ES8603500A1 - Procedimiento para la preparacion de nuevos derivados de triazolopirimidina. - Google Patents
Procedimiento para la preparacion de nuevos derivados de triazolopirimidina.Info
- Publication number
- ES8603500A1 ES8603500A1 ES542583A ES542583A ES8603500A1 ES 8603500 A1 ES8603500 A1 ES 8603500A1 ES 542583 A ES542583 A ES 542583A ES 542583 A ES542583 A ES 542583A ES 8603500 A1 ES8603500 A1 ES 8603500A1
- Authority
- ES
- Spain
- Prior art keywords
- opt
- substd
- alkylene
- alkyl
- heterocyclyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/50—Nitrogen atoms bound to hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE TRIAZOLOPIRIMIDINA Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE A REPRESENTA CH O NITROGENO; Y X Y R PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE DIAZOTACION DE UN COMPUESTO DE FORMULA (II), EN LA QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), O UNA SAL DEL MISMO, POR TRATAMIENTO CON UN NITRITO EN UN ACIDO O CON UN ESTER DE ACIDO NITROSO. LA DIAZOTACION SE EFECTUA CON AL MENOS, UNA CANTIDAD EQUIMOLECULAR DE NITRITO Y UN GRAN EXCESO DE ACIDO, ENFRIANDO CON HIELO, A UNA TEMPERATURA COMPRENDIDA ENTRE 1JC Y 30JC. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO Y PROFILAXIS DE ENFERMEDADES ALERGICAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59083232A JPS60226887A (ja) | 1984-04-25 | 1984-04-25 | トリアゾロピリミジン誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8603500A1 true ES8603500A1 (es) | 1985-12-16 |
| ES542583A0 ES542583A0 (es) | 1985-12-16 |
Family
ID=13796575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES542583A Granted ES542583A0 (es) | 1984-04-25 | 1985-04-25 | Procedimiento para la preparacion de nuevos derivados de triazolopirimidina. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4652646A (es) |
| EP (1) | EP0159707B1 (es) |
| JP (1) | JPS60226887A (es) |
| KR (1) | KR920002133B1 (es) |
| AT (1) | ATE49765T1 (es) |
| AU (1) | AU580050B2 (es) |
| CA (1) | CA1250836A (es) |
| DE (1) | DE3575562D1 (es) |
| DK (1) | DK181985A (es) |
| ES (1) | ES542583A0 (es) |
| FI (1) | FI81585C (es) |
| GR (1) | GR850995B (es) |
| IL (1) | IL75012A (es) |
| MX (1) | MX8232A (es) |
| NO (1) | NO170584C (es) |
| PH (1) | PH21387A (es) |
| PT (1) | PT80346B (es) |
| YU (1) | YU44048B (es) |
| ZA (1) | ZA853113B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL85207A (en) * | 1987-02-06 | 1992-06-21 | Daiichi Seiyaku Co | 6-substituted thiazolo-(and 1,3,4-thiadiazolo-)(3,2-a)-(1,2,3)triazolo(4,5-d)pyrimidin-9(1h)-ones and their preparation |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1338235A (en) * | 1970-12-15 | 1973-11-21 | May & Baker Ltd | Azapurinones |
| US4223031A (en) * | 1978-05-05 | 1980-09-16 | Mead Johnson & Company | Azolopyrimidinones |
| US4366156A (en) * | 1979-03-05 | 1982-12-28 | Mead Johnson & Company | Antiallergic methods using diazaheterocyclopurines |
-
1984
- 1984-04-25 JP JP59083232A patent/JPS60226887A/ja active Granted
-
1985
- 1985-04-19 CA CA000479642A patent/CA1250836A/en not_active Expired
- 1985-04-23 DK DK181985A patent/DK181985A/da not_active Application Discontinuation
- 1985-04-24 YU YU693/85A patent/YU44048B/xx unknown
- 1985-04-24 GR GR850995A patent/GR850995B/el unknown
- 1985-04-24 KR KR1019850002768A patent/KR920002133B1/ko not_active IP Right Cessation
- 1985-04-24 AT AT85104988T patent/ATE49765T1/de not_active IP Right Cessation
- 1985-04-24 FI FI851617A patent/FI81585C/fi not_active IP Right Cessation
- 1985-04-24 PT PT80346A patent/PT80346B/pt not_active IP Right Cessation
- 1985-04-24 IL IL75012A patent/IL75012A/xx unknown
- 1985-04-24 DE DE8585104988T patent/DE3575562D1/de not_active Expired - Lifetime
- 1985-04-24 AU AU41640/85A patent/AU580050B2/en not_active Ceased
- 1985-04-24 EP EP85104988A patent/EP0159707B1/en not_active Expired - Lifetime
- 1985-04-25 ZA ZA853113A patent/ZA853113B/xx unknown
- 1985-04-25 PH PH32187A patent/PH21387A/en unknown
- 1985-04-25 US US06/727,044 patent/US4652646A/en not_active Expired - Fee Related
- 1985-04-25 MX MX823285A patent/MX8232A/es unknown
- 1985-04-25 NO NO851654A patent/NO170584C/no unknown
- 1985-04-25 ES ES542583A patent/ES542583A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| PT80346A (en) | 1985-05-01 |
| DE3575562D1 (de) | 1990-03-01 |
| MX8232A (es) | 1993-12-01 |
| CA1250836A (en) | 1989-03-07 |
| JPH0421676B2 (es) | 1992-04-13 |
| AU4164085A (en) | 1985-10-31 |
| ZA853113B (en) | 1985-12-24 |
| FI81585B (fi) | 1990-07-31 |
| IL75012A0 (en) | 1985-08-30 |
| US4652646A (en) | 1987-03-24 |
| NO170584C (no) | 1992-11-04 |
| YU69385A (en) | 1987-10-31 |
| NO851654L (no) | 1985-10-28 |
| NO170584B (no) | 1992-07-27 |
| DK181985D0 (da) | 1985-04-23 |
| AU580050B2 (en) | 1988-12-22 |
| ES542583A0 (es) | 1985-12-16 |
| DK181985A (da) | 1985-10-26 |
| GR850995B (es) | 1985-11-25 |
| KR920002133B1 (ko) | 1992-03-12 |
| EP0159707B1 (en) | 1990-01-24 |
| YU44048B (en) | 1990-02-28 |
| EP0159707A3 (en) | 1986-10-22 |
| FI81585C (fi) | 1990-11-12 |
| EP0159707A2 (en) | 1985-10-30 |
| FI851617L (fi) | 1985-10-26 |
| PH21387A (en) | 1987-10-15 |
| PT80346B (pt) | 1987-06-17 |
| JPS60226887A (ja) | 1985-11-12 |
| IL75012A (en) | 1988-12-30 |
| KR850007602A (ko) | 1985-12-07 |
| FI851617A0 (fi) | 1985-04-24 |
| ATE49765T1 (de) | 1990-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970303 |