ES8505968A1 - Procedimiento para preparar (6-(etil-(2-hidroxipropil)-amino)-3-piridazinil)-hidrazinocarboxilato de etilo - Google Patents

Procedimiento para preparar (6-(etil-(2-hidroxipropil)-amino)-3-piridazinil)-hidrazinocarboxilato de etilo

Info

Publication number
ES8505968A1
ES8505968A1 ES531544A ES531544A ES8505968A1 ES 8505968 A1 ES8505968 A1 ES 8505968A1 ES 531544 A ES531544 A ES 531544A ES 531544 A ES531544 A ES 531544A ES 8505968 A1 ES8505968 A1 ES 8505968A1
Authority
ES
Spain
Prior art keywords
ethyl
preparation
pharmaceutically active
hydroxypropyl
pyridazine derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES531544A
Other languages
English (en)
Other versions
ES531544A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ISF SpA
Original Assignee
ISF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ISF SpA filed Critical ISF SpA
Publication of ES531544A0 publication Critical patent/ES531544A0/es
Publication of ES8505968A1 publication Critical patent/ES8505968A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE I- ETIL-(2-HIDROXIPROPIL)-AMINO-3-PIRIDAZINILL-HIDRAZIONOCARBOXILATO DE ETILO.COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, LAS 3-CLORO-6-HIDRAZINOPIRIDAZINA, EN FORMA PROTEGIDA EN EL GRUPO HIDRAZINO, ES TRATADA CON UN AGENTE OXIDANTE; SEGUNDA, EL DERIVADO AZOICO CORRESPONDIENTE, OBTENIDO, SE TRATA CON ETIL-(2-HIDROXIPROPIL)-AMINA SALIFICADA; Y POR ULTIMO, LA RESULTANTE 3-ETIL-2(-HIDROXIPROPIL)-AMINO-6-(AZO PROTEGIDO)-PIRIDAZINA, ES REDUCIDA, DESPROTEGIDA Y LUEGO ACILADA.DE APLICACION EN MEDICINA POR SU ACTIVIDAD INTENSA Y DURADERA.
ES531544A 1983-04-28 1984-04-12 Procedimiento para preparar (6-(etil-(2-hidroxipropil)-amino)-3-piridazinil)-hidrazinocarboxilato de etilo Expired ES8505968A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8320813A IT1212734B (it) 1983-04-28 1983-04-28 Preparazione di un derivato piridazinico farmacologicamente attivo.

Publications (2)

Publication Number Publication Date
ES531544A0 ES531544A0 (es) 1985-06-16
ES8505968A1 true ES8505968A1 (es) 1985-06-16

Family

ID=11172430

Family Applications (1)

Application Number Title Priority Date Filing Date
ES531544A Expired ES8505968A1 (es) 1983-04-28 1984-04-12 Procedimiento para preparar (6-(etil-(2-hidroxipropil)-amino)-3-piridazinil)-hidrazinocarboxilato de etilo

Country Status (17)

Country Link
US (2) US4575552A (es)
EP (1) EP0124058A1 (es)
JP (2) JPS59206362A (es)
KR (1) KR910007241B1 (es)
AU (1) AU561504B2 (es)
CA (1) CA1212948A (es)
DK (1) DK211384A (es)
ES (1) ES8505968A1 (es)
FI (1) FI841637A (es)
GR (1) GR81992B (es)
IL (1) IL71588A (es)
IT (1) IT1212734B (es)
NO (1) NO841710L (es)
PH (1) PH19157A (es)
PT (1) PT78440B (es)
YU (1) YU44988B (es)
ZA (1) ZA842852B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1183615B (it) * 1985-05-13 1987-10-22 Isf Spa Processo per preparare derivati di 6-ammino-3idrazinopiridazina
CA1294616C (en) * 1986-06-17 1992-01-21 Noboru Sugishima Process for production of 1-aminoanthraquinone
US5082939A (en) * 1987-01-08 1992-01-21 I.S.F. Societa Per Azioni Pyridazine derivatives
IT1208003B (it) * 1987-01-08 1989-06-01 Isf Spa Procedimento per preparare derivati alcossi alchiliden, idrazino, piridazinici.
JPH0465754U (es) * 1990-10-17 1992-06-09
EP2370513A1 (en) * 2008-08-21 2011-10-05 Retilox Química Especial Ltda Oxygen resistant organic peroxides for reticulation/cure and their use in the process of continuous vulcanization in hot air tunnel

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642792A (en) * 1968-02-26 1972-02-15 Lepetit Spa Pyridazine derivatives
IT1054107B (it) * 1970-12-15 1981-11-10 Isf Spa Nuove 3,idrazinopiridazine 6,sostituite ad attivita antiiperten siva e loro preparazione
US4002753A (en) * 1973-03-07 1977-01-11 I.S.F. S.P.A. 6-Substituted 3-carbethoxyhydrazinopyridazines
GB1470747A (en) * 1976-02-19 1977-04-21 Isf Spa Pyridazine derivative
IT1063908B (it) * 1976-06-11 1985-02-18 Isf Spa Derivati idrazinopiridazinici

Also Published As

Publication number Publication date
ES531544A0 (es) 1985-06-16
IL71588A0 (en) 1984-07-31
IT1212734B (it) 1989-11-30
AU561504B2 (en) 1987-05-07
NO841710L (no) 1984-10-29
KR910007241B1 (ko) 1991-09-24
YU76584A (en) 1986-10-31
JPS63290866A (ja) 1988-11-28
JPS59206362A (ja) 1984-11-22
ZA842852B (en) 1986-10-29
US4632982A (en) 1986-12-30
JPH0513948B2 (es) 1993-02-23
DK211384D0 (da) 1984-04-27
GR81992B (es) 1984-12-12
DK211384A (da) 1984-10-29
YU44988B (en) 1991-06-30
FI841637A (fi) 1984-10-29
JPS6153347B2 (es) 1986-11-17
EP0124058A1 (en) 1984-11-07
PT78440A (en) 1984-05-01
AU2747184A (en) 1984-11-01
FI841637A0 (fi) 1984-04-26
CA1212948A (en) 1986-10-21
IT8320813A0 (it) 1983-04-28
PT78440B (en) 1986-05-27
US4575552A (en) 1986-03-11
IL71588A (en) 1987-09-16
PH19157A (en) 1986-01-15
KR840008331A (ko) 1984-12-14

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203