ES8601083A1 - Un procedimiento para la preparacion de nuevos derivados del terfenilo. - Google Patents

Un procedimiento para la preparacion de nuevos derivados del terfenilo.

Info

Publication number
ES8601083A1
ES8601083A1 ES533553A ES533553A ES8601083A1 ES 8601083 A1 ES8601083 A1 ES 8601083A1 ES 533553 A ES533553 A ES 533553A ES 533553 A ES533553 A ES 533553A ES 8601083 A1 ES8601083 A1 ES 8601083A1
Authority
ES
Spain
Prior art keywords
terphenyl derivatives
terphenyl
derivatives
derivs
substd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES533553A
Other languages
English (en)
Other versions
ES533553A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES533553A0 publication Critical patent/ES533553A0/es
Publication of ES8601083A1 publication Critical patent/ES8601083A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/516—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of nitrogen-containing compounds to >C = O groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
    • C07C43/2055—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring containing more than one ether bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS DERIVADOS DE TERFENILO. CONSISTE EN DESHIDROGENAR UN COMPUESTO DE FORRMULA (II) CON UN REACTIVO DE DESHIDROGENACION COMO PALADIO EN CARBON DIOXIDO DE MANGANESO CLORANILO O DDQ EN UN DISOLVENTE COMO BENCENO O TOLUENO Y A TEMPERATURAS ENTRE 30JC Y LA TEMPERATURA DE REFLUJO DE LA SOLUCION PARA OBTENER EL FRIORILBENCENO DERIVADO DE FORMULA (I). SIENDO: R UN FENILO O FENILO SUSTITUIDO CON YODO BROMO CLORO FLUOR O TRIFLUORMETILO. SE UTILIZAN PARA EL TRATAMIENTO DEL DOLOR LA FIEBRE LA TROMBOSIS LA INFLAMACION Y LA ARTRITIS EN LOS MAMIFEROS.
ES533553A 1983-06-22 1984-06-19 Un procedimiento para la preparacion de nuevos derivados del terfenilo. Expired ES8601083A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/506,931 US4495202A (en) 1983-06-22 1983-06-22 Terphenyl derivatives and pharmaceutical uses thereof

Publications (2)

Publication Number Publication Date
ES533553A0 ES533553A0 (es) 1985-10-16
ES8601083A1 true ES8601083A1 (es) 1985-10-16

Family

ID=24016546

Family Applications (1)

Application Number Title Priority Date Filing Date
ES533553A Expired ES8601083A1 (es) 1983-06-22 1984-06-19 Un procedimiento para la preparacion de nuevos derivados del terfenilo.

Country Status (20)

Country Link
US (1) US4495202A (es)
EP (1) EP0130045B1 (es)
JP (1) JPS6013730A (es)
KR (1) KR870000199B1 (es)
AT (1) ATE25072T1 (es)
AU (1) AU566411B2 (es)
CA (1) CA1246621A (es)
DD (1) DD217799A5 (es)
DE (1) DE3462129D1 (es)
DK (1) DK300684A (es)
ES (1) ES8601083A1 (es)
FI (1) FI842477A (es)
GB (1) GB2142024B (es)
GR (1) GR82376B (es)
HU (1) HU194528B (es)
IL (1) IL72146A (es)
NZ (1) NZ208582A (es)
PH (1) PH21108A (es)
PT (1) PT78760A (es)
ZA (1) ZA844604B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593994A (en) * 1994-09-29 1997-01-14 The Dupont Merck Pharmaceutical Company Prostaglandin synthase inhibitors
US5686470A (en) * 1995-02-10 1997-11-11 Weier; Richard M. 2, 3-substituted pyridines for the treatment of inflammation
DK0933346T3 (da) 1996-07-31 2004-03-29 Shionogi & Co Nye p-terphenylforbindelser
US6956132B2 (en) * 2001-08-03 2005-10-18 Ishihara Sangyo Kaisha. Ltd. Process for producing 2-phenylacetophenone derivatives and precursors therefor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1572204A1 (de) * 1965-07-20 1969-05-29 Merck Ag E Organische Szintillatoren
US4197306A (en) * 1977-06-30 1980-04-08 Uniroyal, Inc. Aryl-substituted thiazoles
US4153703A (en) * 1977-06-30 1979-05-08 Uniroyal, Inc. Method of controlling insects and acarids with certain aryl-substituted thiazoles
US4168315A (en) * 1977-09-28 1979-09-18 The Upjohn Company Dianisyl thiazole compound, compositions and method of antithrombotic treatment
EP0005219B1 (en) * 1978-04-24 1981-07-22 A/S Dumex (Dumex Ltd.) Arylimidazoles, their synthesis and pharmaceutical or veterinary preparations containing them
US4322428A (en) * 1980-04-02 1982-03-30 Eli Lilly And Company 2(4-Fluorophenyl)-4,5,-bis(4-methoxyphenyl)thiazole and method of use
US4330552A (en) * 1980-11-06 1982-05-18 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-2-arylthioimidazoles

Also Published As

Publication number Publication date
GR82376B (es) 1984-12-13
FI842477A (fi) 1984-12-23
ES533553A0 (es) 1985-10-16
ZA844604B (en) 1986-02-26
AU2973484A (en) 1985-01-03
KR870000199B1 (ko) 1987-02-16
DK300684D0 (da) 1984-06-20
IL72146A0 (en) 1984-10-31
FI842477A0 (fi) 1984-06-19
HU194528B (en) 1988-02-29
DE3462129D1 (de) 1987-02-26
AU566411B2 (en) 1987-10-22
GB2142024A (en) 1985-01-09
HUT36075A (en) 1985-08-28
PT78760A (en) 1984-07-01
ATE25072T1 (de) 1987-02-15
CA1246621A (en) 1988-12-13
KR850000380A (ko) 1985-02-27
US4495202A (en) 1985-01-22
NZ208582A (en) 1986-07-11
DK300684A (da) 1984-12-23
DD217799A5 (de) 1985-01-23
JPS6013730A (ja) 1985-01-24
GB8415820D0 (en) 1984-07-25
GB2142024B (en) 1986-12-10
PH21108A (en) 1987-07-16
EP0130045A1 (en) 1985-01-02
IL72146A (en) 1987-08-31
EP0130045B1 (en) 1987-01-21

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