ES8602773A1 - Procedimiento para la fabricacion de derivados del dioxolano de tipo azolico - Google Patents

Procedimiento para la fabricacion de derivados del dioxolano de tipo azolico

Info

Publication number
ES8602773A1
ES8602773A1 ES534484A ES534484A ES8602773A1 ES 8602773 A1 ES8602773 A1 ES 8602773A1 ES 534484 A ES534484 A ES 534484A ES 534484 A ES534484 A ES 534484A ES 8602773 A1 ES8602773 A1 ES 8602773A1
Authority
ES
Spain
Prior art keywords
alkyl
triazol
derivatives
alkoxy
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES534484A
Other languages
English (en)
Other versions
ES534484A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of ES534484A0 publication Critical patent/ES534484A0/es
Publication of ES8602773A1 publication Critical patent/ES8602773A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

PROCEDIMIENTO PARA LA FABRICACION DE DERIVADOS DEL DIOXOLANO DE TIPO AZOLICO. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN AGENTE CICLIZANTE, SELECCIONADO ENTRE: DIALOMETANO, ESTER DE ACIDO HALOCARBONICO, UNA ACETONA/SU DIMETILCETAL, UN HALURO DE TIONILO, 1,1-TIOCARBONILDIIMIDAZOL Y TIOFOSGENO; LA REACCION SE LLEVA A CABO EN PRESENCIA DE UNA BASE, COMO HIDRURO SODICO, TRIETILAMINA, PIRIDINA, 2,6-LUTIDINA, O GAMMA-PICOLINA, Y UN DISOLVENTE, COMO CLOROFORMO, Y A UNA TEMPERATURA ENTRE 0 Y 150C, PARA OBTENER UN COMPUESTO DE FORMULA (I). SIENDO: R, ALQUILO O FENILO DE C 1 A 5; R1 Y R2, H, ALQUILO DE C 1 A 3 Y OTROS; X1 Y X2, H, HAL Y OTROS; E Y, C O,C S,S O, O R1-C-R2. SE UTILIZAN EN FARMACOLOGIA COMO ANTIMICOTICOS.
ES534484A 1983-07-20 1984-07-20 Procedimiento para la fabricacion de derivados del dioxolano de tipo azolico Expired ES8602773A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58133040A JPS6025990A (ja) 1983-07-20 1983-07-20 トリアゾ−ル系ジオキソラン誘導体

Publications (2)

Publication Number Publication Date
ES534484A0 ES534484A0 (es) 1985-12-01
ES8602773A1 true ES8602773A1 (es) 1985-12-01

Family

ID=15095402

Family Applications (1)

Application Number Title Priority Date Filing Date
ES534484A Expired ES8602773A1 (es) 1983-07-20 1984-07-20 Procedimiento para la fabricacion de derivados del dioxolano de tipo azolico

Country Status (9)

Country Link
US (1) US4612322A (es)
EP (1) EP0133248B1 (es)
JP (1) JPS6025990A (es)
KR (1) KR910009200B1 (es)
CA (1) CA1244039A (es)
DE (1) DE3485281D1 (es)
DK (1) DK160826C (es)
ES (1) ES8602773A1 (es)
GB (1) GB2144124B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4788190A (en) * 1986-12-24 1988-11-29 Schering Corporation 2,4,4-tri- and 2,2,4,4-tetra substituted-1,3-dioxolane antifungal, antiallergy compounds
DE3805376A1 (de) * 1988-02-20 1989-08-31 Basf Ag Neue azolylmethyloxirane und diese enthaltende fungizide
JPH0349799A (ja) * 1989-07-18 1991-03-04 Sanyo Electric Co Ltd 洗濯機
JPH0826012B2 (ja) * 1991-08-23 1996-03-13 呉羽化学工業株式会社 新規な１，３，２−ジオキサチオランｓ酸化物誘導体、その製造方法及びその用途
DE59310066D1 (de) * 1992-11-04 2000-08-03 Clariant Gmbh Verfahren zur Herstellung fluorierter Benzile
US5686061A (en) * 1994-04-11 1997-11-11 The Board Of Regents Of The University Of Texas System Particulate contrast media derived from non-ionic water soluble contrast agents for CT enhancement of hepatic tumors
CA2139079C (en) * 1994-12-23 1996-05-28 K.S. Keshava Murthy Commercial process for the manufacture of fluconazole and intermediates useful in the manufacture thereof
IT1296926B1 (it) * 1997-12-05 1999-08-03 Zambon Spa Procedimento per la preparazione di composti ad attivita' antimicotica
KR100458866B1 (ko) * 1999-05-21 2004-12-03 한국화학연구원 1,3-디옥솔란-2-일리덴 유도체 및 그의 제조 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2095236B (en) * 1981-03-18 1985-03-27 Ici Plc Heterocyclylmethyl-substituted dioxolanes and their use as fungicides
JPS58128383A (ja) * 1982-01-26 1983-07-30 Sumitomo Chem Co Ltd トリアゾ−ル系化合物、その製造法およびこれを有効成分として含有する農園芸用殺菌剤、植物生長調節剤または除草剤
EP0094167A3 (en) * 1982-05-12 1984-07-04 Fbc Limited Azolyl fungicide and plant growth regulators and compositions containing them
EP0106515B1 (en) * 1982-09-30 1988-12-28 Pfizer Limited Triazole anti-fungal agents
FI834141A (fi) * 1982-11-16 1984-05-17 Ciba Geigy Ag Foerfarande foer framstaellning av nya arylfenyleterderivat.
JPS59212491A (ja) * 1983-05-17 1984-12-01 Sumitomo Chem Co Ltd トリアゾ−ル系化合物、その製造法およびそれを有効成分とする農園芸用殺菌剤

Also Published As

Publication number Publication date
KR910009200B1 (ko) 1991-11-04
DK354684D0 (da) 1984-07-19
DE3485281D1 (de) 1992-01-02
EP0133248A2 (en) 1985-02-20
JPS6025990A (ja) 1985-02-08
GB2144124B (en) 1987-04-01
CA1244039A (en) 1988-11-01
US4612322A (en) 1986-09-16
GB2144124A (en) 1985-02-27
JPH0417957B2 (es) 1992-03-26
ES534484A0 (es) 1985-12-01
DK160826C (da) 1991-10-14
EP0133248B1 (en) 1991-11-21
KR850001200A (ko) 1985-03-16
DK354684A (da) 1985-01-21
GB8418575D0 (en) 1984-08-22
EP0133248A3 (en) 1987-12-23
DK160826B (da) 1991-04-22

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001