ES8302019A1 - Procedimiento de preparacion de nuevos derivados de benzol-y &-hidroxibencilpenil-osidos. - Google Patents

Procedimiento de preparacion de nuevos derivados de benzol-y &-hidroxibencilpenil-osidos.

Info

Publication number
ES8302019A1
ES8302019A1 ES506660A ES506660A ES8302019A1 ES 8302019 A1 ES8302019 A1 ES 8302019A1 ES 506660 A ES506660 A ES 506660A ES 506660 A ES506660 A ES 506660A ES 8302019 A1 ES8302019 A1 ES 8302019A1
Authority
ES
Spain
Prior art keywords
group
carbon atoms
derivatives
benzoyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES506660A
Other languages
English (en)
Other versions
ES506660A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SORI SOC RECH IND
Original Assignee
SORI SOC RECH IND
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SORI SOC RECH IND filed Critical SORI SOC RECH IND
Publication of ES8302019A1 publication Critical patent/ES8302019A1/es
Publication of ES506660A0 publication Critical patent/ES506660A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE BENZOIL- Y <007>-HIDROXIBENCILFENIL-OXIDOS, DE FORMULA (I), Y DE SUS DIATEROISOMEROS CUANDO Z ES CHOH, DE FORMULA (I), EN LA QUE Z ES CO O CHOH; R ES UN RADICAL OXO; Y X -X PUEDEN SER VARIOS RADICALES. CONSISTE EN LA REACCION DE UN DERIVADO DE FENILFENOL DE FORMULA (II), EN LA QUE A ES HIDROGENO, SODIO O POTASIO, Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), CON UN DERIVADO OXO, TAL COMO HALOGENOACILOXOS O ACILOXOS. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE, A UNA TEMPERATURA ENTRE 0<025>C Y LA DE REFLUJO DEL MEDIO DE REACCION. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANTIULCEROSOS, ANTIAGREGANTES PLAQUETARIOS, ANTITROMBOTICOS Y OXIGENADORES CEREBRALES.
ES506660A 1980-10-29 1981-10-28 Procedimiento de preparacion de nuevos derivados de benzol-y &-hidroxibencilpenil-osidos. Granted ES506660A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8023133A FR2492830A1 (fr) 1980-10-29 1980-10-29 Nouveaux composes appartenant a la famille des benzoyl- et a-hydroxybenzyl-phenyl-osides, leur procede de preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
ES8302019A1 true ES8302019A1 (es) 1983-01-01
ES506660A0 ES506660A0 (es) 1983-01-01

Family

ID=9247461

Family Applications (1)

Application Number Title Priority Date Filing Date
ES506660A Granted ES506660A0 (es) 1980-10-29 1981-10-28 Procedimiento de preparacion de nuevos derivados de benzol-y &-hidroxibencilpenil-osidos.

Country Status (14)

Country Link
US (1) US4432973A (es)
EP (1) EP0051023B1 (es)
JP (1) JPS57102899A (es)
KR (1) KR870001926B1 (es)
AT (1) ATE7701T1 (es)
CA (1) CA1181745A (es)
CS (1) CS224629B2 (es)
DD (1) DD202157A5 (es)
DE (1) DE3163912D1 (es)
ES (1) ES506660A0 (es)
FR (1) FR2492830A1 (es)
GR (1) GR75759B (es)
HU (1) HU191341B (es)
ZA (1) ZA817314B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549476B1 (fr) * 1983-07-20 1986-04-25 Rech Ind Benzyl-phenyl-osides, procede de preparation et utilisation en therapeutique
JPS63215688A (ja) * 1987-03-04 1988-09-08 Jujo Paper Co Ltd フェノ−ル配糖体の製造法
FR2614893B1 (fr) * 1987-05-04 1989-12-22 Fournier Innovation Synergie Nouveaux b-d-phenyl-thioxylosides, leur procede de preparation et leur application en therapeutique
US4960758A (en) * 1987-05-04 1990-10-02 Fournier Innovation Et Synergie Novel β-D-phenylthioxylosides, their method of preparation and their use as pharmaceuticals
FR2614894B1 (fr) * 1987-05-06 1989-06-16 Adir Nouvelles oximes derivees de la tylosine, leur procede de preparation et les compositions pharmaceutiques les contenant
IE63544B1 (en) * 1988-10-18 1995-05-17 Fournier Ind & Sante Novel Beta-d-phenylthioxylosides their method of preparation and their use in therapy
ATE113956T1 (de) * 1989-09-22 1994-11-15 Fournier Ind & Sante Benzopyranon-beta-d-thioxyloside, verfahren zu ihrer herstellung und ihre therapeutische verwendung.
FR2652353B1 (fr) * 1989-09-22 1994-02-11 Fournier Industrie Sante Nouveaux benzopyran-2-one-beta-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.
ID26806A (id) * 1998-06-24 2001-02-08 Fournier Induatrie Et Sante SENYAWA BARU YANG BERASAL DARI a-D-SILOSA, METODA PEMBUATAN DAN PENGGUNAAN TERAPINYA
US6525094B1 (en) 1999-06-01 2003-02-25 The University Of Texas Southwestern Medical Center Method of treating hair loss using diphenylether derivatives
EP1185232A1 (en) 1999-06-01 2002-03-13 University Of Texas Southwestern Medical Center Method of treating hair loss using sulfonyl thyromimetic compounds
US6680344B1 (en) 1999-06-01 2004-01-20 The University Of Texas Southwestern Medical Center Method of treating hair loss using diphenylmethane derivatives
US6291433B1 (en) 1999-06-11 2001-09-18 Fournier Industrie Et Sante Derivatives of α-D-Thioxyloside and their use against atheroma
FR2802929B1 (fr) * 1999-12-23 2003-06-06 Fournier Ind & Sante Benzophenone alpha-d-glycopyranosides, preparation et utilisation en therapeutique
FR2802930B1 (fr) * 1999-12-23 2003-10-10 Fournier Ind & Sante Benzophenone glycopyranosides, preparation et utilisation en therapeutique
US6586434B2 (en) * 2000-03-10 2003-07-01 G.D. Searle, Llc Method for the preparation of tetrahydrobenzothiepines
FR2826367B1 (fr) * 2001-06-21 2004-01-30 Fournier Lab Sa Nouveaux derives de [4-(4-cyanobenzoyl)phenyl] glycopyranoside, utilisation en tant que medicamment, procede d'obtention et compositions pharmaceutiques les contenant
FR2826368B1 (fr) * 2001-06-21 2004-01-30 Fournier Lab Sa Nouveaux derives de [4-(4-cyanobenzoyl)phenyl] glycofuranoside, utilisation en tant que medicamment, procede d'obtention et compositions pharmaceutiques les contenant
FR2860234B1 (fr) 2003-09-25 2005-12-23 Fournier Lab Sa Nouveaux derives 666 du thioxylose
WO2005077382A1 (ja) * 2004-02-17 2005-08-25 National Institute Of Advanced Industrial Science And Technology プリオン増殖抑制剤
EP1911738A4 (en) * 2005-07-29 2009-12-16 Takeda Pharmaceutical PHENOXYALKANSÄUREVERBINDUNG
FR2903698B1 (fr) 2006-07-13 2009-01-30 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose.
FR2906247B1 (fr) * 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose
FR2906248B1 (fr) 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2218569A (en) * 1939-09-13 1940-10-22 Dow Chemical Co Glycosides of pentose ethers
US2798079A (en) * 1953-12-29 1957-07-02 Universal Oil Prod Co Condensation of aromatic hydrocarbon derivatives with carbohydrates and related materials
US3152115A (en) * 1960-11-17 1964-10-06 Geigy Chem Corp New aryl glucosaminides
US3356674A (en) * 1961-07-07 1967-12-05 Rikagaku Kenkyusho 3-c-hydroxymethyl-3, 5-didesoxy-l-lyxofuranose and its derivatives, and a process for the production thereof
US3496196A (en) * 1965-10-02 1970-02-17 Tanabe Pharm Co Ltd 4,6-diazido-4,6-dideoxy-myo-inositol tetraacylates
FR2141532B1 (es) * 1971-06-14 1974-08-23 Anvar
US3960835A (en) * 1974-01-18 1976-06-01 Commercial Solvents Corporation Zearaline glycoside compounds
US4175123A (en) * 1976-12-23 1979-11-20 Bayer Aktiengesellschaft Amino-sugar derivatives, process for their preparation and pharmaceutical composition thereof

Also Published As

Publication number Publication date
JPS57102899A (en) 1982-06-26
HU191341B (en) 1987-02-27
US4432973A (en) 1984-02-21
GR75759B (es) 1984-08-02
ATE7701T1 (de) 1984-06-15
CA1181745A (en) 1985-01-29
CS224629B2 (en) 1984-01-16
DD202157A5 (de) 1983-08-31
FR2492830B1 (es) 1983-10-07
KR870001926B1 (ko) 1987-10-22
EP0051023A1 (fr) 1982-05-05
KR830007485A (ko) 1983-10-21
EP0051023B1 (fr) 1984-05-30
ES506660A0 (es) 1983-01-01
ZA817314B (en) 1982-10-27
JPH024235B2 (es) 1990-01-26
FR2492830A1 (fr) 1982-04-30
DE3163912D1 (en) 1984-07-05

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303