ES8602418A1 - Un procedimiento para preparar composiciones farmaceuticas de disolucion rapida que contienen como ingrediente activo triamteremo o metolazona. - Google Patents

Un procedimiento para preparar composiciones farmaceuticas de disolucion rapida que contienen como ingrediente activo triamteremo o metolazona.

Info

Publication number
ES8602418A1
ES8602418A1 ES531978A ES531978A ES8602418A1 ES 8602418 A1 ES8602418 A1 ES 8602418A1 ES 531978 A ES531978 A ES 531978A ES 531978 A ES531978 A ES 531978A ES 8602418 A1 ES8602418 A1 ES 8602418A1
Authority
ES
Spain
Prior art keywords
preparation
rapid dissolving
drug compositions
uniform drug
rapid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES531978A
Other languages
English (en)
Other versions
ES531978A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pennwalt Corp
Original Assignee
Pennwalt Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pennwalt Corp filed Critical Pennwalt Corp
Publication of ES531978A0 publication Critical patent/ES531978A0/es
Publication of ES8602418A1 publication Critical patent/ES8602418A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Abstract

PROCEDIMIENTO PARA PREPARAR COMPOSICIONES FARMACEUTICAS DE DISOLUCION RAPIDA QUE CONTIENEN COMO INGREDIENTE ACTIVO TRIAMTERENO O METOLAZONA. COMPRENDE: A) MEZCLAR ALMIDONES UTILIZADOS COMO UNO DE LOS EXCIPIENTES DE LA COMPOSICION FARMACEUTICA DURANTE 10 MINUTOS; B) MOLER FINAMENTE Y TAMIZAR POR SEPARADO EL INGREDIENTE ACTIVO PARA OBTENER UNA DISTRIBUCION DE TAMAÑOS DE PARTICULAS INFERIORES A 155 NM; C) DILUIR GEOMETRICAMENTE EL INGREDIENTE ACTIVO TAMIZADO EN LA MEZCLA DE ALMIDONES DE (A) DURANTE 5 A 15 MINUTOS; D) MEZCLAR POR SEPARADO CELULOSA MICROCRISTALINA Y FOSFATO CALCICO DIBASICO UTILIZADOS COMO OTROS EXCIPIENTES DE LA COMPOSICION FARMACEUTICA DURANTE 5 A 10 MINUTOS; E) AÑADIR LA DISOLUCION GEOMETRICA DEL INGREDIENTE ACTIVO Y LOS ALMIDONES A LA MEZCLA DE EXCIPIENTES DURANTE 5 A 15 MINUTOS; F) INCORPORAR UN LUBRICANTE EN LA MASA OBTENIDA EN (E) Y AGITAR DURANTE 1 A 3 MINUTOS PARA OBTENER UNA MEZCLA HOMOGENEA SECA DE FLUIDEZ LIBRE Y UNIFORME; Y G) COMPRIMIR LA MEZCLA PARA FORMAR TABLETAS O CARGARLA EN CAPSULAS. LAS PROPORCIONES EN PESO SON 0,05 A 12,5% DEL INGREDIENTE ACTIVO, 10 A 90% DE CELULOSA MICROCRISTALINA, 1 A 20% DE ALMIDONES, 10 A 90% DE FOSFATO CALCICO DIBASICO Y 0,1 A 3% DEL LUBRICANTE.
ES531978A 1983-04-29 1984-04-27 Un procedimiento para preparar composiciones farmaceuticas de disolucion rapida que contienen como ingrediente activo triamteremo o metolazona. Expired ES8602418A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49005683A 1983-04-29 1983-04-29
US06/586,605 US4517179A (en) 1983-04-29 1984-03-06 Rapid dissolving, uniform drug compositions and their preparation

Publications (2)

Publication Number Publication Date
ES531978A0 ES531978A0 (es) 1985-12-01
ES8602418A1 true ES8602418A1 (es) 1985-12-01

Family

ID=27049920

Family Applications (1)

Application Number Title Priority Date Filing Date
ES531978A Expired ES8602418A1 (es) 1983-04-29 1984-04-27 Un procedimiento para preparar composiciones farmaceuticas de disolucion rapida que contienen como ingrediente activo triamteremo o metolazona.

Country Status (13)

Country Link
US (1) US4517179A (es)
EP (1) EP0124027B1 (es)
AU (1) AU565640B2 (es)
CA (1) CA1216236A (es)
CH (1) CH662947A5 (es)
DE (1) DE3482402D1 (es)
DK (1) DK162630C (es)
ES (1) ES8602418A1 (es)
FI (1) FI85215C (es)
IE (1) IE57137B1 (es)
IL (1) IL71506A (es)
NZ (1) NZ207678A (es)
PT (1) PT78395B (es)

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US4818539A (en) * 1985-02-05 1989-04-04 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4790991A (en) * 1985-02-05 1988-12-13 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4843098A (en) * 1985-02-05 1989-06-27 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4747881A (en) * 1985-02-05 1988-05-31 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4684534A (en) * 1985-02-19 1987-08-04 Dynagram Corporation Of America Quick-liquifying, chewable tablet
US5028633A (en) * 1985-02-21 1991-07-02 Freund Industrial Co., Ltd. Excipient for use in compression molding and process of preparation
US4744987A (en) * 1985-03-08 1988-05-17 Fmc Corporation Coprocessed microcrystalline cellulose and calcium carbonate composition and its preparation
US4707361A (en) * 1985-08-02 1987-11-17 Stauffer Chemical Company Granular anhydrous dicalcium phosphate compositions suitable for direct compression tableting
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
US4677130A (en) * 1985-10-07 1987-06-30 Great Lakes Chemical Corporation Process of densification of N-halohydantoin compositions and products thereof
EP0418597A3 (en) * 1989-09-21 1991-11-27 American Cyanamid Company Controlled release carbonic anhydrase inhibitor containing pharmaceutical compositions from spherical granules in capsule oral dosage unit form
HU206824B (en) * 1990-08-24 1993-01-28 Biogal Gyogyszergyar Process for the production of a table crystallizing in the monoclinic system, which contains light-, heat-, and moisture- sensitive active agents
US5643591A (en) * 1991-01-16 1997-07-01 Fmc Corporation Solid dosage forms
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
SK282071B6 (sk) * 1991-01-30 2001-10-08 The Wellcome Foundation Limited Tableta dispergovateľná vo vode a spôsob jej prípravy
DE69233130T2 (de) * 1991-05-28 2005-06-02 Mcneil-Ppc, Inc. Kaubare zusammensetzung zur arzneimittelfreisetzung
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
AU687744B2 (en) * 1993-05-15 1998-03-05 Riemser Arzneimittel Ag More easily biologically absorbed tablet containing dichloromethylene diphosphonic acid as the active agent
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
EP1057479A1 (en) * 1994-12-14 2000-12-06 Enbalt Trading Limited Pharmaceutical tablet formulations for direct compression
DE19530575A1 (de) * 1995-08-19 1997-02-20 Gruenenthal Gmbh Schnell zerfallende Arzneiform von Tramadol oder einem Tramadolsalz
US5807577A (en) * 1995-11-22 1998-09-15 Lab Pharmaceutical Research International Inc. Fast-melt tablet and method of making same
US5807578A (en) * 1995-11-22 1998-09-15 Lab Pharmaceutical Research International Inc. Fast-melt tablet and method of making same
US6037380A (en) * 1997-04-11 2000-03-14 Fmc Corporation Ultra-fine microcrystalline cellulose compositions and process
AR016827A1 (es) 1997-08-22 2001-08-01 Smithkline Beecham Corp PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA
AR017512A1 (es) 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
SE9802973D0 (sv) * 1998-09-03 1998-09-03 Astra Ab Immediate release tablet
AU1323400A (en) * 1998-10-27 2000-05-15 Fuisz Technologies Ltd. Microparticles containing peg and/or peg glyceryl esters
US7815937B2 (en) * 1998-10-27 2010-10-19 Biovail Laboratories International Srl Quick dissolve compositions and tablets based thereon
US6552024B1 (en) 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
US6048874A (en) * 1999-01-26 2000-04-11 Medeva Pharmaceuticals Manufacturing, Inc. Parenteral metolazone formulations
JP2003518485A (ja) 1999-12-23 2003-06-10 ファイザー・プロダクツ・インク 向上された薬物濃度を与える医薬組成物
US6602523B1 (en) * 2000-08-17 2003-08-05 Technology Holding, Llc. Composite material and process for increasing bioavailability and activity of a beneficial agent
US6462022B1 (en) * 2001-09-24 2002-10-08 Astrazeneca Ab Lisinopril compositions having large-particle DCPD
US20040048931A1 (en) * 2002-07-12 2004-03-11 Craig Heacock Modafinil pharmaceutical compositions
JP2006514687A (ja) * 2002-08-30 2006-05-11 ファルマシア コーポレイション 再現性のある医薬放出特性を示す医薬固形投与形態
US20040265375A1 (en) * 2003-04-16 2004-12-30 Platteeuw Johannes J. Orally disintegrating tablets
US20040253308A1 (en) * 2003-04-29 2004-12-16 Barr Laboratories, Inc. Surface-treated modafinil particles
WO2005011695A1 (en) * 2003-07-31 2005-02-10 The Administrators Of The Tulane Educational Fund Method of treating preeclampsia employing metolazone
JP5026077B2 (ja) 2003-09-12 2012-09-12 アムジエン・インコーポレーテツド カルシウム受容体−活性化合物の急速溶解処方
US7344907B2 (en) * 2004-11-19 2008-03-18 International Business Machines Corporation Apparatus and methods for encapsulating microelectromechanical (MEM) devices on a wafer scale
US20080058408A1 (en) 2006-05-19 2008-03-06 Rogowski Roberta L Low-dose doxepin for treatment of sleep disorders in elderly patients
JP2009537554A (ja) * 2006-05-19 2009-10-29 ソマクソン ファーマシューティカルズ インコーポレイテッド 不眠症を治療するための、口腔内、舌下および急速融解製剤を含む、低用量ドキセピン製剤、ならびにその使用
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US20080145423A1 (en) * 2006-12-14 2008-06-19 Ajmal Ali Khan Chewable tablet and method of formulating
EP1977734A1 (en) * 2007-04-03 2008-10-08 Royal College of Surgeons in Ireland A method of producing fast dissolving tablets
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TWI461213B (zh) * 2009-11-05 2014-11-21 Fmc Corp 作為藥物賦形劑之微晶纖維素及磷酸鈣之組合物
US11052049B2 (en) * 2019-04-11 2021-07-06 Atoz Pharmaceuticals Pvt Ltd Capsule dosage forms of triamterene, and process of preparation thereof

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US3360518A (en) * 1966-01-03 1967-12-26 Wallace & Tiernan Inc Tetrahydro-halo-sulfamyl quinazolinones
NL6701470A (es) * 1966-02-03 1967-08-04
US3745216A (en) * 1969-12-18 1973-07-10 Smith Kline French Lab Compositions and methods for producing hypotensive activity with imidazo and pyrimido(2,1-b)quinazoline compounds
DE2416903A1 (de) * 1974-04-06 1975-10-09 Bayer Ag Verwendung von schmelzverspruehtem kugelfoermigem phenacetingranulat zur herstellung von tabletten im direkttablettierverfahren
DE2658500C2 (de) * 1976-12-23 1986-10-09 Knoll Ag, 6700 Ludwigshafen Pharmazeutische Präparate mit kardioprotektiver Wirkung
EP0047734A1 (en) * 1980-03-10 1982-03-24 Edward Mendell Co., Inc. Pharmaceutical vehicle composition and process of producing same
DE3012862A1 (de) * 1980-04-02 1981-10-08 Cassella Ag, 6000 Frankfurt Substituierte 1,2,5-oxdiazol-2-oxide als pharmazeutische wirkstoffe, ihre verwendung und sie enthaltende arzneimittel
DE3107933A1 (de) * 1981-03-02 1982-09-16 Cassella Ag, 6000 Frankfurt Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung

Also Published As

Publication number Publication date
AU565640B2 (en) 1987-09-24
IL71506A (en) 1987-09-16
FI841696A0 (fi) 1984-04-27
PT78395A (en) 1984-05-01
US4517179A (en) 1985-05-14
DK162630C (da) 1992-04-13
IL71506A0 (en) 1984-07-31
CA1216236A (en) 1987-01-06
DK162630B (da) 1991-11-25
EP0124027B1 (en) 1990-06-06
DK211084D0 (da) 1984-04-27
EP0124027A1 (en) 1984-11-07
DK211084A (da) 1984-10-30
FI841696A (fi) 1984-10-30
FI85215B (fi) 1991-12-13
IE840735L (en) 1984-10-29
ES531978A0 (es) 1985-12-01
DE3482402D1 (de) 1990-07-12
IE57137B1 (en) 1992-05-06
AU2643484A (en) 1984-11-01
NZ207678A (en) 1986-11-12
CH662947A5 (de) 1987-11-13
FI85215C (fi) 1992-03-25
PT78395B (en) 1986-06-02

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303