ES8505382A1 - Un procedimiento de preparacion de un derivado osido - Google Patents

Un procedimiento de preparacion de un derivado osido

Info

Publication number
ES8505382A1
ES8505382A1 ES534528A ES534528A ES8505382A1 ES 8505382 A1 ES8505382 A1 ES 8505382A1 ES 534528 A ES534528 A ES 534528A ES 534528 A ES534528 A ES 534528A ES 8505382 A1 ES8505382 A1 ES 8505382A1
Authority
ES
Spain
Prior art keywords
group
osides
radical
hydrolyzable
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES534528A
Other languages
English (en)
Other versions
ES534528A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SORI SOC RECH IND
Original Assignee
SORI SOC RECH IND
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SORI SOC RECH IND filed Critical SORI SOC RECH IND
Publication of ES8505382A1 publication Critical patent/ES8505382A1/es
Publication of ES534528A0 publication Critical patent/ES534528A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE BENCIL-FENIL-OSIDOS, DE FORMULA (I), Y SUS SALES DE ADICION DE ACIDOS, DONDE X1, X2, X3, X4 Y X5, IGUALES O DIFERENTES, REPRESENTAN HIDROGENO, HALOGENO, GRUPO ALQUILO, OH, ALCOXI O NITRO; Y R ES UN RADICAL OSO COMO EL ALFA-L-RAMNOSILO O MONOSACARIDOS NO HIDROLIZABLES.SE OBTIENEN POR REDUCCION DE COMPUESTOS DE FORMULA (II), DONDE Z ES CO O CHOH Y LOS DEMAS RADICALES SON LOS YA INDICADOS, MEDIANTE UN AGENTE REDUCTOR ESCOGIDO ENTRE NABH4 Y KBH4, EN ACIDO TRIFLUORACETICO.APLICABLES COMO SUSTANCIAS HIPOLESTEROLEMICAS E HIPOLIPIDEMICAS.
ES534528A 1983-07-20 1984-07-20 Un procedimiento de preparacion de un derivado osido Granted ES534528A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8311982A FR2549476B1 (fr) 1983-07-20 1983-07-20 Benzyl-phenyl-osides, procede de preparation et utilisation en therapeutique

Publications (2)

Publication Number Publication Date
ES8505382A1 true ES8505382A1 (es) 1985-05-16
ES534528A0 ES534528A0 (es) 1985-05-16

Family

ID=9290966

Family Applications (1)

Application Number Title Priority Date Filing Date
ES534528A Granted ES534528A0 (es) 1983-07-20 1984-07-20 Un procedimiento de preparacion de un derivado osido

Country Status (17)

Country Link
US (1) US4598068A (es)
EP (1) EP0133103B1 (es)
JP (1) JPS6041691A (es)
KR (1) KR910008109B1 (es)
AT (1) ATE30726T1 (es)
CA (1) CA1226576A (es)
CS (1) CS244692B2 (es)
DD (1) DD224596A5 (es)
DE (1) DE3467349D1 (es)
DK (1) DK164556C (es)
ES (1) ES534528A0 (es)
FR (1) FR2549476B1 (es)
GR (1) GR82068B (es)
HU (1) HU195835B (es)
NO (1) NO157259C (es)
PT (1) PT78938B (es)
ZA (1) ZA845580B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2614893B1 (fr) * 1987-05-04 1989-12-22 Fournier Innovation Synergie Nouveaux b-d-phenyl-thioxylosides, leur procede de preparation et leur application en therapeutique
US4960758A (en) * 1987-05-04 1990-10-02 Fournier Innovation Et Synergie Novel β-D-phenylthioxylosides, their method of preparation and their use as pharmaceuticals
FR2614894B1 (fr) * 1987-05-06 1989-06-16 Adir Nouvelles oximes derivees de la tylosine, leur procede de preparation et les compositions pharmaceutiques les contenant
US5246961A (en) * 1988-10-18 1993-09-21 Fournier Industrie Et Sante β-d-phenylthioxylosides, and their use as therapeutic agents
IE63544B1 (en) * 1988-10-18 1995-05-17 Fournier Ind & Sante Novel Beta-d-phenylthioxylosides their method of preparation and their use in therapy
ATE92074T1 (de) * 1988-11-03 1993-08-15 Fournier Ind & Sante Beta-d-phenylthioxyloside, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
FR2652353B1 (fr) * 1989-09-22 1994-02-11 Fournier Industrie Sante Nouveaux benzopyran-2-one-beta-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.
DK0421829T3 (da) * 1989-09-22 1995-01-16 Fournier Ind & Sante Nye benzopyranon-beta-D-thioxylosider, fremgangsmåde til deres fremstilling og deres terapeutiske anvendelse
US6291433B1 (en) 1999-06-11 2001-09-18 Fournier Industrie Et Sante Derivatives of α-D-Thioxyloside and their use against atheroma
SK287183B6 (sk) 2000-03-17 2010-02-08 Kissei Pharmaceutical Co., Ltd. Glukopyranozyloxybenzylbenzenový derivát, farmaceutická kompozícia s jeho obsahom, ich použitie a medziprodukt
PT1329456E (pt) * 2000-09-29 2006-12-29 Kissei Pharmaceutical Derivados de glucopiranosiloxibenzilbenzeno e composições medicinais que os contêm.
WO2002044192A1 (fr) * 2000-11-30 2002-06-06 Kissei Pharmaceutical Co., Ltd. Derives de glucopyranosyloxybenzylbenzene, compositions medicinales contenant ces derives et produits intermediaires obtenus lors de l'elaboration de ces compositions
TWI255817B (en) * 2001-02-14 2006-06-01 Kissei Pharmaceutical Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof
FR2826368B1 (fr) * 2001-06-21 2004-01-30 Fournier Lab Sa Nouveaux derives de [4-(4-cyanobenzoyl)phenyl] glycofuranoside, utilisation en tant que medicamment, procede d'obtention et compositions pharmaceutiques les contenant

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL167151C (nl) * 1971-04-09 1981-11-16 Acf Chemiefarma Nv Werkwijze ter bereiding van geneesmiddelen met anti-parasitaire werking op basis van halogeen bevatten- de 2,2'-methyleendifenolderivaten, alsmede werkwijze ter bereiding van deze geneeskrachtige verbindingen.
FR2492830A1 (fr) * 1980-10-29 1982-04-30 Sori Soc Rech Ind Nouveaux composes appartenant a la famille des benzoyl- et a-hydroxybenzyl-phenyl-osides, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
NO842916L (no) 1985-01-21
EP0133103A1 (fr) 1985-02-13
NO157259C (no) 1988-02-17
PT78938A (fr) 1984-08-01
ES534528A0 (es) 1985-05-16
DK164556C (da) 1992-12-07
EP0133103B1 (fr) 1987-11-11
DK353184A (da) 1985-01-21
CA1226576A (en) 1987-09-08
FR2549476A1 (fr) 1985-01-25
PT78938B (fr) 1986-06-02
HUT36133A (en) 1985-08-28
JPS6041691A (ja) 1985-03-05
DK353184D0 (da) 1984-07-19
US4598068A (en) 1986-07-01
CS244692B2 (en) 1986-08-14
NO157259B (no) 1987-11-09
DK164556B (da) 1992-07-13
HU195835B (en) 1988-07-28
ZA845580B (en) 1985-02-27
DE3467349D1 (en) 1987-12-17
ATE30726T1 (de) 1987-11-15
CS556884A2 (en) 1985-09-17
DD224596A5 (de) 1985-07-10
GR82068B (es) 1984-12-13
FR2549476B1 (fr) 1986-04-25
KR850001227A (ko) 1985-03-16
KR910008109B1 (ko) 1991-10-10

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401