ES8403917A1 - "un metodo de producir un compuesto de cefalosporina". - Google Patents

"un metodo de producir un compuesto de cefalosporina".

Info

Publication number
ES8403917A1
ES8403917A1 ES515593A ES515593A ES8403917A1 ES 8403917 A1 ES8403917 A1 ES 8403917A1 ES 515593 A ES515593 A ES 515593A ES 515593 A ES515593 A ES 515593A ES 8403917 A1 ES8403917 A1 ES 8403917A1
Authority
ES
Spain
Prior art keywords
salt
compound
chem
formula
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES515593A
Other languages
English (en)
Other versions
ES515593A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP14330281A external-priority patent/JPS5843979A/ja
Priority claimed from JP666882A external-priority patent/JPS58124793A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ES8403917A1 publication Critical patent/ES8403917A1/es
Publication of ES515593A0 publication Critical patent/ES515593A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus
    • C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

METODO PARA PRODUCIR UN COMPUESTO DE CEFALOSPORINA, DE FORMULA GENERAL (I), EN LA QUE R1 ES UN ATOMO DE HIDROGENO O UN GRUPO ACILO; R ES HIDROGENO O UN RESTO DE ESTER; R4 ES UN RESTO DE UN COMPUESTO NUCLEOFILO.CONSISTE EN HACER REACCIONAR, EN UN DISOLVENTE ORGANICO, UN COMPUESTO DE FORMULA (II), EN LA QUE R1, R Y LA LINEA DE PUNTOS TIENEN LOS SIGNIFICADOS YA MENCIONADOS, O UNA SAL DEL MISMO, CON UN COMPUESTO CICLICO DE FOSFORO TRIVALENTE O PENTAVALENTE QUE TIENE UNA ESTRUCTURA DE FORMULA (III), EN LA QUE W ES UN ATOMO DE OXIGENO OUN ATOMO DE AZUFRE; W1 ES UN ATOMO DE OXIGENO O NR3; Y R2 Y R3 PUEDEN SER IGUALES O DIFERENTES Y CADA UNO DE ELLOS SIGNIFICAN HIDROGENO O UN GRUPO HIDROCARBONADO.DE APLICACION COMO COMPUESTO INTERMEDIO PARA LA PREPARACION DE COMPUESTOS DE CEFALOSPORINA.
ES515593A 1981-09-10 1982-09-09 "un metodo de producir un compuesto de cefalosporina". Granted ES515593A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14330281A JPS5843979A (ja) 1981-09-10 1981-09-10 セフアロスポリン化合物の製造方法
JP666882A JPS58124793A (ja) 1982-01-18 1982-01-18 １，３，２−ジオキサホスホ−ル類の製造法

Publications (2)

Publication Number Publication Date
ES8403917A1 true ES8403917A1 (es) 1984-04-01
ES515593A0 ES515593A0 (es) 1984-04-01

Family

ID=26340854

Family Applications (1)

Application Number Title Priority Date Filing Date
ES515593A Granted ES515593A0 (es) 1981-09-10 1982-09-09 "un metodo de producir un compuesto de cefalosporina".

Country Status (9)

Country Link
US (1) US4801703A (es)
EP (2) EP0135683B1 (es)
KR (1) KR890002915B1 (es)
CA (1) CA1219856A (es)
DE (1) DE3276809D1 (es)
DK (1) DK163925C (es)
ES (1) ES515593A0 (es)
GB (2) GB2147900B (es)
PT (1) PT75530B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110848131A (zh) * 2019-11-22 2020-02-28 北京蓝星清洗有限公司 一种高温清洗低聚物的泵站及高温清洗低聚物的方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ198350A (en) * 1980-09-25 1985-02-28 Toyama Chemical Co Ltd Cephalosporins and intermediates;pharmaceutical compositions
ES2052501T3 (es) * 1986-02-28 1994-07-16 Takeda Chemical Industries Ltd Metodo para la produccion de compuestos de cefalosporina.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2382622A (en) * 1944-01-03 1945-08-14 Victor Chemical Works Glycol esters of phenylphosphonic acid
BE633481A (es) * 1962-06-12
FR1360130A (fr) * 1962-06-12 1964-04-30 Sumitomo Chemical Co Esters phosphatiques cycliques ayant des effets insecticides et nematicides et leur procédé de production
US3773711A (en) * 1970-11-23 1973-11-20 Borg Warner Substituted 4,5-benzo-1-oxa-3-thia-2-phospholane
BE792453A (fr) * 1971-12-10 1973-06-08 Ciba Geigy Esters cycliques d'acides du phosphore et produits pesticides qui en contiennent
GB1565941A (en) * 1977-02-08 1980-04-23 Toyama Chemical Co Ltd Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids
JPS6027677B2 (ja) * 1978-07-06 1985-06-29 富山化学工業株式会社 ７−置換又は非置換アミノ−３−置換チオメチルセフエムカルボン酸類の新規製造法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110848131A (zh) * 2019-11-22 2020-02-28 北京蓝星清洗有限公司 一种高温清洗低聚物的泵站及高温清洗低聚物的方法

Also Published As

Publication number Publication date
EP0135683A1 (en) 1985-04-03
EP0074611A2 (en) 1983-03-23
GB2147900B (en) 1986-06-25
DK163925C (da) 1992-09-14
CA1219856A (en) 1987-03-31
DE3276809D1 (en) 1987-08-27
EP0074611B1 (en) 1987-07-22
KR840001584A (ko) 1984-05-07
DK400882A (da) 1983-03-11
DK163925B (da) 1992-04-21
GB8427294D0 (en) 1984-12-05
GB2108114B (en) 1985-07-17
EP0135683B1 (en) 1987-07-22
GB2147900A (en) 1985-05-22
KR890002915B1 (ko) 1989-08-11
GB2108114A (en) 1983-05-11
CA1260004C (es) 1989-09-26
PT75530B (en) 1984-12-12
ES515593A0 (es) 1984-04-01
PT75530A (en) 1982-10-01
EP0074611A3 (en) 1984-05-23
US4801703A (en) 1989-01-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20011110