ES8401093A1 - "proceso para la produccion de 5,3',4',6"-tetradesoxikanamicina b". - Google Patents

"proceso para la produccion de 5,3',4',6"-tetradesoxikanamicina b".

Info

Publication number
ES8401093A1
ES8401093A1 ES514621A ES514621A ES8401093A1 ES 8401093 A1 ES8401093 A1 ES 8401093A1 ES 514621 A ES514621 A ES 514621A ES 514621 A ES514621 A ES 514621A ES 8401093 A1 ES8401093 A1 ES 8401093A1
Authority
ES
Spain
Prior art keywords
aminoalkanoyl
omega
deoxykanamycin
compounds
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES514621A
Other languages
English (en)
Other versions
ES514621A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP55109854A external-priority patent/JPS5753496A/ja
Priority claimed from JP56058389A external-priority patent/JPS57175198A/ja
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of ES514621A0 publication Critical patent/ES514621A0/es
Publication of ES8401093A1 publication Critical patent/ES8401093A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCESO PARA LA PRODUCCION DE 5,3,4,6-TETRADESOXIKANAMICI NA B.SE EFECTUAN LAS SIGUIENTES ETAPAS: 1) PROTEGER EL GRUPO 4L-HIDROXILO DE UN DERIVADO PENTA-N-PROTEGIDO Y 2L-O-PROTEGIDO DE 3,4,6L-TRIDESOXIKANAMICINA B. 2) HACER REACCIONAR EL COMPUESTO (II) OBTENIDO CON CLORURO DE SULFURILO PARA REEMPLAZAR SU GRUPO 5-HIDROXILO CON UN ATOMO DE CLORO PARA PRODUCIR EL CORRESPONDIENTE DERIVADO 5-CLORO. 3) REDUCIR DICHO DERIVADO PARA RETIRAR EL GRUPO 5-CLORO PARA PRODUCIR UN DERIVADO PROTEGIDO DE 5,3,4,6L-TETRADESOXIKANAMICINA B. 4) RETIRAR LOS GRUPOS HIDROXILO RESTANTES Y LOS GRUPOS AMINO-PROTECTORES RESTANTESPOR PROCEDIMIENTOS CONOCIDOS PARA OBTENER EL COMPUESTO (I).
ES514621A 1980-08-12 1982-07-31 "proceso para la produccion de 5,3',4',6"-tetradesoxikanamicina b". Expired ES8401093A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP55109854A JPS5753496A (en) 1980-08-12 1980-08-12 1-n-acyl derivative of 5,3',4'-trideoxykanamycin b or 5,3',4',6'- tetradeoxykanamycin b, and their preparation
JP56058389A JPS57175198A (en) 1981-04-20 1981-04-20 1-n-acyl derivative of 5,3,4-trideoxy-6-n-methylkanamycin b and their preparation

Publications (2)

Publication Number Publication Date
ES514621A0 ES514621A0 (es) 1983-12-16
ES8401093A1 true ES8401093A1 (es) 1983-12-16

Family

ID=26399440

Family Applications (4)

Application Number Title Priority Date Filing Date
ES504697A Expired ES8301486A1 (es) 1980-08-12 1981-08-11 Nuevos derivados 1-n-(x-hidroxi-w-aminoalcanoil)de 5,3'4'- tridesoxi-o 5,3,4'-tridesoxi-6'-n-metil-o 5,3',4',6 -tetra- desoxi-kanamicina b y produccion de los mismos
ES514620A Granted ES514620A0 (es) 1980-08-12 1982-07-31 "proceso para la produccion de una 1-n-(-hidroxi-aminoalcanoil)-5,3',4'-tridesoxi-6'-n-metilkanamicina b".
ES514622A Granted ES514622A0 (es) 1980-08-12 1982-07-31 "proceso para la produccion de 5,3',4'-tridesoxi-6'-n-metilkanamicina b".
ES514621A Expired ES8401093A1 (es) 1980-08-12 1982-07-31 "proceso para la produccion de 5,3',4',6"-tetradesoxikanamicina b".

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES504697A Expired ES8301486A1 (es) 1980-08-12 1981-08-11 Nuevos derivados 1-n-(x-hidroxi-w-aminoalcanoil)de 5,3'4'- tridesoxi-o 5,3,4'-tridesoxi-6'-n-metil-o 5,3',4',6 -tetra- desoxi-kanamicina b y produccion de los mismos
ES514620A Granted ES514620A0 (es) 1980-08-12 1982-07-31 "proceso para la produccion de una 1-n-(-hidroxi-aminoalcanoil)-5,3',4'-tridesoxi-6'-n-metilkanamicina b".
ES514622A Granted ES514622A0 (es) 1980-08-12 1982-07-31 "proceso para la produccion de 5,3',4'-tridesoxi-6'-n-metilkanamicina b".

Country Status (9)

Country Link
KR (1) KR850000979B1 (es)
CA (1) CA1175816A (es)
CH (1) CH648564A5 (es)
DE (1) DE3131731C2 (es)
ES (4) ES8301486A1 (es)
FR (1) FR2491073A1 (es)
GB (1) GB2082575B (es)
IT (1) IT1167959B (es)
NL (1) NL8103639A (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS554118B2 (es) * 1973-08-29 1980-01-29

Also Published As

Publication number Publication date
ES8308334A1 (es) 1983-08-16
IT8109493A0 (it) 1981-08-07
ES504697A0 (es) 1982-12-01
IT1167959B (it) 1987-05-20
ES514621A0 (es) 1983-12-16
ES514622A0 (es) 1983-08-16
DE3131731C2 (de) 1984-02-16
ES8301486A1 (es) 1982-12-01
ES8401092A1 (es) 1983-12-16
GB2082575B (en) 1984-04-18
FR2491073A1 (fr) 1982-04-02
CA1175816A (en) 1984-10-09
CH648564A5 (de) 1985-03-29
DE3131731A1 (de) 1982-03-11
GB2082575A (en) 1982-03-10
ES514620A0 (es) 1983-12-16
NL8103639A (nl) 1982-03-01
FR2491073B1 (es) 1984-08-03
KR830006325A (ko) 1983-09-24
KR850000979B1 (ko) 1985-07-05

Similar Documents

Publication Publication Date Title
JPS5759865A (en) Heterocyclic compounds, manufacture and medicinal compound containing same
ES466483A1 (es) Un procedimiento para la preparacion de derivados de azol
ES8203375A1 (es) Procedimiento de preparar triazoloquinoxalin-4-onas substi- tuidas antihipertensoras
EP0177940A3 (en) Hydrazine derivatives and their use
AU6633981A (en) Non-staining antigingivitis composition
IL59829A (en) Derivatives of 9,10-anthracene-bis-carboxaldehyde-bis-hydrazone
AU7338081A (en) 1,2,4-triazolylpropenol derivatives
JPS5776000A (en) Organic compound, manufacture and medicinal compound containing same
AU526672B2 (en) Penicillanoyloxymethyl penicillanate 1,1,1:,1:-tetraoxide
AU543946B2 (en) Derivatives of 4h-1,2,4-triazole
AU545556B2 (en) Use of dihydro-1h-pyrollizine 3,5 dione as a cognition activator
NZ194046A (en) Certain 6,7-disubstituted-3-methyl-1,2,3,5-tetrahydro-imidazo (2,1-b)quinazolin-2-ones
ES8205214A1 (es) Un procedimiento para la preparacion de un derivado de 3-o- desmetilsannamicina c o del antibiotico ax-127b-1.
IE810767L (en) Prepartion of 2, 2, 6, 6-tetramethylpiperidone-4.
ES8403103A1 (es) Procedimiento para la preparacion de derivados de pantenol.
ES8308334A1 (es) "proceso para la produccion de 5,3',4'-tridesoxi-6'-n-metilkanamicina b".
AU544360B2 (en) 6-hydrazono-pyrido(2,1-b)quinazoline-11-ones
AU539995B2 (en) 2,3-dihydro-2,2-dimethylbenzofuran derivatives
JPS56161367A (en) Manufacture of 3-mercapto-propanediol-(1,2)
AU1968883A (en) 15-cycloaliphatic derivatives of 13,14-didehydro- carboprostacyclins
AU7906381A (en) Tetrahydro-1,2,4-oxadiazin-5-one derivatives
SU1032912A1 (ru) Фотохромный материал
SU1269296A1 (ru) Гербицидный состав
AU542710B2 (en) 16-amino-17-phenyl-18,19,20-trinor-prosta-glandin derivatives
JO1006B1 (en) New factors that lower blood pressure