ATE18552T1 - Salze von alpha-amino(und imino)-saeure, omegasulfon n-substituiert, kationische vektoren mit hoher cellularer penetration und herstellungsverfahren. - Google Patents
Salze von alpha-amino(und imino)-saeure, omegasulfon n-substituiert, kationische vektoren mit hoher cellularer penetration und herstellungsverfahren.Info
- Publication number
- ATE18552T1 ATE18552T1 AT83401373T AT83401373T ATE18552T1 AT E18552 T1 ATE18552 T1 AT E18552T1 AT 83401373 T AT83401373 T AT 83401373T AT 83401373 T AT83401373 T AT 83401373T AT E18552 T1 ATE18552 T1 AT E18552T1
- Authority
- AT
- Austria
- Prior art keywords
- omegasulfone
- imino
- alpha
- salts
- amino
- Prior art date
Links
- 101000740162 Homo sapiens Sodium- and chloride-dependent transporter XTRP3 Proteins 0.000 title 1
- -1 IMINO Chemical class 0.000 title 1
- 102100037189 Sodium- and chloride-dependent transporter XTRP3 Human genes 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 230000001413 cellular effect Effects 0.000 title 1
- 230000035515 penetration Effects 0.000 title 1
- 239000013598 vector Substances 0.000 title 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8211768A FR2529546A1 (fr) | 1982-07-05 | 1982-07-05 | Nouveaux sels d'amino-(et imino-)acides a, o-sulfoniques n-substitues, vecteurs cationiques de haute penetration cellulaire |
| EP83401373A EP0099799B1 (fr) | 1982-07-05 | 1983-07-04 | Nouveaux sels d'amino- (et imino-) acides alpha, omega-sulfoniques N-substitués, vecteurs cationiques de haute pénétration cellulaire, procédé d'obtention |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE18552T1 true ATE18552T1 (de) | 1986-03-15 |
Family
ID=9275686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83401373T ATE18552T1 (de) | 1982-07-05 | 1983-07-04 | Salze von alpha-amino(und imino)-saeure, omegasulfon n-substituiert, kationische vektoren mit hoher cellularer penetration und herstellungsverfahren. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4563470A (enExample) |
| EP (1) | EP0099799B1 (enExample) |
| JP (1) | JPS6055067B2 (enExample) |
| AT (1) | ATE18552T1 (enExample) |
| DE (1) | DE3362536D1 (enExample) |
| ES (1) | ES523839A0 (enExample) |
| FR (1) | FR2529546A1 (enExample) |
| PT (1) | PT76970B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0010099A (pt) * | 1999-04-28 | 2002-06-04 | Univ Kingston | Métodos para modular a agregação de amilóides em um indivìduo, para o tratamento de um estado doentio associado com amiloidose, composição para modular amiloidose, e, métodos para inibir os depósitos de amilóide associados com iapp em um indivìduo, para inibir fibrilogenese iapp em um indivìduo, para reduzir os agregados de amilóides associados com iapp em um indivìduo, para modular dano associado com amilóides em células, e para modular amiloidose in vivo ou ex vivo |
| US6562836B1 (en) | 1999-05-24 | 2003-05-13 | Queen's University Of Kingston | Methods and compounds for inhibiting amyloid deposits |
| US20070010573A1 (en) * | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
| US7414076B2 (en) * | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US7244764B2 (en) * | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| EP1828111A2 (en) * | 2004-11-12 | 2007-09-05 | Neurochem (International) Limited | Methods and fluorinated compositions for treating amyloid-related diseases |
| CA2586334A1 (en) * | 2004-11-16 | 2006-06-08 | Neurochem (International) Limited | Compounds for the treatment of cns and amyloid associated diseases |
| US8044100B2 (en) * | 2004-12-22 | 2011-10-25 | Bellus Health Inc. | Methods and compositions for treating amyloid-related diseases |
| EP2862581B1 (en) | 2006-10-12 | 2021-08-11 | BHI Limited Partnership | Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid |
-
1982
- 1982-07-05 FR FR8211768A patent/FR2529546A1/fr active Granted
-
1983
- 1983-06-30 PT PT76970A patent/PT76970B/pt unknown
- 1983-07-01 US US06/510,347 patent/US4563470A/en not_active Expired - Fee Related
- 1983-07-04 AT AT83401373T patent/ATE18552T1/de not_active IP Right Cessation
- 1983-07-04 ES ES523839A patent/ES523839A0/es active Granted
- 1983-07-04 DE DE8383401373T patent/DE3362536D1/de not_active Expired
- 1983-07-04 EP EP83401373A patent/EP0099799B1/fr not_active Expired
- 1983-07-05 JP JP58122258A patent/JPS6055067B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| PT76970A (fr) | 1983-07-01 |
| PT76970B (fr) | 1986-01-24 |
| FR2529546B1 (enExample) | 1985-02-08 |
| EP0099799B1 (fr) | 1986-03-12 |
| ES8403873A1 (es) | 1984-04-01 |
| EP0099799A1 (fr) | 1984-02-01 |
| US4563470A (en) | 1986-01-07 |
| JPS5921666A (ja) | 1984-02-03 |
| JPS6055067B2 (ja) | 1985-12-03 |
| ES523839A0 (es) | 1984-04-01 |
| FR2529546A1 (fr) | 1984-01-06 |
| DE3362536D1 (en) | 1986-04-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |