ES8507098A1 - Procedimiento para la preparacion de l(-)carnitina en forma de cloridrato o en forma de su sal interna. - Google Patents
Procedimiento para la preparacion de l(-)carnitina en forma de cloridrato o en forma de su sal interna.Info
- Publication number
- ES8507098A1 ES8507098A1 ES537690A ES537690A ES8507098A1 ES 8507098 A1 ES8507098 A1 ES 8507098A1 ES 537690 A ES537690 A ES 537690A ES 537690 A ES537690 A ES 537690A ES 8507098 A1 ES8507098 A1 ES 8507098A1
- Authority
- ES
- Spain
- Prior art keywords
- carnitine
- preparation
- inner salt
- hydrochloride
- carnitine hydrochloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
- C07C227/42—Crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/34—Preparation of optical isomers by separation of optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE L(-)CARNITINA EN FORMA DE CLORHIDRATO O EN FORMA DE SU SAL INTERNA.COMPRENDE: A) TRATAR AL CLORHIDRATO DE DL-CARNITINA CON UN ALCOXIDO SODICO Y CON ACIDO DI-BENZOIL-D(-)TARTARICO, EN SOLUCION METANOLICA, PARA OBTENER UNA SOLUCION DE DIASTEROMEROS; B) ENFRIAR A LA SOLUCION DE DIASTOMEROS A UNA TEMPERATURA INFERIOR A C10JC, PARA CRISTALIZAR FRACCIONADAMENTE EL ISOMERO DI-BENZOIL-D-(-)TARTRATO DE L(-)CARNITINA; Y C) TRATAR AL ISOMERO DIBENZOIL-D-(-)TARTRATO DE L(-)CARNITINA CON CLORHIDRICO ANHIDRO EN UN MEDIO APROTICO COMO ACETONA, METILETILCETONA O ACETATO DE ETILO, PARA LIBERAR L(-)CARNITINA EN FORMA DE CLORHIDRATO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8323563A IT1212785B (it) | 1983-11-02 | 1983-11-02 | Procedimento industriale per la separazione della d.l. carnitina nei suoi isomeri ottici. |
IT49045/84A IT1199211B (it) | 1984-10-22 | 1984-10-22 | Procedimento per la preparazione di l(-)carnitina cloruro e di l(-)carnitina sale interno |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8507098A1 true ES8507098A1 (es) | 1985-09-16 |
ES537690A0 ES537690A0 (es) | 1985-09-16 |
Family
ID=26328398
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES537690A Granted ES537690A0 (es) | 1983-11-02 | 1984-11-02 | Procedimiento para la preparacion de l(-)carnitina en forma de cloridrato o en forma de su sal interna. |
Country Status (10)
Country | Link |
---|---|
US (1) | US4933490A (es) |
EP (1) | EP0141408B1 (es) |
KR (1) | KR870002000B1 (es) |
AU (1) | AU549565B2 (es) |
CA (1) | CA1230610A (es) |
DE (1) | DE3479495D1 (es) |
DK (1) | DK164739C (es) |
ES (1) | ES537690A0 (es) |
FI (1) | FI79833C (es) |
NO (1) | NO165339C (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6191160A (ja) * | 1984-10-09 | 1986-05-09 | Nisshin Flour Milling Co Ltd | L−カルニチンの製造法 |
IT1188176B (it) * | 1985-07-05 | 1988-01-07 | Bicresearch Spa | Sali della carnitina particolarmente idonei per uso orale |
US5248601A (en) * | 1986-03-14 | 1993-09-28 | Franco Francalanci | Process for preparing L(-)-carnitine chloride |
IT1289974B1 (it) * | 1997-02-25 | 1998-10-19 | Aldo Fassi | Procedimento per la produzione di sali stabili e non igroscopici di l(-)carnitina e di alcanoli l(-)-carnitine |
KR100255039B1 (ko) | 1997-07-28 | 2000-05-01 | 박영구 | L-카르니틴의제조방법 |
US6560512B1 (en) * | 2002-01-04 | 2003-05-06 | Machine Consciousness, Inc. | Relational robotic controller |
CN109096129B (zh) * | 2018-09-30 | 2021-04-27 | 东北制药集团股份有限公司 | 一种左旋肉碱酒石酸盐的制备方法 |
CN114181101A (zh) * | 2021-11-26 | 2022-03-15 | 开原亨泰营养科技有限公司 | 能够控制产品晶型的左旋肉碱酒石酸盐的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD93347A (es) * | ||||
US3096368A (en) * | 1958-07-30 | 1963-07-02 | Process for preparing hydrolysis products of gamma-dimethyl amin-beta-hydroxybutyroni | |
US3151149A (en) * | 1959-01-31 | 1964-09-29 | Berlin Chemie Veb | Production of pure d-and l-carnitinenitrile-chloride |
US3135788A (en) * | 1959-09-28 | 1964-06-02 | Nihon Zoki Seiyaku Kabushikika | Preparation of dl-carnitine hydrochloride from trimethylamine hydrochloride and epihalogenohydrin |
-
1984
- 1984-10-31 CA CA000466746A patent/CA1230610A/en not_active Expired
- 1984-10-31 AU AU34861/84A patent/AU549565B2/en not_active Ceased
- 1984-11-01 NO NO844349A patent/NO165339C/no unknown
- 1984-11-01 KR KR1019840006839A patent/KR870002000B1/ko not_active IP Right Cessation
- 1984-11-02 FI FI844314A patent/FI79833C/fi not_active IP Right Cessation
- 1984-11-02 ES ES537690A patent/ES537690A0/es active Granted
- 1984-11-02 DE DE8484113184T patent/DE3479495D1/de not_active Expired
- 1984-11-02 EP EP84113184A patent/EP0141408B1/en not_active Expired
- 1984-11-02 DK DK523084A patent/DK164739C/da not_active IP Right Cessation
-
1987
- 1987-09-22 US US07/099,633 patent/US4933490A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US4933490A (en) | 1990-06-12 |
DK164739B (da) | 1992-08-10 |
EP0141408B1 (en) | 1989-08-23 |
AU549565B2 (en) | 1986-01-30 |
DK523084A (da) | 1985-05-03 |
FI79833B (fi) | 1989-11-30 |
KR870002000B1 (ko) | 1987-11-30 |
KR850004099A (ko) | 1985-07-01 |
DK523084D0 (da) | 1984-11-02 |
NO165339C (no) | 1991-01-30 |
EP0141408A3 (en) | 1986-05-07 |
CA1230610A (en) | 1987-12-22 |
FI844314L (fi) | 1985-05-03 |
DK164739C (da) | 1992-12-28 |
EP0141408A2 (en) | 1985-05-15 |
DE3479495D1 (en) | 1989-09-28 |
AU3486184A (en) | 1985-05-09 |
NO844349L (no) | 1985-05-03 |
NO165339B (no) | 1990-10-22 |
FI844314A0 (fi) | 1984-11-02 |
ES537690A0 (es) | 1985-09-16 |
FI79833C (fi) | 1990-03-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB2148287B (en) | Preparation of aminocarboxylic acid salts from amino alcohols | |
EP0135846A3 (en) | Production of l-amino acids by transamination | |
ES8507098A1 (es) | Procedimiento para la preparacion de l(-)carnitina en forma de cloridrato o en forma de su sal interna. | |
PT73156B (en) | Process for preparing n-(cicloalquil)amino acid derivatives | |
AR240554A1 (es) | Procedimiento para preparar derivados del acido azulen-3-sulfonico y sus sales | |
DE3469360D1 (en) | Process for the preparation of an n-substituted carbamoyllactam compound | |
DE3263557D1 (en) | Process for the preparation of quinolinic acid | |
PT80376A (en) | Process for the preparation of herbicides containing dimethylphosphinoilacetic acid derivatives | |
ZA837379B (en) | Process for the preparation of benzoxazolyl-and benzothia-zolyloxyphenoxypropionic acid derivatives | |
GB2170198B (en) | Process for the preparation of glutamic acid or the monosodium salt thereof | |
FI894119A0 (fi) | Menetelmä isoseriini-N,N-dietikkahapon trinatriumsuolan valmistamiseksi | |
PT74322A (en) | Process for preparing fungicides n-acyl amino acid derivatives | |
DE3263947D1 (en) | Process for the preparation of p-nitrotoluene sulfonic acid | |
PT79823A (en) | Process for the preparation of n-(naphtyl-alquil)-hydroxilamines | |
DE3460280D1 (en) | Process for the preparation of n-methylhomoveratryl amine | |
DE3266154D1 (en) | Process for the preparation of n-substituted urethanes | |
DE3463264D1 (en) | Process for the preparation of 4-nitrotoluene-2-sulfonic acid | |
YU15385A (en) | Process for obtaining derivatives of n-substituted aminopropanesulphonic acid | |
DE3268091D1 (en) | Process for preparing beta-hydroxy amino acid | |
PT73634A (en) | Process for the preparation of 1-benzotriazolyloxi-acetic acid amides having herbicidal effect | |
GB2101133B (en) | Process for preparing the acid chloride of carnitine | |
DE3264763D1 (en) | Process for the preparation of aniline derivatives | |
DE3461082D1 (en) | Process for the preparation of 1-amino-4-bromo-anthraquinone-2-sulfonic acid | |
YU33881A (en) | Process for preparing n-substituted amides of alpha-amino acid | |
DE3361347D1 (en) | Process for the manufacture of dichlorolactic acid or the nitrile or the amide of dichlorolactic acid |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970612 |