ES8403873A1 - Un procedimiento para la obtencion de sales de amino (e imino) acidos (alfa) w -sulfonicos n-sustituidos. - Google Patents
Un procedimiento para la obtencion de sales de amino (e imino) acidos (alfa) w -sulfonicos n-sustituidos.Info
- Publication number
- ES8403873A1 ES8403873A1 ES523839A ES523839A ES8403873A1 ES 8403873 A1 ES8403873 A1 ES 8403873A1 ES 523839 A ES523839 A ES 523839A ES 523839 A ES523839 A ES 523839A ES 8403873 A1 ES8403873 A1 ES 8403873A1
- Authority
- ES
- Spain
- Prior art keywords
- imino
- acids
- substituted
- salts
- omega
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- 125000002091 cationic group Chemical group 0.000 title 1
- 230000001413 cellular effect Effects 0.000 title 1
- 125000001841 imino group Chemical group [H]N=* 0.000 title 1
- 230000035515 penetration Effects 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000013598 vector Substances 0.000 title 1
- 101000740162 Homo sapiens Sodium- and chloride-dependent transporter XTRP3 Proteins 0.000 abstract 2
- -1 IMINO Chemical class 0.000 abstract 2
- RADKZDMFGJYCBB-UHFFFAOYSA-N Pyridoxal Chemical compound CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 abstract 2
- 102100037189 Sodium- and chloride-dependent transporter XTRP3 Human genes 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 229910006069 SO3H Inorganic materials 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 229960003581 pyridoxal Drugs 0.000 abstract 1
- 235000008164 pyridoxal Nutrition 0.000 abstract 1
- 239000011674 pyridoxal Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8211768A FR2529546A1 (fr) | 1982-07-05 | 1982-07-05 | Nouveaux sels d'amino-(et imino-)acides a, o-sulfoniques n-substitues, vecteurs cationiques de haute penetration cellulaire |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES523839A0 ES523839A0 (es) | 1984-04-01 |
| ES8403873A1 true ES8403873A1 (es) | 1984-04-01 |
Family
ID=9275686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES523839A Expired ES8403873A1 (es) | 1982-07-05 | 1983-07-04 | Un procedimiento para la obtencion de sales de amino (e imino) acidos (alfa) w -sulfonicos n-sustituidos. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4563470A (enExample) |
| EP (1) | EP0099799B1 (enExample) |
| JP (1) | JPS6055067B2 (enExample) |
| AT (1) | ATE18552T1 (enExample) |
| DE (1) | DE3362536D1 (enExample) |
| ES (1) | ES8403873A1 (enExample) |
| FR (1) | FR2529546A1 (enExample) |
| PT (1) | PT76970B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ543319A (en) * | 1999-04-28 | 2007-06-29 | Neurochem Int Ltd | Compositions and methods for treating amyloidosis using sulphonate derivatives |
| US6562836B1 (en) * | 1999-05-24 | 2003-05-13 | Queen's University Of Kingston | Methods and compounds for inhibiting amyloid deposits |
| US7414076B2 (en) * | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US7244764B2 (en) * | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US20070010573A1 (en) * | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
| BRPI0517790A (pt) * | 2004-11-12 | 2008-10-21 | Neurochem Int Ltd | métodos e composições fluoradas para tratar doenças relacionadas à amilóide |
| CA2586334A1 (en) * | 2004-11-16 | 2006-06-08 | Neurochem (International) Limited | Compounds for the treatment of cns and amyloid associated diseases |
| WO2006085149A2 (en) | 2004-12-22 | 2006-08-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| KR101608445B1 (ko) * | 2006-10-12 | 2016-04-01 | 비에이치아이 리미티드 파트너쉽 | 3-아미노-1-프로판설폰산을 전달하기 위한 방법, 화합물, 조성물 및 비히클 |
-
1982
- 1982-07-05 FR FR8211768A patent/FR2529546A1/fr active Granted
-
1983
- 1983-06-30 PT PT76970A patent/PT76970B/pt unknown
- 1983-07-01 US US06/510,347 patent/US4563470A/en not_active Expired - Fee Related
- 1983-07-04 EP EP83401373A patent/EP0099799B1/fr not_active Expired
- 1983-07-04 AT AT83401373T patent/ATE18552T1/de not_active IP Right Cessation
- 1983-07-04 ES ES523839A patent/ES8403873A1/es not_active Expired
- 1983-07-04 DE DE8383401373T patent/DE3362536D1/de not_active Expired
- 1983-07-05 JP JP58122258A patent/JPS6055067B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| PT76970B (fr) | 1986-01-24 |
| JPS5921666A (ja) | 1984-02-03 |
| JPS6055067B2 (ja) | 1985-12-03 |
| ES523839A0 (es) | 1984-04-01 |
| EP0099799B1 (fr) | 1986-03-12 |
| ATE18552T1 (de) | 1986-03-15 |
| FR2529546B1 (enExample) | 1985-02-08 |
| EP0099799A1 (fr) | 1984-02-01 |
| PT76970A (fr) | 1983-07-01 |
| FR2529546A1 (fr) | 1984-01-06 |
| US4563470A (en) | 1986-01-07 |
| DE3362536D1 (en) | 1986-04-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19980202 |