ES8407485A1 - Un procedimiento de preparacion de nuevos 1(2-carbalcoxi-4-(tienilalquilamido) fenoxi)3-amino 2-propanoles utilizables en terapeutica. - Google Patents

Un procedimiento de preparacion de nuevos 1(2-carbalcoxi-4-(tienilalquilamido) fenoxi)3-amino 2-propanoles utilizables en terapeutica.

Info

Publication number
ES8407485A1
ES8407485A1 ES524103A ES524103A ES8407485A1 ES 8407485 A1 ES8407485 A1 ES 8407485A1 ES 524103 A ES524103 A ES 524103A ES 524103 A ES524103 A ES 524103A ES 8407485 A1 ES8407485 A1 ES 8407485A1
Authority
ES
Spain
Prior art keywords
thienylalkylamido
propanols
carbalkoxy
phenoxy
therapy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524103A
Other languages
English (en)
Other versions
ES524103A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Carpibem SA
Original Assignee
Carpibem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8212499A external-priority patent/FR2530245A1/fr
Priority claimed from FR8309361A external-priority patent/FR2546890B2/fr
Application filed by Carpibem SA filed Critical Carpibem SA
Publication of ES524103A0 publication Critical patent/ES524103A0/es
Publication of ES8407485A1 publication Critical patent/ES8407485A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 1-2-CARBALCOXI-4-(TIEN ILALQUILAMIDO) FENOXI-3-AMINO-2-PROPANOLES, DE FORMULA (I), EN LA QUE N VALE 0 O 1; Y R, R1 Y R2 PUEDEN SER VARIOS TIPOS DE RADICALES; COMPUESTOS QUE TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA HIPERTENSION.CONSISTE EN LA REACCION DE UNA BASE DE FORMULA NH2-R1 CON UN COMPUESTO DE FORMULA (II), EN LAS QUE N, R, R1 Y R2 TIENEN LOS MISMOS SIGNIFICADOS QUE EN LA FORMULA (I). LA REACCION SE EFECTUA EN AUSENCIA O PRESENCIA DE UN DISOLVENTE ORGANICO, A UNA TEMPERATURA ENTRE 20JC Y 150JC.
ES524103A 1982-07-16 1983-07-14 Un procedimiento de preparacion de nuevos 1(2-carbalcoxi-4-(tienilalquilamido) fenoxi)3-amino 2-propanoles utilizables en terapeutica. Expired ES8407485A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8212499A FR2530245A1 (fr) 1982-07-16 1982-07-16 Nouveaux 1-(2-carbalkoxy 4-(thienyl-alkylamido)phenoxy) 3-amino 2-propanols, leur preparation et leurs applications en therapeutique
FR8309361A FR2546890B2 (fr) 1983-06-06 1983-06-06 Nouveaux derives substitues du 1-(2-carbalkoxy 4-(thienyl carboxamido phenoxy) 3-amino 2-propanol, leur preparation et leurs applications en therapeutique

Publications (2)

Publication Number Publication Date
ES524103A0 ES524103A0 (es) 1984-10-01
ES8407485A1 true ES8407485A1 (es) 1984-10-01

Family

ID=26222995

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524103A Expired ES8407485A1 (es) 1982-07-16 1983-07-14 Un procedimiento de preparacion de nuevos 1(2-carbalcoxi-4-(tienilalquilamido) fenoxi)3-amino 2-propanoles utilizables en terapeutica.

Country Status (10)

Country Link
US (1) US4668801A (es)
EP (1) EP0099822B1 (es)
AU (1) AU566089B2 (es)
CA (1) CA1205478A (es)
DE (1) DE3367389D1 (es)
DK (1) DK164552C (es)
ES (1) ES8407485A1 (es)
GR (1) GR79194B (es)
IE (1) IE56108B1 (es)
PT (1) PT77031B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268389A (en) * 1989-10-16 1993-12-07 Uniroyal Chemical Company, Inc. Thiocarboxylate ester compounds compositions containing the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1543689A (fr) * 1966-11-03 1968-10-25 Ici Ltd Procédé de fabrication de nouvelles alcanolamines et de leurs dérivés
GB1185044A (en) * 1966-11-03 1970-03-18 Ici Ltd Alkanolamine Derivatives
GB1531718A (en) * 1974-11-20 1978-11-08 Pharmacia As Phenylethanolamines
DE2923817C2 (de) * 1979-06-12 1981-07-09 A. Nattermann & Cie GmbH, 5000 Köln (3-Alkylamino-2-hydroxyproposy)-furan-2-carbonsäureanilide und deren physiologisch verträgliche Säureadditionssalze und Verfahren zu deren Herstellung sowie Arzneimittel mit einem Gehalt dieser Verbindungen
FR2510573B1 (fr) * 1981-07-29 1985-07-26 Carpibem (2-substitue 4-(thienyl acetamido) phenoxy) hydroxy propylamines, leur preparation, leur utilisation en therapeutique, et nouveaux intermediaires
ZA827646B (en) * 1981-11-12 1983-08-31 American Hospital Supply Corp Esters of aryloxypropanolamine derivatives

Also Published As

Publication number Publication date
GR79194B (es) 1984-10-22
DK326883A (da) 1984-01-17
PT77031B (fr) 1986-01-28
EP0099822A1 (fr) 1984-02-01
PT77031A (fr) 1983-08-01
IE831496L (en) 1984-01-16
DK164552B (da) 1992-07-13
AU1686883A (en) 1984-01-19
ES524103A0 (es) 1984-10-01
AU566089B2 (en) 1987-10-08
DE3367389D1 (en) 1986-12-11
US4668801A (en) 1987-05-26
IE56108B1 (en) 1991-04-24
EP0099822B1 (fr) 1986-11-05
DK164552C (da) 1992-11-30
DK326883D0 (da) 1983-07-15
CA1205478A (en) 1986-06-03

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519