ES8501411A1 - Un metodo para la preparacion de un derivado de aminoacido. - Google Patents
Un metodo para la preparacion de un derivado de aminoacido.Info
- Publication number
- ES8501411A1 ES8501411A1 ES524284A ES524284A ES8501411A1 ES 8501411 A1 ES8501411 A1 ES 8501411A1 ES 524284 A ES524284 A ES 524284A ES 524284 A ES524284 A ES 524284A ES 8501411 A1 ES8501411 A1 ES 8501411A1
- Authority
- ES
- Spain
- Prior art keywords
- amino acid
- acid derivatives
- drugs containing
- antihypertensive drugs
- tripeptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/80—Antihypertensive peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
METODO PARA LA PREPARACION DE UN DERIVADO DE AMINOACIDO.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) O UN DERIVADO REACTIVO DEL MISMO CON UN COMPUESTO DE FORMULA (III) O SAL DEL MISMO, PARA OBTENER UN COMPUESTO DE FORMULA (I). DONDE R1 Y R2 SIGNIFICA HIDROXILO, ALCOHILOXI, ARILOXI, ARALCOHILOXI, ALCOHILO, ARILO O ARALCOHILO; R3, R5, R8 Y R11 SIGNIFICAN HIDROGENO O ALCOHILO; R4, R7 Y R10 SIGNIFICAN HIDROGENO, ALCOHILO, ARILO O ARALCOHILO SUSTITUIDO O INSUSTITUIDO; R6 Y R9 SIGNIFICAN HIDROGENO, ALCOHILO, ARILO O ARALCOHILO; R12 SIGNIFICA HIDROXILO, ALCOHILOXI, ARILOXI, ARALCOHILOXI, AMINO, MONO O DI ALCOHIL, O ARALCOHILAMINO.ESTE PRODUCTO ES UTIL COMO FARMACO ANTIHIPERTENSIVO Y COMO UN COMPUESTO INETEMERIO PARA SU PRODUCCION.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP57009341A JPS58126896A (ja) | 1982-01-23 | 1982-01-23 | アラニルプロリン誘導体およびこれを含有する降圧剤 |
JP57141831A JPS5931788A (ja) | 1982-08-16 | 1982-08-16 | アミノ酸誘導体およびこれを含有する降圧剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8501411A1 true ES8501411A1 (es) | 1984-11-16 |
ES524284A0 ES524284A0 (es) | 1984-11-16 |
Family
ID=26344046
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES519168A Expired ES8403138A1 (es) | 1982-01-23 | 1983-01-21 | Un metodo para la preparacion de un derivado de aminoacido. |
ES524284A Granted ES524284A0 (es) | 1982-01-23 | 1983-07-20 | Un metodo para la preparacion de un derivado de aminoacido. |
ES524285A Expired ES8501412A1 (es) | 1982-01-23 | 1983-07-20 | "un metodo para la preparacion de un derivado de aminoacido" |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES519168A Expired ES8403138A1 (es) | 1982-01-23 | 1983-01-21 | Un metodo para la preparacion de un derivado de aminoacido. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES524285A Expired ES8501412A1 (es) | 1982-01-23 | 1983-07-20 | "un metodo para la preparacion de un derivado de aminoacido" |
Country Status (4)
Country | Link |
---|---|
US (3) | US4472381A (es) |
EP (1) | EP0085488B1 (es) |
DE (1) | DE3381378D1 (es) |
ES (3) | ES8403138A1 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4595675A (en) * | 1979-09-19 | 1986-06-17 | Hoechst Aktiengesellschaft | Bicyclic α-iminocarboxylic acid compounds having hypotensive activity |
EP0085488B1 (en) * | 1982-01-23 | 1990-03-28 | Ajinomoto Co., Inc. | Amino acid derivatives and antihypertensive drugs containing them |
JPS60193994A (ja) * | 1984-03-13 | 1985-10-02 | Ajinomoto Co Inc | Ν−ホスフイノイル化方法 |
JPH0655758B2 (ja) * | 1984-08-24 | 1994-07-27 | 味の素株式会社 | アミノ酸誘導体 |
AU595309B2 (en) * | 1986-05-09 | 1990-03-29 | Dainippon Pharmaceutical Co. Ltd. | Tripeptide derivatives |
EP0376040A3 (en) * | 1988-12-27 | 1990-09-12 | American Cyanamid Company | N-phosphinyl di-and tripeptides as renin inhibitors |
FR2654430B1 (fr) * | 1989-11-15 | 1995-01-06 | Commissariat Energie Atomique | Nouveaux derives de peptides, utilisables comme inhibiteurs des collagenases bacteriennes. |
US5811387A (en) * | 1990-05-15 | 1998-09-22 | Chiron Corporation | Peptoid mixtures |
IE66205B1 (en) * | 1990-06-14 | 1995-12-13 | Paul A Bartlett | Polypeptide analogs |
US5189023A (en) * | 1990-09-04 | 1993-02-23 | American Cyanamid Company | Renin inhibitors |
FR2689764B1 (fr) * | 1992-04-10 | 1995-05-12 | Commissariat Energie Atomique | Utilisation de dérivés de peptides pour la fabrication de médicaments inhibiteurs des endopeptidases 24.15 et 24.16. |
WO2009037416A1 (en) * | 2007-09-20 | 2009-03-26 | Npil Pharmaceuticals (Uk) Limited | Process for preparing sulphonamides |
US9040046B2 (en) | 2011-01-31 | 2015-05-26 | Kai Xu | Sodium pump antibody agonists and methods of treating heart disease using the same |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4316896A (en) * | 1978-09-07 | 1982-02-23 | Merck & Co., Inc. | Aminoacid derivatives as antihypertensives |
EP0026867A1 (de) * | 1979-09-28 | 1981-04-15 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Peptidylphosphonsäuren, deren Herstellung und Verwendung und sie enthaltende pharmazeutische Präparate |
US4379146A (en) * | 1981-02-17 | 1983-04-05 | Merck & Co., Inc. | Substituted phosphonamides as antihypertensives |
US4466913A (en) * | 1981-06-30 | 1984-08-21 | Maiji Seika Kaisha Ltd. | Phosphorus-containing compounds and process for producing the same |
US4432971A (en) * | 1981-08-03 | 1984-02-21 | E. R. Squibb & Sons, Inc. | Phosphonamidate compounds |
US4432972A (en) * | 1981-08-03 | 1984-02-21 | E. R. Squibb & Sons, Inc. | Phosphonamidate compounds |
EP0085488B1 (en) * | 1982-01-23 | 1990-03-28 | Ajinomoto Co., Inc. | Amino acid derivatives and antihypertensive drugs containing them |
-
1983
- 1983-01-12 EP EP83300146A patent/EP0085488B1/en not_active Expired
- 1983-01-12 DE DE8383300146T patent/DE3381378D1/de not_active Expired - Lifetime
- 1983-01-18 US US06/458,844 patent/US4472381A/en not_active Expired - Fee Related
- 1983-01-21 ES ES519168A patent/ES8403138A1/es not_active Expired
- 1983-07-14 US US06/513,738 patent/US4536395A/en not_active Expired - Fee Related
- 1983-07-20 ES ES524284A patent/ES524284A0/es active Granted
- 1983-07-20 ES ES524285A patent/ES8501412A1/es not_active Expired
-
1984
- 1984-03-16 US US06/590,428 patent/US4590178A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US4590178A (en) | 1986-05-20 |
ES519168A0 (es) | 1984-03-01 |
EP0085488A3 (en) | 1985-12-27 |
DE3381378D1 (de) | 1990-05-03 |
ES8403138A1 (es) | 1984-03-01 |
ES524285A0 (es) | 1984-11-16 |
EP0085488B1 (en) | 1990-03-28 |
US4536395A (en) | 1985-08-20 |
US4472381A (en) | 1984-09-18 |
EP0085488A2 (en) | 1983-08-10 |
ES8501412A1 (es) | 1984-11-16 |
ES524284A0 (es) | 1984-11-16 |
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