ES8607985A1 - Procedimiento de preparacion de 20-ceto-delta 16-esteroides y nuevos compuestos intermedios formados en este procedimiento - Google Patents
Procedimiento de preparacion de 20-ceto-delta 16-esteroides y nuevos compuestos intermedios formados en este procedimientoInfo
- Publication number
- ES8607985A1 ES8607985A1 ES532030A ES532030A ES8607985A1 ES 8607985 A1 ES8607985 A1 ES 8607985A1 ES 532030 A ES532030 A ES 532030A ES 532030 A ES532030 A ES 532030A ES 8607985 A1 ES8607985 A1 ES 8607985A1
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- steroids
- ceto
- delta
- intermediate compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical group [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 abstract 1
- -1 PROGESTERONE STEROIDS Chemical class 0.000 abstract 1
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Natural products C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 239000000908 ammonium hydroxide Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000003983 crown ethers Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 229910000000 metal hydroxide Inorganic materials 0.000 abstract 1
- 150000004692 metal hydroxides Chemical class 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000003444 phase transfer catalyst Substances 0.000 abstract 1
- 229960003387 progesterone Drugs 0.000 abstract 1
- 239000000186 progesterone Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP83200617A EP0123735A1 (en) | 1983-04-29 | 1983-04-29 | New process for the preparation of 20-keto-delta-16-steroids and new intermediate compounds formed in this process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8607985A1 true ES8607985A1 (es) | 1986-06-01 |
| ES532030A0 ES532030A0 (es) | 1986-06-01 |
Family
ID=8190950
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES532030A Expired ES8607985A1 (es) | 1983-04-29 | 1984-04-28 | Procedimiento de preparacion de 20-ceto-delta 16-esteroides y nuevos compuestos intermedios formados en este procedimiento |
| ES551558A Expired ES8801837A1 (es) | 1983-04-29 | 1986-02-01 | Procedimiento de preparacion de 20-ceto-delta16-esteroides |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES551558A Expired ES8801837A1 (es) | 1983-04-29 | 1986-02-01 | Procedimiento de preparacion de 20-ceto-delta16-esteroides |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4551278A (https=) |
| EP (2) | EP0123735A1 (https=) |
| JP (2) | JPS59206398A (https=) |
| KR (1) | KR860001496B1 (https=) |
| AU (1) | AU567734B2 (https=) |
| CA (1) | CA1291747C (https=) |
| DE (1) | DE3474965D1 (https=) |
| DK (2) | DK166026C (https=) |
| ES (2) | ES8607985A1 (https=) |
| FI (1) | FI82060C (https=) |
| GR (1) | GR81988B (https=) |
| HU (2) | HU194907B (https=) |
| IE (1) | IE57252B1 (https=) |
| IL (1) | IL71660A (https=) |
| NO (1) | NO167513C (https=) |
| NZ (1) | NZ207987A (https=) |
| PT (1) | PT78505B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2677029B1 (fr) * | 1991-05-23 | 1994-01-21 | Roussel Uclaf | Nouveaux derives sterouides de l'andostra-4,9(11),16-trien-3-one. |
| FR2677028B1 (fr) * | 1991-05-23 | 1994-01-21 | Roussel Uclaf | Nouveaux derives sterouides du pregna-4,9(11),17(20)-trien-3-one. |
| FR2676740B1 (fr) * | 1991-05-23 | 1993-11-05 | Roussel Uclaf | Nouveaux derives sterouides du pregna-4,9(11),17(20)-trie-3-one, leur preparation, leur application a la preparation de composes sterouides de type pregna-4,9(11),16-triene-3,20-dione et nouveaux intermediaires. |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2420489A (en) * | 1941-05-15 | 1947-05-13 | Parke Davis & Co | Steroidal hormone intermediates and preparation of the same |
| US2705719A (en) * | 1953-11-06 | 1955-04-05 | Chemical Specialties Co Inc | Preparation of aromatic steroids and intermediates therefor |
| US2884418A (en) * | 1954-12-17 | 1959-04-28 | Syntex Sa | 19 nor spirostatriene and spirostatetraene intermediates |
| US3944584A (en) * | 1975-02-03 | 1976-03-16 | E. R. Squibb & Sons, Inc. | Steroidal (16α,17-d)cyclohexenes |
| FR2486947A1 (fr) * | 1980-07-15 | 1982-01-22 | Roussel Uclaf | Nouveaux derives steroides 20-isonitriles 17(20) insatures, leur procede de preparation et leur application a la preparation des steroides 17a-hydroxy 20-ceto |
| DE3109459A1 (de) * | 1981-03-09 | 1982-09-23 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | (delta)(pfeil hoch)9(pfeil hoch)(pfeil hoch)((pfeil hoch)(pfeil hoch)1(pfeil hoch)(pfeil hoch)1(pfeil hoch)(pfeil hoch))(pfeil hoch)- und (delta)(pfeil hoch)1(pfeil hoch)(pfeil hoch)6(pfeil hoch)-21-chlor-20-keto-steroide der pregnan- und d-homo-pregnan-reihe, verfahren zu ihrer herstellung und ihre verwendung als zwischenprodukte fuer die synthese von hochwirksamen corticoiden |
| EP0088831A1 (en) * | 1982-03-11 | 1983-09-21 | Gist-Brocades N.V. | Process for the preparation of thioethers |
| EP0123734A1 (en) * | 1983-04-29 | 1984-11-07 | Gist-Brocades N.V. | 17-(Isocyano-sulfonylmethylene)-steroids, 17-(formamido-sulfonylmethylene)-steroids and their preparation |
| EP0123736A1 (en) * | 1983-04-29 | 1984-11-07 | Gist-Brocades N.V. | New process for the preparation of 21-hydroxy-20-keto-delta 16-steroids and new intermediate compounds formed in this process |
-
1983
- 1983-04-29 EP EP83200617A patent/EP0123735A1/en not_active Withdrawn
-
1984
- 1984-04-19 AU AU27134/84A patent/AU567734B2/en not_active Ceased
- 1984-04-26 IL IL71660A patent/IL71660A/xx not_active IP Right Cessation
- 1984-04-27 US US06/604,734 patent/US4551278A/en not_active Expired - Lifetime
- 1984-04-27 JP JP59086021A patent/JPS59206398A/ja active Pending
- 1984-04-27 EP EP84200597A patent/EP0127217B1/en not_active Expired
- 1984-04-27 NZ NZ207987A patent/NZ207987A/en unknown
- 1984-04-27 FI FI841681A patent/FI82060C/fi not_active IP Right Cessation
- 1984-04-27 IE IE1040/84A patent/IE57252B1/en not_active IP Right Cessation
- 1984-04-27 PT PT78505A patent/PT78505B/pt not_active IP Right Cessation
- 1984-04-27 HU HU841663A patent/HU194907B/hu not_active IP Right Cessation
- 1984-04-27 DK DK212284A patent/DK166026C/da not_active IP Right Cessation
- 1984-04-27 KR KR1019840002249A patent/KR860001496B1/ko not_active Expired
- 1984-04-27 GR GR74532A patent/GR81988B/el unknown
- 1984-04-27 DE DE8484200597T patent/DE3474965D1/de not_active Expired
- 1984-04-27 CA CA000453028A patent/CA1291747C/en not_active Expired - Lifetime
- 1984-04-27 HU HU874318A patent/HU202552B/hu not_active IP Right Cessation
- 1984-04-27 NO NO841702A patent/NO167513C/no unknown
- 1984-04-28 ES ES532030A patent/ES8607985A1/es not_active Expired
-
1986
- 1986-02-01 ES ES551558A patent/ES8801837A1/es not_active Expired
-
1992
- 1992-01-08 JP JP4001728A patent/JPH0725792B2/ja not_active Expired - Lifetime
- 1992-02-21 DK DK022392A patent/DK167191B1/da active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20011110 |