ES8307230A1 - "un procedimiento para la preparacion de oxaprocin calcico". - Google Patents
"un procedimiento para la preparacion de oxaprocin calcico".Info
- Publication number
- ES8307230A1 ES8307230A1 ES511730A ES511730A ES8307230A1 ES 8307230 A1 ES8307230 A1 ES 8307230A1 ES 511730 A ES511730 A ES 511730A ES 511730 A ES511730 A ES 511730A ES 8307230 A1 ES8307230 A1 ES 8307230A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- oxazole derivatives
- oxaprozin
- calcium
- palatable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
UN PROCEDIMIENTO PARA LA PREPARACION DE OXAPROCIN CALCICO. SE HACE REACCIONAR OXAPROZIN PERFECTAMENTE EN FORMA DE SAL SOLUBLE CON UNA FUENTE DE IONES CALCIO; PREFERENTEMENTE SE EMPLEA UNA SAL DE METAL ALCALINO DE OXAPROZIN Y UNA SAL CALCICA ACUOSOLUBLE TAL COMO CLORURO CALCICO EN SOLUCION ACUOSA, DE DONDE SE AISLA EL OXAPROZIN OBTENIDO. PREFERENTEMENTE SE OBTIENE OXAPROZIN TETRAHIDRATADOS. EL COMPONENTE ACTIVO PUEDE SUSPENDERSE EN UN VEHICULO LIQUIDO FARMACEUTICAMENTE ACEPTABLE TAL COMO EL AGUA, UN DISOLVENTE ORGANICO, UNA MEZCLA DE AMBOS O ACEITES O GRASAS FARMACEUTICAMENTE ACEPTABLES. LAS COMPOSICIONES EN FORMA LIQUIDA INCLUYEN SUSPENSIONES, EMULSIONES, JARABES O ELIXIRES. ACTIVIDAD ANTI-INFLAMATORIA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8113074 | 1981-04-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8307230A1 true ES8307230A1 (es) | 1983-07-01 |
ES511730A0 ES511730A0 (es) | 1983-07-01 |
Family
ID=10521427
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES511730A Granted ES511730A0 (es) | 1981-04-28 | 1982-04-27 | "un procedimiento para la preparacion de oxaprocin calcico". |
Country Status (24)
Country | Link |
---|---|
US (2) | US4465838A (es) |
EP (1) | EP0063884B1 (es) |
JP (1) | JPS57181072A (es) |
KR (1) | KR880000871B1 (es) |
AT (1) | ATE14015T1 (es) |
AU (1) | AU544975B2 (es) |
CA (1) | CA1169867A (es) |
CS (1) | CS236674B2 (es) |
DD (1) | DD202017A5 (es) |
DE (1) | DE3264400D1 (es) |
DK (1) | DK150604C (es) |
ES (1) | ES511730A0 (es) |
FI (1) | FI71314C (es) |
GR (1) | GR75913B (es) |
HU (1) | HU185276B (es) |
IE (1) | IE52909B1 (es) |
IL (1) | IL65443A (es) |
MY (1) | MY8700599A (es) |
NZ (1) | NZ200247A (es) |
PH (1) | PH18053A (es) |
PL (1) | PL136322B1 (es) |
PT (1) | PT74794B (es) |
ZA (1) | ZA822355B (es) |
ZW (1) | ZW7482A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5380738A (en) * | 1993-05-21 | 1995-01-10 | Monsanto Company | 2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents |
US6726928B2 (en) * | 1994-10-28 | 2004-04-27 | R.P. Scherer Technologies, Inc. | Process for preparing solid dosage forms for unpalatable pharmaceuticals |
KR20000015865A (ko) * | 1996-05-20 | 2000-03-15 | 윌리암스 로저 에이 | 칼륨, 나트륨 및 트리스옥사프로진염의 약학적 제제 |
US7358254B2 (en) * | 2001-07-13 | 2008-04-15 | Bristol-Myers Squibb Company | Method for treating atherosclerosis employing an aP2 inhibitor and combination |
US20060251689A1 (en) * | 2005-03-30 | 2006-11-09 | Astion Development A/S | Treatment or prevention of pruritus |
AU2006228869A1 (en) * | 2005-03-30 | 2006-10-05 | Astion Pharma A/S | Oxaprozin or a closely related compound for the treatment of eczema |
WO2010023621A2 (en) * | 2008-08-26 | 2010-03-04 | Dorf Ketal Chemicals (I) Pvt. Ltd. | A new additive for inhibiting acid corrosion and method of using the new additive |
KR20140065862A (ko) * | 2012-11-22 | 2014-05-30 | 에스케이케미칼주식회사 | 발포성 속붕해성 이매티닙 제제 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1206403A (en) * | 1966-12-15 | 1970-09-23 | Wyeth John & Brother Ltd | Oxazoles |
GB1245087A (en) * | 1967-10-26 | 1971-09-02 | Wyeth John & Brother Ltd | Heterocyclic compounds |
US3578671A (en) * | 1967-11-06 | 1971-05-11 | Wyeth John & Brother Ltd | Oxazoles |
-
1982
- 1982-03-31 IE IE766/82A patent/IE52909B1/en not_active IP Right Cessation
- 1982-04-05 ZA ZA822355A patent/ZA822355B/xx unknown
- 1982-04-05 CA CA000400464A patent/CA1169867A/en not_active Expired
- 1982-04-06 IL IL65443A patent/IL65443A/xx not_active IP Right Cessation
- 1982-04-06 AU AU82378/82A patent/AU544975B2/en not_active Expired
- 1982-04-06 NZ NZ200247A patent/NZ200247A/en unknown
- 1982-04-07 DE DE8282301839T patent/DE3264400D1/de not_active Expired
- 1982-04-07 AT AT82301839T patent/ATE14015T1/de not_active IP Right Cessation
- 1982-04-07 EP EP82301839A patent/EP0063884B1/en not_active Expired
- 1982-04-09 GR GR67879A patent/GR75913B/el unknown
- 1982-04-15 ZW ZW74/82A patent/ZW7482A1/xx unknown
- 1982-04-15 FI FI821324A patent/FI71314C/fi not_active IP Right Cessation
- 1982-04-22 PH PH27171A patent/PH18053A/en unknown
- 1982-04-23 JP JP57069463A patent/JPS57181072A/ja active Granted
- 1982-04-23 DK DK183582A patent/DK150604C/da not_active IP Right Cessation
- 1982-04-26 PL PL1982236145A patent/PL136322B1/pl unknown
- 1982-04-26 PT PT74794A patent/PT74794B/pt unknown
- 1982-04-26 US US06/371,904 patent/US4465838A/en not_active Expired - Lifetime
- 1982-04-26 KR KR8201829A patent/KR880000871B1/ko active
- 1982-04-27 DD DD82239350A patent/DD202017A5/de not_active IP Right Cessation
- 1982-04-27 ES ES511730A patent/ES511730A0/es active Granted
- 1982-04-27 HU HU821325A patent/HU185276B/hu unknown
- 1982-04-28 CS CS823052A patent/CS236674B2/cs unknown
-
1984
- 1984-07-11 US US06/629,704 patent/US4532253A/en not_active Expired - Lifetime
-
1987
- 1987-12-30 MY MY599/87A patent/MY8700599A/xx unknown
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