ATE130633T1 - Verfahren zur herstellung von polypeptiden in einem zellfreien translationssystem. - Google Patents
Verfahren zur herstellung von polypeptiden in einem zellfreien translationssystem.Info
- Publication number
- ATE130633T1 ATE130633T1 AT90912889T AT90912889T ATE130633T1 AT E130633 T1 ATE130633 T1 AT E130633T1 AT 90912889 T AT90912889 T AT 90912889T AT 90912889 T AT90912889 T AT 90912889T AT E130633 T1 ATE130633 T1 AT E130633T1
- Authority
- AT
- Austria
- Prior art keywords
- substrates
- translation system
- cell
- translation
- gtp
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000758 substrate Substances 0.000 abstract 4
- 150000001413 amino acids Chemical class 0.000 abstract 3
- 239000011159 matrix material Substances 0.000 abstract 2
- 210000003705 ribosome Anatomy 0.000 abstract 2
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 abstract 1
- 235000011180 diphosphates Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003094 microcapsule Substances 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 229920000867 polyelectrolyte Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/585—Calcitonins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/18011—Details ssRNA Bacteriophages positive-sense
- C12N2795/18111—Leviviridae
- C12N2795/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU4717700 | 1989-07-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE130633T1 true ATE130633T1 (de) | 1995-12-15 |
Family
ID=21460267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90912889T ATE130633T1 (de) | 1989-07-31 | 1990-06-05 | Verfahren zur herstellung von polypeptiden in einem zellfreien translationssystem. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0485608B1 (de) |
| JP (1) | JP2891540B2 (de) |
| AT (1) | ATE130633T1 (de) |
| CA (1) | CA2064685C (de) |
| DE (1) | DE69023773T2 (de) |
| WO (1) | WO1991002075A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994006928A1 (en) * | 1992-09-24 | 1994-03-31 | The Public Health Research Institute Of The City Of New York, Inc. | Coupled replication-translation methods and kits for protein synthesis |
| RU2169154C2 (ru) | 1999-03-25 | 2001-06-20 | Институт белка РАН | Способ получения полипептидов в бесклеточной системе |
| KR100749053B1 (ko) * | 2000-08-29 | 2007-08-13 | 셀프리 사이언스 코 엘티디 | 무세포 단백질 합성방법 |
| JP4762481B2 (ja) | 2000-08-30 | 2011-08-31 | 株式会社セルフリーサイエンス | 無細胞タンパク質合成用転写鋳型の設計および構築、並びにこれを用いる希釈バッチ方式コムギ胚芽無細胞タンパク質合成法 |
| CA2483332A1 (en) * | 2002-01-31 | 2003-08-07 | Yaeta Endo | Cell extract for cell-free protein synthesis and process for producing the same |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4382028A (en) * | 1982-07-19 | 1983-05-03 | Monsanto Company | Separation of plasma proteins from cell culture systems |
| SU1618761A1 (ru) * | 1987-04-29 | 1991-01-07 | Институт Белка Ан Ссср | Способ получени пептидов и белков в бесклеточной системе трансл ции |
-
1990
- 1990-06-05 CA CA002064685A patent/CA2064685C/en not_active Expired - Lifetime
- 1990-06-05 JP JP2512062A patent/JP2891540B2/ja not_active Expired - Lifetime
- 1990-06-05 AT AT90912889T patent/ATE130633T1/de not_active IP Right Cessation
- 1990-06-05 WO PCT/SU1990/000145 patent/WO1991002075A1/ru not_active Ceased
- 1990-06-05 DE DE69023773T patent/DE69023773T2/de not_active Expired - Lifetime
- 1990-06-05 EP EP90912889A patent/EP0485608B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69023773D1 (de) | 1996-01-04 |
| EP0485608B1 (de) | 1995-11-22 |
| DE69023773T2 (de) | 1996-10-24 |
| EP0485608A4 (en) | 1992-06-17 |
| JP2891540B2 (ja) | 1999-05-17 |
| CA2064685A1 (en) | 1991-02-01 |
| EP0485608A1 (de) | 1992-05-20 |
| CA2064685C (en) | 1996-06-18 |
| JPH05505095A (ja) | 1993-08-05 |
| WO1991002075A1 (en) | 1991-02-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |