DE3479495D1 - Process for the preparation of l(-)carnitine hydrochloride and of l(-)carnitine inner salt - Google Patents

Process for the preparation of l(-)carnitine hydrochloride and of l(-)carnitine inner salt

Info

Publication number
DE3479495D1
DE3479495D1 DE8484113184T DE3479495T DE3479495D1 DE 3479495 D1 DE3479495 D1 DE 3479495D1 DE 8484113184 T DE8484113184 T DE 8484113184T DE 3479495 T DE3479495 T DE 3479495T DE 3479495 D1 DE3479495 D1 DE 3479495D1
Authority
DE
Germany
Prior art keywords
carnitine
preparation
inner salt
hydrochloride
carnitine hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484113184T
Other languages
English (en)
Inventor
Vincenzo Iannella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierrel SpA
Original Assignee
ISOM SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT8323563A external-priority patent/IT1212785B/it
Priority claimed from IT49045/84A external-priority patent/IT1199211B/it
Application filed by ISOM SpA filed Critical ISOM SpA
Application granted granted Critical
Publication of DE3479495D1 publication Critical patent/DE3479495D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification
    • C07C227/42—Crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/34—Preparation of optical isomers by separation of optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8484113184T 1983-11-02 1984-11-02 Process for the preparation of l(-)carnitine hydrochloride and of l(-)carnitine inner salt Expired DE3479495D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8323563A IT1212785B (it) 1983-11-02 1983-11-02 Procedimento industriale per la separazione della d.l. carnitina nei suoi isomeri ottici.
IT49045/84A IT1199211B (it) 1984-10-22 1984-10-22 Procedimento per la preparazione di l(-)carnitina cloruro e di l(-)carnitina sale interno

Publications (1)

Publication Number Publication Date
DE3479495D1 true DE3479495D1 (en) 1989-09-28

Family

ID=26328398

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484113184T Expired DE3479495D1 (en) 1983-11-02 1984-11-02 Process for the preparation of l(-)carnitine hydrochloride and of l(-)carnitine inner salt

Country Status (10)

Country Link
US (1) US4933490A (de)
EP (1) EP0141408B1 (de)
KR (1) KR870002000B1 (de)
AU (1) AU549565B2 (de)
CA (1) CA1230610A (de)
DE (1) DE3479495D1 (de)
DK (1) DK164739C (de)
ES (1) ES537690A0 (de)
FI (1) FI79833C (de)
NO (1) NO165339C (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6191160A (ja) * 1984-10-09 1986-05-09 Nisshin Flour Milling Co Ltd Ｌ−カルニチンの製造法
IT1188176B (it) * 1985-07-05 1988-01-07 Bicresearch Spa Sali della carnitina particolarmente idonei per uso orale
US5248601A (en) * 1986-03-14 1993-09-28 Franco Francalanci Process for preparing L(-)-carnitine chloride
IT1289974B1 (it) * 1997-02-25 1998-10-19 Aldo Fassi Procedimento per la produzione di sali stabili e non igroscopici di l(-)carnitina e di alcanoli l(-)-carnitine
KR100255039B1 (ko) 1997-07-28 2000-05-01 박영구 L-카르니틴의제조방법
US6560512B1 (en) * 2002-01-04 2003-05-06 Machine Consciousness, Inc. Relational robotic controller
CN109096129B (zh) * 2018-09-30 2021-04-27 东北制药集团股份有限公司 一种左旋肉碱酒石酸盐的制备方法
CN114181101A (zh) * 2021-11-26 2022-03-15 开原亨泰营养科技有限公司 能够控制产品晶型的左旋肉碱酒石酸盐的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD93347A (de) *
US3096368A (en) * 1958-07-30 1963-07-02 Process for preparing hydrolysis products of gamma-dimethyl amin-beta-hydroxybutyroni
US3151149A (en) * 1959-01-31 1964-09-29 Berlin Chemie Veb Production of pure d-and l-carnitinenitrile-chloride
US3135788A (en) * 1959-09-28 1964-06-02 Nihon Zoki Seiyaku Kabushikika Preparation of dl-carnitine hydrochloride from trimethylamine hydrochloride and epihalogenohydrin

Also Published As

Publication number Publication date
KR870002000B1 (ko) 1987-11-30
ES8507098A1 (es) 1985-09-16
DK523084D0 (da) 1984-11-02
DK164739B (da) 1992-08-10
FI844314A0 (fi) 1984-11-02
NO844349L (no) 1985-05-03
CA1230610A (en) 1987-12-22
NO165339C (no) 1991-01-30
DK164739C (da) 1992-12-28
AU549565B2 (en) 1986-01-30
EP0141408A2 (de) 1985-05-15
FI844314L (fi) 1985-05-03
EP0141408B1 (de) 1989-08-23
AU3486184A (en) 1985-05-09
FI79833C (fi) 1990-03-12
EP0141408A3 (en) 1986-05-07
KR850004099A (ko) 1985-07-01
NO165339B (no) 1990-10-22
DK523084A (da) 1985-05-03
FI79833B (fi) 1989-11-30
ES537690A0 (es) 1985-09-16
US4933490A (en) 1990-06-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PIERREL S.P.A., CAPUA, IT

8328 Change in the person/name/address of the agent

Free format text: TUERK, D., DIPL.-CHEM. DR.RER.NAT. GILLE, C., DIPL.-ING. HRABAL, U., DIPL.-CHEM. DR.RER.NAT. LEIFERT, E., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 4000 DUESSELDORF

8339 Ceased/non-payment of the annual fee