ES8601942A1 - Un procedimiento para la preparacion de nuevos derivados de benzotiazina - Google Patents

Un procedimiento para la preparacion de nuevos derivados de benzotiazina

Info

Publication number
ES8601942A1
ES8601942A1 ES529462A ES529462A ES8601942A1 ES 8601942 A1 ES8601942 A1 ES 8601942A1 ES 529462 A ES529462 A ES 529462A ES 529462 A ES529462 A ES 529462A ES 8601942 A1 ES8601942 A1 ES 8601942A1
Authority
ES
Spain
Prior art keywords
benzothiazine derivatives
benzothiazine
derivatives
salts
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES529462A
Other languages
English (en)
Other versions
ES529462A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Santen Pharmaceutical Co Ltd
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP58019467A external-priority patent/JPS59144775A/ja
Priority claimed from JP58020990A external-priority patent/JPS59148771A/ja
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of ES529462A0 publication Critical patent/ES529462A0/es
Publication of ES8601942A1 publication Critical patent/ES8601942A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE BENZOTIAZINA, DE FORMULA GENERAL (I), EN LA QUE R1 SIGNIFICA HIDROGENO, HIDROXI, O ALCOXI; R2 SIGNIFICA HIDROGENO, NITRO O HIDROXI; Y R3 ES HIDROGENO, Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. CONSISTE EN HACER REACCIONAR UN HALURO DE FORMULA GENERAL (II), CON UN COMPUESTO DE FORMULA GENERAL (III), EN LAS QUE X ES HALOGENO O METANOSULFONILOXI. DE APLICACION EN FARMACIA Y MEDICINA, PREFERENTEMENTE EN EL TRATAMIENTO DE LAS AFECCIONES CARDIOVASCULARES, TALES COMO LA ANGINA DE PECHO, LA ARRITMIA Y LA TROMBOSIS.
ES529462A 1983-02-07 1984-02-03 Un procedimiento para la preparacion de nuevos derivados de benzotiazina Expired ES8601942A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58019467A JPS59144775A (ja) 1983-02-07 1983-02-07 ヒドロキシフエニルベンゾチアジン誘導体およびその製造法
JP58020990A JPS59148771A (ja) 1983-02-09 1983-02-09 ベンゾチアジン誘導体

Publications (2)

Publication Number Publication Date
ES529462A0 ES529462A0 (es) 1985-11-01
ES8601942A1 true ES8601942A1 (es) 1985-11-01

Family

ID=26356296

Family Applications (2)

Application Number Title Priority Date Filing Date
ES529462A Expired ES8601942A1 (es) 1983-02-07 1984-02-03 Un procedimiento para la preparacion de nuevos derivados de benzotiazina
ES544140A Expired ES8706654A1 (es) 1983-02-07 1985-06-13 Un procedimiento para la preparacion de nuevos derivados de benzotiazina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES544140A Expired ES8706654A1 (es) 1983-02-07 1985-06-13 Un procedimiento para la preparacion de nuevos derivados de benzotiazina

Country Status (10)

Country Link
US (1) US4584300A (es)
EP (1) EP0116368B1 (es)
KR (1) KR910005706B1 (es)
AU (1) AU570667B2 (es)
CA (1) CA1245650A (es)
DE (1) DE3466987D1 (es)
DK (1) DK160150C (es)
ES (2) ES8601942A1 (es)
FI (1) FI81344C (es)
NO (1) NO164169C (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3347173A1 (de) * 1983-12-27 1985-07-04 Hoechst Ag, 6230 Frankfurt Neue benzothiazin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
IE58312B1 (en) * 1984-05-18 1993-09-08 Union Pharma Scient Appl Heterocyclic derivatives, processes for their preparation and drugs in which they are present, which are useful especially as aldose reductase inhibitors
EP0186310A1 (en) * 1984-11-28 1986-07-02 Takeda Chemical Industries, Ltd. 1,4-Benzothiazine Derivatives, their production and use
US4786635A (en) * 1985-07-29 1988-11-22 Santen Pharmaceutical Co., Ltd. Novel benzothiazine derivatives
WO1987000837A1 (en) * 1985-07-29 1987-02-12 Santen Pharmaceutical Co., Ltd Novel benzothiazine derivatives
DE3529994A1 (de) * 1985-08-22 1987-02-26 Hoechst Ag Indolinonderivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DE3614355A1 (de) * 1986-04-28 1987-10-29 Hoechst Ag Neue benzothiazinon-derivate, verfahren zu ihrer herstellung , sie enthaltende arzneimittel und deren verwendung
DE3614363A1 (de) * 1986-04-28 1987-10-29 Hoechst Ag Benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DE3724366A1 (de) * 1987-07-23 1989-02-02 Hoechst Ag Benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DE3726759A1 (de) * 1987-08-12 1989-03-09 Hoechst Ag Benzothiazinon-oxide, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung sowie zwischenprodukte zu ihrer herstellung
CA2035147A1 (en) * 1990-02-08 1991-08-09 Kousuke Yasuda Thiazine (or oxazine) derivatives and preparation thereof
US5496815A (en) * 1990-02-08 1996-03-05 Tanabe Seiyaku Co., Ltd. Thiazine (or oxazine) derivatives and preparation thereof
TW213468B (es) * 1991-06-29 1993-09-21 Hoechst Ag
US5547952A (en) * 1993-12-09 1996-08-20 Santen Pharmaceutical Co., Ltd. 3-oxo-1,4-benzothiazine derivatives
KR20010042296A (ko) * 1998-03-31 2001-05-25 로즈 암스트롱, 크리스틴 에이. 트러트웨인 세린 프로테아제 억제제로서의 벤즈옥사지논/벤조티아지논
US6713477B1 (en) 2000-04-19 2004-03-30 Sumitomo Pharmaceuticals Company, Limited Hydroxamic acid derivatives
EP1726587B1 (en) * 2004-03-02 2010-09-01 Dainippon Sumitomo Pharma Co., Ltd. Benzothiazin-3-one compound and intermediate therefor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3166554A (en) * 1965-01-19 Certificate of correction
US3555155A (en) * 1968-06-03 1971-01-12 Squibb & Sons Inc Method of controlling insects
US3923709A (en) * 1974-08-30 1975-12-02 Monsanto Co 3,4-Dihydro-3-oxo-2H-1,4-benzothiazines and benzoxazines
US4078062A (en) * 1976-10-28 1978-03-07 E. R. Squibb & Sons, Inc. Substituted 2H-1,4-benzothiazin-3(4H)-ones
DE3347173A1 (de) * 1983-12-27 1985-07-04 Hoechst Ag, 6230 Frankfurt Neue benzothiazin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung

Also Published As

Publication number Publication date
AU2376784A (en) 1984-08-16
ES529462A0 (es) 1985-11-01
FI81344B (fi) 1990-06-29
EP0116368B1 (en) 1987-10-28
US4584300A (en) 1986-04-22
NO164169B (no) 1990-05-28
DK160150B (da) 1991-02-04
AU570667B2 (en) 1988-03-24
DK53784A (da) 1984-08-08
KR840007592A (ko) 1984-12-08
FI840482A0 (fi) 1984-02-06
DE3466987D1 (de) 1987-12-03
FI840482A (fi) 1984-08-08
NO164169C (no) 1990-09-05
EP0116368A1 (en) 1984-08-22
ES8706654A1 (es) 1987-07-01
FI81344C (fi) 1990-10-10
CA1245650A (en) 1988-11-29
ES544140A0 (es) 1987-07-01
KR910005706B1 (ko) 1991-08-02
DK160150C (da) 1991-07-01
DK53784D0 (da) 1984-02-07
NO840434L (no) 1984-08-08

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20040601