KR900702009A - 인체 a형 모노아민 옥시다제를 코오딩 하는 dna - Google Patents

인체 a형 모노아민 옥시다제를 코오딩 하는 dna

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Publication number
KR900702009A
KR900702009A KR1019900700467A KR900700467A KR900702009A KR 900702009 A KR900702009 A KR 900702009A KR 1019900700467 A KR1019900700467 A KR 1019900700467A KR 900700467 A KR900700467 A KR 900700467A KR 900702009 A KR900702009 A KR 900702009A
Authority
KR
South Korea
Prior art keywords
cell
dna
vector
monoamine oxidase
encoding human
Prior art date
Application number
KR1019900700467A
Other languages
English (en)
Inventor
브레이크필드 크산드라
슈 윤-평
Original Assignee
브레이크필드 크산드라
슈 윤-평
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 브레이크필드 크산드라, 슈 윤-평 filed Critical 브레이크필드 크산드라
Publication of KR900702009A publication Critical patent/KR900702009A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

내용 없음

Description

인체 A형 모노아민 옥시다제를 코오딩 하는 DNA
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
도면 제1도는 합성 47-mer탐됨을 제조하는데 사용하기 위한, 추출된 DNA서열을 갖는 펩티드를 나타내며, 도면 제2도는 인체 MAO-A cDNA, HN 11의 완전한 튜클레오티드 서열 및 상응하는 아미노산 서열을 나타낸다.

Claims (12)

  1. 인체 A형 모노아민 옥시다제를 코오딩 하는 정제 DNA.
  2. 제1항에 있어서,상기 DNA가 게놈 DNA로부터 유래된 것임으로 특징으로 하는 정제 DNA.
  3. 제1항에 있어서, 상기 DNA가 cDNA로부터 유래된 것임을 특징으로 하는 정제 DNA.
  4. 인체 A형 모노아민 옥시다제를 코오딩하는 DNA를 포함하는 벡타.
  5. 제4항에 있어서, 상기 DNA가 프로모터와 시그날 펩티드를 코오딩하는 서열을 포함하는 조절 DNA에 의해 조절되는 벡타.
  6. 제5항에서 정의한 벡타로 형질전환시킨 세포
  7. 제6항에 있어서, 상기 세포가 세균 세포인 것을 특징으로 하는 세포.
  8. 제6항에 있어서, 상기 세포가 포유류 세포인 것을 특징으로 하는 세포.
  9. 제6항에 있어서, 상기 세포가 이스트 세포인 것을 특징으로 하는 세포.
  10. 제7항에, 제8항 또는 제9항에서 정의한 세포를 준비하고, 상기 세포를 배양배지중에서 배양한 후, 상기 배양된 세포 또는 상기 배지로부터 인체 재조합 MAO-A를 분리하는 것으로 구성되는 인체 제조합 MAO-A의 제조방법.
  11. 제4항에서 정의한 벡타(ATCC수탁번호 (미지정))로 형질전환시킨 세균세포.
  12. 제4항에서 정의한 벡타(ATCC수탁번호 (미지정))로 형질전환시킨 세균세포.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900700467A 1988-06-30 1989-06-29 인체 a형 모노아민 옥시다제를 코오딩 하는 dna KR900702009A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/213,544 US5030570A (en) 1988-06-30 1988-06-30 DNA encoding and method of expressing human monoamine oxidase type A
US213,544 1988-06-30
PCT/US1989/002901 WO1990000195A1 (en) 1988-06-30 1989-06-29 Dna encoding human monoamine oxidase type a

Publications (1)

Publication Number Publication Date
KR900702009A true KR900702009A (ko) 1990-12-05

Family

ID=22795509

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900700467A KR900702009A (ko) 1988-06-30 1989-06-29 인체 a형 모노아민 옥시다제를 코오딩 하는 dna

Country Status (10)

Country Link
US (1) US5030570A (ko)
EP (1) EP0424459A4 (ko)
JP (1) JPH04501505A (ko)
KR (1) KR900702009A (ko)
AU (1) AU630881B2 (ko)
CA (1) CA1335359C (ko)
DK (1) DK306990A (ko)
FI (1) FI906443A0 (ko)
HU (2) HUT61046A (ko)
WO (1) WO1990000195A1 (ko)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2087019A1 (en) 1990-07-10 1992-01-11 Richard L. Weinshank Nucleic acid sequences encoding a human dopamine d1 receptor
AU2492192A (en) * 1991-09-20 1993-04-27 General Hospital Corporation, The Diagnosis and therapy for parkinson's disease
US5856928A (en) * 1992-03-13 1999-01-05 Yan; Johnson F. Gene and protein representation, characterization and interpretation process
US5783680A (en) * 1993-10-06 1998-07-21 The General Hospital Corporation Genetic diagnosis and treatment for impulsive aggression
US6069229A (en) 1997-03-07 2000-05-30 Schering Corporation Mammalian proteinases; oxidoreductases; related reagents
DE69821919T2 (de) * 1997-05-23 2004-07-29 Tensei Suisan Co., Ltd., Karatsu Fischprotein, dessen gen, reagenzien zur induktion von apoptose, und antikrebsmittel
WO2001090318A2 (en) * 2000-05-26 2001-11-29 Bayer Aktiengesellschaft Regulation of human polyamine oxidase-like enzyme
GB0013810D0 (en) 2000-06-06 2000-07-26 Celltech Chiroscience Ltd Biological products
WO2002012460A2 (en) * 2000-08-04 2002-02-14 Bayer Aktiengesellschaft Isolation of a human amine oxidase-like protein
ATE518885T1 (de) 2002-05-28 2011-08-15 Ucb Pharma Sa Peg-positionsisomer von einem antikorper gegen tnfalpha (cdp870)
GB201000588D0 (en) 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial host strain
EP2380909A1 (en) 2010-04-26 2011-10-26 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. PTK-7 protein involved in breast cancer
GB201012599D0 (en) 2010-07-27 2010-09-08 Ucb Pharma Sa Process for purifying proteins
EP2546267A1 (en) 2011-07-13 2013-01-16 UCB Pharma S.A. Bacterial host strain expressing recombinant DsbC

Also Published As

Publication number Publication date
FI906443A0 (fi) 1990-12-28
DK306990A (da) 1991-02-25
AU3979989A (en) 1990-01-23
HUT61046A (en) 1992-11-30
JPH04501505A (ja) 1992-03-19
WO1990000195A1 (en) 1990-01-11
US5030570A (en) 1991-07-09
DK306990D0 (da) 1990-12-28
EP0424459A1 (en) 1991-05-02
HU214412B (hu) 1998-03-30
AU630881B2 (en) 1992-11-12
CA1335359C (en) 1995-04-25
EP0424459A4 (en) 1991-10-30

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