Number Publication Date
ES547054A0 ES547054A0 (es) 1986-07-16
ES8609244A1 true ES8609244A1 (es) 1986-07-16

Family

ID=24616591

Family Applications (1)

Application Number Title Priority Date Filing Date
ES547054A Expired ES8609244A1 (es) 1984-09-19 1985-09-17 Un procedimiento para la preparacion de un compuesto de 1,3 -diacil-2-oxindol

Country Status (7)

Country Link
JP (1) JPS6178765A (es)
KR (1) KR870000289B1 (es)
ES (1) ES8609244A1 (es)
FI (1) FI80270C (es)
HU (1) HU194165B (es)
PL (1) PL145950B1 (es)
PT (1) PT81140B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives
DE19808261A1 (de) * 1998-02-27 1999-10-28 Bayer Ag Arylphenylsubstituierte cyclische Ketoenole
EP2569283B1 (de) * 2010-05-10 2014-08-27 Bayer Intellectual Property GmbH Verfahren zur herstellung von substituierten 1,3-dihydro-2h-indol-2-onen
WO2014061752A1 (ja) * 2012-10-17 2014-04-24 国立大学法人岡山大学 化合物、その互変異性体、幾何異性体、乃至それらの塩、及びそれらの製造方法、抗菌剤、並びに感染症治療薬

Also Published As

Publication number Publication date
PT81140A (en) 1985-10-01
FI853163L (fi) 1986-03-20
PL255399A1 (en) 1986-08-12
FI80270B (fi) 1990-01-31
FI853163A0 (fi) 1985-08-16
ES547054A0 (es) 1986-07-16
JPH049781B2 (es) 1992-02-21
HUT38906A (en) 1986-07-28
HU194165B (en) 1988-01-28
PT81140B (pt) 1988-01-22
KR860002505A (ko) 1986-04-26
KR870000289B1 (ko) 1987-02-25
JPS6178765A (ja) 1986-04-22
PL145950B1 (en) 1988-12-31
FI80270C (fi) 1990-05-10

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20040424