ES8500939A1 - Procedimiento para la obtencion de derivados de la amino-5 ditiol-1, 2 ona-3 - Google Patents

Procedimiento para la obtencion de derivados de la amino-5 ditiol-1, 2 ona-3

Info

Publication number
ES8500939A1
ES8500939A1 ES529986A ES529986A ES8500939A1 ES 8500939 A1 ES8500939 A1 ES 8500939A1 ES 529986 A ES529986 A ES 529986A ES 529986 A ES529986 A ES 529986A ES 8500939 A1 ES8500939 A1 ES 8500939A1
Authority
ES
Spain
Prior art keywords
amino
substituted
alkyl
dialkylcarbamoyl
alkylcarbamoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES529986A
Other languages
English (en)
Other versions
ES529986A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Publication of ES8500939A1 publication Critical patent/ES8500939A1/es
Publication of ES529986A0 publication Critical patent/ES529986A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE LA AMINO-5-DITIOL-1,2-ONA-3, DE SUS SALES METALICAS Y DE ADICION CON ACIDOS Y BASES NITROGENADAS, DE FORMULA (I), EN LA QUE R ES HIDROGENO O CLORO; Y R1 Y R2 PUEDEN SER VARIOS RADICALES.CONSISTE EN LA REACCION DE UNA AMINA DE FORMULA R1NHR2, EN LA QUE R1 Y R2 SON LOS MISMOS QUE EN LA FORMULA (I), CON DICLORO-4,5-DITIOL-1,2-ONA-3; SEGUIDA DE LA SEPARACION DEL PRODUCTO FORMADO Y EVENTUAL DESCLORACION POR TRATAMIENTO CON UN HIDRURO DE TRIALQUILESTAN/O.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA ENFERMEDAD REUMATICA.
ES529986A 1983-02-24 1984-02-23 Procedimiento para la obtencion de derivados de la amino-5 ditiol-1, 2 ona-3 Granted ES529986A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8303005A FR2541680B1 (fr) 1983-02-24 1983-02-24 Nouveaux derives de l'amino-5 dithiole-1,2 one-3, leur preparation et les compositions medicinales qui les contiennent

Publications (2)

Publication Number Publication Date
ES8500939A1 true ES8500939A1 (es) 1984-11-01
ES529986A0 ES529986A0 (es) 1984-11-01

Family

ID=9286218

Family Applications (1)

Application Number Title Priority Date Filing Date
ES529986A Granted ES529986A0 (es) 1983-02-24 1984-02-23 Procedimiento para la obtencion de derivados de la amino-5 ditiol-1, 2 ona-3

Country Status (18)

Country Link
US (1) US4576954A (es)
EP (1) EP0119896B1 (es)
JP (1) JPS59163383A (es)
KR (1) KR900006745B1 (es)
AT (1) ATE22690T1 (es)
AU (1) AU567718B2 (es)
CA (1) CA1227197A (es)
DE (1) DE3460896D1 (es)
DK (1) DK159111C (es)
ES (1) ES529986A0 (es)
FR (1) FR2541680B1 (es)
GR (1) GR81662B (es)
HU (1) HU194863B (es)
IE (1) IE56920B1 (es)
NO (1) NO169388C (es)
NZ (1) NZ207244A (es)
SU (1) SU1318164A3 (es)
ZA (1) ZA841274B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1956906A4 (en) 2005-11-09 2009-12-30 Combinatorx Inc METHODS, COMPOSITIONS AND KITS FOR THE TREATMENT OF PATHOLOGIES
CN106029076B (zh) 2013-11-18 2019-06-07 福马疗法公司 作为bet溴域抑制剂的苯并哌嗪组合物
TWI742513B (zh) 2013-11-18 2021-10-11 美商弗瑪治療公司 作為bet溴域抑制劑之四氫喹啉組成物
WO2020035826A1 (en) 2018-08-17 2020-02-20 Pi Industries Ltd. 1,2-dithiolone compounds and use thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1498374A (fr) * 1965-06-11 1967-10-20 Agripat Sa Produits fongicides et bactéricides, utilisables en agriculture
US3527867A (en) * 1965-06-11 1970-09-08 Geigy Chem Corp Agents inhibiting fungus growth and method of controlling fungi therewith
US3772273A (en) * 1969-01-17 1973-11-13 Allied Chem Derivatives of quinoxaline
US3984405A (en) * 1971-06-28 1976-10-05 E. R. Squibb & Sons, Inc. Anti-inflammatory agents
BE795970A (fr) * 1972-02-29 1973-08-27 Pfizer Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant
JPS5819644B2 (ja) * 1975-03-13 1983-04-19 ウェルファイド株式会社 スイチユウボウオザイ
FR2347928A1 (fr) * 1976-04-15 1977-11-10 Rhone Poulenc Ind Nouveaux derives du dithiole-1,2, leur preparation et les compositions qui les contiennent
SE444319B (sv) * 1977-11-18 1986-04-07 Roussel Uclaf Nya imidazobensoxazinderivat, forfarande for framstellning derav och farmaceutiska kompositioner innehallande dessa foreningar
US4254118A (en) * 1979-08-13 1981-03-03 Ayerst, Mckenna & Harrison Inc. 1-Oxo-5H-pyrimido[2,1-c][1,4]benzthiazine-2-carboxylic acid esters
US4273773A (en) * 1979-09-24 1981-06-16 American Home Products Corporation Antihypertensive tricyclic isoindole derivatives
US4477378A (en) * 1980-02-05 1984-10-16 Schering Corp. Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
CA1211437A (en) * 1981-08-12 1986-09-16 Rene Borer Benzazepines

Also Published As

Publication number Publication date
SU1318164A3 (ru) 1987-06-15
IE840418L (en) 1984-08-24
AU2485584A (en) 1984-08-30
DK93984D0 (da) 1984-02-23
NO169388B (no) 1992-03-09
CA1227197A (fr) 1987-09-22
US4576954A (en) 1986-03-18
KR900006745B1 (ko) 1990-09-20
NZ207244A (en) 1986-12-05
FR2541680B1 (fr) 1985-06-14
NO840698L (no) 1984-08-27
JPS59163383A (ja) 1984-09-14
KR840008025A (ko) 1984-12-12
DE3460896D1 (en) 1986-11-13
DK159111B (da) 1990-09-03
HUT35663A (en) 1985-07-29
HU194863B (en) 1988-03-28
ES529986A0 (es) 1984-11-01
EP0119896B1 (fr) 1986-10-08
GR81662B (es) 1984-12-12
ZA841274B (en) 1984-09-26
DK159111C (da) 1991-02-11
AU567718B2 (en) 1987-12-03
FR2541680A1 (fr) 1984-08-31
IE56920B1 (en) 1992-01-29
EP0119896A1 (fr) 1984-09-26
DK93984A (da) 1984-08-25
NO169388C (no) 1992-06-17
ATE22690T1 (de) 1986-10-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303