ES8405801A1 - Procedimiento para la obtencion de 2-ariltetraazaindenos. - Google Patents

Procedimiento para la obtencion de 2-ariltetraazaindenos.

Info

Publication number
ES8405801A1
ES8405801A1 ES522254A ES522254A ES8405801A1 ES 8405801 A1 ES8405801 A1 ES 8405801A1 ES 522254 A ES522254 A ES 522254A ES 522254 A ES522254 A ES 522254A ES 8405801 A1 ES8405801 A1 ES 8405801A1
Authority
ES
Spain
Prior art keywords
alkenyl
alkyl
alkynyl
groups
tetraazaindenes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES522254A
Other languages
English (en)
Other versions
ES522254A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of ES8405801A1 publication Critical patent/ES8405801A1/es
Publication of ES522254A0 publication Critical patent/ES522254A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/28—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups having unsaturation outside the aromatic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 2-ARILTETRAAZAINDENOS, DE FORMULA GENERAL (I), EN LA QUE A SIGNIFICA -NFCH-CHFN O -CHFN-NFCH-; Y AR SIGNIFICA UN RESTO FENILO INDUSTITUIDO O UN RESTO FENILO SUSTITUIDO POR GRUPOS HIDROXI, MERCAPTO O DIALQUILAMINO, Y SUS SALES FISIOLOGICAMENTE COMPATIBLES.CONSISTE EN HACER REACCIONAR UNA DIAMINA DE FORMULA GENERAL (II), EN LA QUE EL GRUPO -A- TIENE EL SIGNIFICADO YA INDICADO, CON UN ACIDO BENZOICO, DE FORMULA GENERAL (III), EN LA QUE AR TIENE EL SIGNIFICADO YA INDICADO, O CON UNO DE SUS DERIVADOS REACTIVOS O CON UN ALDEHIDO DE FORMULAGENERAL (IV), EN LA QUE AR TIENE EL SIGNIFICADO YA MENCIONADO, EN PRESENCIA DE UN AGENTE OXIDANTE.DE APLICACION EN EL TRATAMIENTO DE INSUFICIENCIAS CARDIACAS, O EN EL TRATAMIENTO TERAPEUTICO DEL CUERPO HUMANO O ANIMAL.
ES522254A 1982-05-11 1983-05-10 Procedimiento para la obtencion de 2-ariltetraazaindenos. Granted ES522254A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823217583 DE3217583A1 (de) 1982-05-11 1982-05-11 2-aryl-tetraazaindene

Publications (2)

Publication Number Publication Date
ES8405801A1 true ES8405801A1 (es) 1984-06-16
ES522254A0 ES522254A0 (es) 1984-06-16

Family

ID=6163227

Family Applications (1)

Application Number Title Priority Date Filing Date
ES522254A Granted ES522254A0 (es) 1982-05-11 1983-05-10 Procedimiento para la obtencion de 2-ariltetraazaindenos.

Country Status (10)

Country Link
US (3) US4477454A (es)
EP (1) EP0093951B1 (es)
JP (1) JPS58206590A (es)
AT (1) ATE23163T1 (es)
AU (1) AU559472B2 (es)
DE (2) DE3217583A1 (es)
ES (1) ES522254A0 (es)
HU (1) HU188452B (es)
IL (1) IL68612A (es)
ZA (1) ZA833342B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758574A (en) * 1982-05-03 1988-07-19 Eli Lilly And Company 2-phenylimidazio (4,5-c) pyridines
US4904785A (en) * 1982-05-03 1990-02-27 Eli Lilly And Company 2-phenylimidazo[4,5-c]pyridines
DE3217583A1 (de) * 1982-05-11 1983-11-17 Merck Patent Gmbh, 6100 Darmstadt 2-aryl-tetraazaindene
DE3324115A1 (de) * 1983-07-05 1985-01-17 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3346640A1 (de) * 1983-12-23 1985-07-04 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazolderivate, deren herstellung und diese verbindungen enthaltende arzneimittel
DE3347290A1 (de) * 1983-12-28 1985-07-11 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 2-phenyl-imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel
US4740599A (en) * 1986-10-03 1988-04-26 Eli Lilly And Company Synthesis of alkylsulfinyl substituted 2-phenylimidazo(4,5-c)pyridines
AT389105B (de) * 1988-02-23 1989-10-25 Gerot Pharmazeutika Neue aromatische aldehyde, ihre herstellung und verwendung
JPH0621106B2 (ja) * 1988-03-15 1994-03-23 日本ペイント株式会社 極性基を有するアリールオキシアレン化合物ならびにその製法
USRE43432E1 (en) * 2000-08-08 2012-05-29 Dow Global Technologies Llc Polyurethane foam composition
JP5289264B2 (ja) * 2009-10-06 2013-09-11 タキカワエンジニアリング株式会社 移動体用温度計
US8376663B2 (en) * 2010-03-10 2013-02-19 Mantissa Corporation Segmented conveyor and air film chute

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3244715A (en) * 1964-10-30 1966-04-05 Smith Kline French Lab Phenylimidazo [4, 5-d] pyridazines
US3660397A (en) * 1970-04-17 1972-05-02 Merck & Co Inc Imidazo(4 5-b)pyrazines
US4072746A (en) * 1975-10-14 1978-02-07 Sterling Drug Inc. 3-Amino-5-(pyridinyl)-2(1H)-pyridinones
DE2927987A1 (de) * 1979-07-11 1981-02-05 Thomae Gmbh Dr K Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel
DE3044497A1 (de) * 1980-11-26 1982-06-24 Dr. Karl Thomae Gmbh, 7950 Biberach Neues verfahren zur herstellung von imidazo(4,5-b)pyridinen und -pyrimidinen
DE3217583A1 (de) * 1982-05-11 1983-11-17 Merck Patent Gmbh, 6100 Darmstadt 2-aryl-tetraazaindene
DE3346640A1 (de) * 1983-12-23 1985-07-04 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazolderivate, deren herstellung und diese verbindungen enthaltende arzneimittel
DE3347290A1 (de) * 1983-12-28 1985-07-11 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 2-phenyl-imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
DE3217583A1 (de) 1983-11-17
AU559472B2 (en) 1987-03-12
US4654344A (en) 1987-03-31
US4477454A (en) 1984-10-16
JPS58206590A (ja) 1983-12-01
AU1440883A (en) 1983-11-17
US4575505A (en) 1986-03-11
IL68612A (en) 1987-10-30
ZA833342B (en) 1984-01-25
EP0093951A3 (en) 1984-08-01
IL68612A0 (en) 1983-09-30
ATE23163T1 (de) 1986-11-15
HU188452B (en) 1986-04-28
DE3367218D1 (de) 1986-12-04
EP0093951A2 (de) 1983-11-16
EP0093951B1 (de) 1986-10-29
ES522254A0 (es) 1984-06-16

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