JPS57175198A - 1-n-acyl derivative of 5,3,4-trideoxy-6-n-methylkanamycin b and their preparation - Google Patents

1-n-acyl derivative of 5,3,4-trideoxy-6-n-methylkanamycin b and their preparation

Info

Publication number
JPS57175198A
JPS57175198A JP56058389A JP5838981A JPS57175198A JP S57175198 A JPS57175198 A JP S57175198A JP 56058389 A JP56058389 A JP 56058389A JP 5838981 A JP5838981 A JP 5838981A JP S57175198 A JPS57175198 A JP S57175198A
Authority
JP
Japan
Prior art keywords
amino
methylkanamycin
trideoxy
preparation
acyl derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56058389A
Other languages
Japanese (ja)
Other versions
JPH0134230B2 (en
Inventor
Hamao Umezawa
Shinichi Kondo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP56058389A priority Critical patent/JPS57175198A/en
Priority to KR1019810002784A priority patent/KR850000979B1/en
Priority to NL8103639A priority patent/NL8103639A/en
Priority to IT09493/81A priority patent/IT1167959B/en
Priority to CH5133/81A priority patent/CH648564A5/en
Priority to FR8115781A priority patent/FR2491073A1/en
Priority to DE3131731A priority patent/DE3131731C2/en
Priority to GB8124490A priority patent/GB2082575B/en
Priority to DE19813152755 priority patent/DE3152755C2/en
Priority to ES504697A priority patent/ES504697A0/en
Priority to CA000383690A priority patent/CA1175816A/en
Priority to ES514621A priority patent/ES514621A0/en
Priority to ES514622A priority patent/ES8308334A1/en
Priority to ES514620A priority patent/ES8401092A1/en
Publication of JPS57175198A publication Critical patent/JPS57175198A/en
Publication of JPH0134230B2 publication Critical patent/JPH0134230B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The compound of formulaI(n is 1, 2 or 3).
EXAMPLE: 1-N-[3-Amino-2-hydroxypropionyl]-5, 3', 4'-trideoxy-6'-N-methylkanamycin B.
USE: Antibacterial agent for resistant bacteria.
PROCESS: The compound of formulaIcan be prepared, e.g. by protecting at least a part of the three amino groups other than the 1-position amino group and the methylamino group of 5,3',4'-trideoxy-6'-methylkanamycin B of formula II with amino-protecting groups, acylating the 1-position amino group with ω- amino-α-hydroxyalkanoic acid of formula III (n is 1W3), its amino-protected derivative or their reactive derivatives, and eliminating the amino-protecting groups by conventional method.
COPYRIGHT: (C)1982,JPO&Japio
JP56058389A 1980-08-12 1981-04-20 1-n-acyl derivative of 5,3,4-trideoxy-6-n-methylkanamycin b and their preparation Granted JPS57175198A (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
JP56058389A JPS57175198A (en) 1981-04-20 1981-04-20 1-n-acyl derivative of 5,3,4-trideoxy-6-n-methylkanamycin b and their preparation
KR1019810002784A KR850000979B1 (en) 1980-08-12 1981-07-31 Method of preparing 5,3',4'-trideoxy-or 5,3',4'-trideoxy-6'-n-methyl-or 5,3',4'6"-tetradeoxy-kanamy-cin b or-1-n-(alpha-hydroxy-w-aminoalkanoyl) derivatives
NL8103639A NL8103639A (en) 1980-08-12 1981-07-31 NEW 1-N (ALFA-HYDROXY-OMEGA-AMINOALKANOYL) DERIVATIVES OF 5.3 ', 4'-TRIDEOXY, 5.3', 4'-TRIDEOXY-6'-METHYL-OR 5.3 ', 4 6 "-TETRADEOXYKANAMYCIN-B, AND METHOD FOR PREPARING THEREOF.
IT09493/81A IT1167959B (en) 1980-08-12 1981-08-07 1-N- (ALPHA-HYDROXY-OMEGA-AMINOALCANOIL) DERIVATIVES OF 5,3 ', 4', - TRIDEOXY- 0 5,3 ', 4'-TRIDEOXY-6'-N-METHYL-0 5,3', 4 ', 6-TETRADEOSSI-KANAMICINA BE PRODUCTION OF THEM
CH5133/81A CH648564A5 (en) 1980-08-12 1981-08-10 IF NECESSARY, 1-N-ACYLATED 5,3,4-TRIDEOXY- OR 5,3,4-TRIDEOXY-6-N-METHYL- OR 5,3,4,6-TETRADEOXYKANAMYCIN-B AND METHOD FOR THE PRODUCTION THEREOF.
FR8115781A FR2491073A1 (en) 1980-08-12 1981-08-10 NEW 5,3 ', 4'-TRIDESOXY- OR 5,3', 4'-TRIDESOXY-6'-N-METHYL OR 5,3 ', 4-N- (α-HYDROXY-O-AMINOALCANOYL) DERIVATIVES ', 6' '- TETRADESOXYKANAMYCIN B, METHODS FOR THEIR PRODUCTION AND ANTIBACTERIAL COMPOSITIONS COMPRISING THEM
DE3131731A DE3131731C2 (en) 1980-08-12 1981-08-11 5,3 ', 4'-Trideoxykanamycins B substituted on the 6'- or / and 1-amino group, process for their preparation and antibacterial agents containing these compounds
GB8124490A GB2082575B (en) 1980-08-12 1981-08-11 1-n-(hydroxy-w-aminoalkanoyl) derivatives of deoxykanamycin b compounds
DE19813152755 DE3152755C2 (en) 1980-08-12 1981-08-11 Tri:and tetra:deoxy kanamycin B derivs. - useful as broad spectrum antibacterials
ES504697A ES504697A0 (en) 1980-08-12 1981-08-11 NEW 1-N- (X-HYDROXY-W-AMINOALKANOYL) DERIVATIVES OF 5,3'4'- TRIDESOXY-O 5,3,4'-TRIDESOXY-6'-N-METHYL-O 5,3 ', 4' , 6 -TETRA- DESOXI-KANAMYCIN BY PRODUCTION OF THE SAME
CA000383690A CA1175816A (en) 1980-08-12 1981-08-12 1-N-(.alpha.-HYDROXY-.omega.-AMINOALKANOYL) DERIVATIVES OF 5, 3',4'-TRIDEOXY- OR 5,3',4'-TRIDEOXY-6'-N-METHYL- OR 5,3',4',6"-TETRADEOXY-KANAMYCIN B AND PRODUCTION THEREOF
ES514621A ES514621A0 (en) 1980-08-12 1982-07-31 "PROCESS FOR THE PRODUCTION OF 5,3 ', 4', 6" -TETRADESOXIKANAMICINA B ".
ES514622A ES8308334A1 (en) 1980-08-12 1982-07-31 1-N-( alpha hydroxy - omega - aminoalkanoyl) derivatives of deoxykanamycin B compounds
ES514620A ES8401092A1 (en) 1980-08-12 1982-07-31 1-N-( alpha hydroxy - omega - aminoalkanoyl) derivatives of deoxykanamycin B compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56058389A JPS57175198A (en) 1981-04-20 1981-04-20 1-n-acyl derivative of 5,3,4-trideoxy-6-n-methylkanamycin b and their preparation

Publications (2)

Publication Number Publication Date
JPS57175198A true JPS57175198A (en) 1982-10-28
JPH0134230B2 JPH0134230B2 (en) 1989-07-18

Family

ID=13082982

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56058389A Granted JPS57175198A (en) 1980-08-12 1981-04-20 1-n-acyl derivative of 5,3,4-trideoxy-6-n-methylkanamycin b and their preparation

Country Status (1)

Country Link
JP (1) JPS57175198A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5148634A (en) * 1974-10-08 1976-04-26 Microbial Chem Res Found Taiseikinnyukona 11nn * arufua hidorokishi omega aminoashiru * 6**nn mechiru 3* *hh jideokishikanamaishin b no seizoho
JPS5459255A (en) * 1977-10-14 1979-05-12 Suami T 55deoxykanamicin b and production thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5148634A (en) * 1974-10-08 1976-04-26 Microbial Chem Res Found Taiseikinnyukona 11nn * arufua hidorokishi omega aminoashiru * 6**nn mechiru 3* *hh jideokishikanamaishin b no seizoho
JPS5459255A (en) * 1977-10-14 1979-05-12 Suami T 55deoxykanamicin b and production thereof

Also Published As

Publication number Publication date
JPH0134230B2 (en) 1989-07-18

Similar Documents

Publication Publication Date Title
HU900228D0 (en) Process for preparation of pyrazolo-pyridines
HUT50345A (en) Process for production of cefem-derivatives and their intermediers
JPS5791998A (en) Novel 5'-o-acylnucleoside derivative and its preparation
IL83978A (en) Process and compositions containing dihalopyridine derivatives for protecting plants against diseases,certain such novel derivatives and their preparation
PT80038A (en) Process for the preparation of spergualin <(-)-(15s)-1-amino-1 9-guanidin-11,15-dihydroxi-4,9,12-triazanonedecano> compounds with a phenylene group and pharmaceutical compositions therewith
DE3572914D1 (en) Process for preparation of compositions for modifying plant growth; composition for plant growth modification: and method for the use thereof
EP0072528A3 (en) (thio)ureas, their preparation, their use as plant protecting agents and intermediates for their production
JPS57175198A (en) 1-n-acyl derivative of 5,3,4-trideoxy-6-n-methylkanamycin b and their preparation
JPS55111463A (en) Beta-lactam compound and its preparation
JPS554337A (en) Cephalosporin analogs
JPS5753496A (en) 1-n-acyl derivative of 5,3',4'-trideoxykanamycin b or 5,3',4',6'- tetradeoxykanamycin b, and their preparation
ES8403889A1 (en) 1,4-Dihydropyridine compound and a preparation method thereof.
CA2062788A1 (en) Improved process for preparing isepamicin
ZA825718B (en) Compound with antiulcerogenic activity, process for the preparation thereof and pharmaceutical compositions therefrom
JPS55164672A (en) Azetidine derivative and its preparation
HU913540D0 (en) Process for the protection of plant cultivation by using triazolyl- or imidazolyl-methyl-allyl-alcoholes, and the new compounds used in the process
JPS57200398A (en) 3"-n-methyl-4"-c-methyl-3',4'-deoxykanamycin b or 1-n-acyl derivative of its 4"-epimer and its preparation
ES8400397A1 (en) New peptide, process for preparation thereof and use thereof.
DE3370960D1 (en) 3,7-dichloro-8-quinoline derivatives, process for their preparation and their use to combat undesired plant growth
JPS56138180A (en) Di-n6',o3-demethylistamycin a and its preparation
JPS52128394A (en) Novel adenine derivatives and plant jormone containing the same
JPS5716856A (en) 4-guanidinomethylcyclohexanecarboxylic acid ester and its preparation
IL66821A0 (en) 1,2,3-thiadiazol-5-yl-urea derivatives,processes for their preparation and compositions for plant growth regulation containing the same
DE3260879D1 (en) 1-iodo-1-propyn-3-ols, process for their preparation and their use as plant protecting agents
JPS5214730A (en) Process for preparation of m-toluidine containing protected p-amino gr oup