ES8500990A1 - Un procedimiento de separar un componente de proteina plasmatica de su mezcla en un sistema de cultivo de celulas. - Google Patents

Un procedimiento de separar un componente de proteina plasmatica de su mezcla en un sistema de cultivo de celulas.

Info

Publication number
ES8500990A1
ES8500990A1 ES524150A ES524150A ES8500990A1 ES 8500990 A1 ES8500990 A1 ES 8500990A1 ES 524150 A ES524150 A ES 524150A ES 524150 A ES524150 A ES 524150A ES 8500990 A1 ES8500990 A1 ES 8500990A1
Authority
ES
Spain
Prior art keywords
cell culture
plasma proteins
culture systems
separation
cell cultures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524150A
Other languages
English (en)
Other versions
ES524150A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of ES8500990A1 publication Critical patent/ES8500990A1/es
Publication of ES524150A0 publication Critical patent/ES524150A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/823Lower fungi, e.g. mold
    • Y10S530/824Yeasts
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/825Bacteria
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/829Blood
    • Y10S530/83Plasma; serum
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/843Digestive system
    • Y10S530/846Liver

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

METODO DE SEPARACION DE COMPONENTES DE PROTEINA PLASMATICA DE SUS MEZCLAS EN SISTEMAS DE CULTIVO DE CELULAS.CONSISTE EN ABSORBER EL COMPONENTE DE PROTEINA PLASMATICA POR CONTACTO CON UN COPOLIMERO POLIELECTROLITICO RETICULADO, INSOLUBLE EN AGUA, DE UN MONOMERO NO SATURADO OLEFINICAMENTE C2-4 Y ACIDO O ANHIDRIDO POLICARBOXILICO NO SATURADO EN BAB, BBB DE 4 A 6 ATOMOS DE CARBONO CON GRUPOS COLGANTES FUNCIONALES DI-ALCOHIL INFERIOR-AMINO-ALCOHIL INFERIOR-IMIDO.TIENE APLICACIONES PARA LA SEPARACION DE UNA PROTEIAN DE COAGULACION DE SANGRE, A PARTIR DE SISTEMAS DE CULTIVO DE CELULAS BACTERIANAS, DE LEVADURAS Y HEPATICAS.
ES524150A 1982-07-19 1983-07-15 Un procedimiento de separar un componente de proteina plasmatica de su mezcla en un sistema de cultivo de celulas. Granted ES524150A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/399,604 US4382028A (en) 1982-07-19 1982-07-19 Separation of plasma proteins from cell culture systems

Publications (2)

Publication Number Publication Date
ES8500990A1 true ES8500990A1 (es) 1984-11-01
ES524150A0 ES524150A0 (es) 1984-11-01

Family

ID=23580190

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524150A Granted ES524150A0 (es) 1982-07-19 1983-07-15 Un procedimiento de separar un componente de proteina plasmatica de su mezcla en un sistema de cultivo de celulas.

Country Status (11)

Country Link
US (1) US4382028A (es)
EP (1) EP0099871B1 (es)
JP (1) JPS5928492A (es)
AT (1) ATE24934T1 (es)
AU (1) AU552859B2 (es)
CA (1) CA1202566A (es)
DE (1) DE3369159D1 (es)
ES (1) ES524150A0 (es)
HU (1) HU196832B (es)
IL (1) IL69272A (es)
ZA (1) ZA835181B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4517294A (en) * 1982-03-03 1985-05-14 Genentech, Inc. Human antithrombin III
US4632981A (en) * 1982-07-30 1986-12-30 Genentech, Inc. Human antithrombin III
US4533496A (en) * 1984-05-08 1985-08-06 Monsanto Company Method of isolating monoclonal antibodies from hybridoma cultures
US4554337A (en) * 1985-01-18 1985-11-19 Ralston Purina Company Modified protein adhesive binder and process for producing
US4775624A (en) * 1985-02-08 1988-10-04 Eli Lilly And Company Vectors and compounds for expression of human protein C
FR2579224B1 (fr) * 1985-03-25 1987-05-22 Genetica Procede de preparation microbiologique de la serum-albumine humaine
US4780529A (en) * 1985-08-09 1988-10-25 Biotech Research Laboratories, Inc. Isolation of an endotoxin inactivator from human plasma, and methods of use
US4677194A (en) * 1985-08-09 1987-06-30 Biotech Research Laboratories, Inc. Isolation of an endotoxin inactivator from human plasma
US5658790A (en) * 1986-09-04 1997-08-19 Bio 101, Inc. Cell culture media formulated in unit dose
US5118796A (en) * 1987-12-09 1992-06-02 Centocor, Incorporated Efficient large-scale purification of immunoglobulins and derivatives
EP0482088B1 (en) * 1989-07-20 1999-03-31 Analytical Control Systems, Inc. Improved stable coagulation controls
US5939325A (en) * 1989-07-20 1999-08-17 Analytical Control Systems, Inc. Stable whole blood coagulation controls
DE69023773T2 (de) * 1989-07-31 1996-10-24 Inst Belka Akad Nauk Sssr Verfahren zur herstellung von polypeptiden in einem zellfreien translationssystem.
US5659017A (en) * 1995-11-07 1997-08-19 Alpha Therapeutic Corporation Anion exchange process for the purification of Factor VIII
US6307013B1 (en) 1998-07-21 2001-10-23 Monsanto Technology Llc Clarification of protein precipitate suspensions using anionic polymeric flocculants
AUPR638801A0 (en) * 2001-07-13 2001-08-09 Life Therapeutics Limited Factor viii separation
US20060257958A1 (en) * 2005-05-13 2006-11-16 Pronucleotein Biotechnologies, Llc Magnetically-assisted test strip cartridge and method for using same
FR2902799B1 (fr) 2006-06-27 2012-10-26 Millipore Corp Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
US8362217B2 (en) 2006-12-21 2013-01-29 Emd Millipore Corporation Purification of proteins
US8569464B2 (en) 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
US8163886B2 (en) * 2006-12-21 2012-04-24 Emd Millipore Corporation Purification of proteins
WO2009151514A1 (en) * 2008-06-11 2009-12-17 Millipore Corporation Stirred tank bioreactor
CN105037535A (zh) 2008-12-16 2015-11-11 Emd密理博公司 搅拌槽反应器及方法
EP3597671B1 (en) 2010-05-17 2022-09-21 EMD Millipore Corporation Stimulus responsive polymers for the purification of biomolecules
CN113025684A (zh) * 2019-12-25 2021-06-25 深圳市帝迈生物技术有限公司 活化部分凝血活酶时间检测试剂以及试剂盒

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3554985A (en) * 1963-01-02 1971-01-12 Monsanto Co Cross-linked copolymer polyelectrolytes based on alpha,beta-ethylenically unsaturated acids
US3555001A (en) * 1969-05-29 1971-01-12 Monsanto Co Process for the fractionation of plasma and serum using water-insoluble polyelectrolytes containing diloweralkylaminoloweralkylimide groups
DD139949A3 (de) * 1974-10-23 1980-01-30 Luebbert Gustav Adolf Verfahren zur abtrennung von mikroorganismen
CA1101332A (fr) * 1976-01-30 1981-05-19 Edward Shanbrom Procedes simplifies pour la preparation de concentres de facteur viii de tres grande purete
NL7708005A (nl) * 1976-07-22 1978-01-24 Monsanto Co Werkwijze voor de bereiding van serumalbumine.
ES471858A1 (es) * 1977-07-25 1979-02-01 Monsanto Co Un metodo para separar el factor especifico de coagulacion de la sangre de una mezcla con otras proteinas de la sangre en un medio fluido
US4081432A (en) * 1977-07-25 1978-03-28 Monsanto Company Method of separating a Factor IX preparation from plasma using ethylene-maleic anhydride polymers

Also Published As

Publication number Publication date
AU552859B2 (en) 1986-06-26
US4382028A (en) 1983-05-03
ZA835181B (en) 1984-06-27
IL69272A (en) 1988-02-29
JPH0443638B2 (es) 1992-07-17
EP0099871A1 (en) 1984-02-01
DE3369159D1 (en) 1987-02-19
IL69272A0 (en) 1983-11-30
HU196832B (en) 1989-01-30
JPS5928492A (ja) 1984-02-15
CA1202566A (en) 1986-04-01
AU1693283A (en) 1984-01-26
EP0099871B1 (en) 1987-01-14
ATE24934T1 (de) 1987-01-15
ES524150A0 (es) 1984-11-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519