ES8401011A1 - Procedimiento para preparar derivados 3-aminopropoxifenili- cos. - Google Patents
Procedimiento para preparar derivados 3-aminopropoxifenili- cos.Info
- Publication number
- ES8401011A1 ES8401011A1 ES506842A ES506842A ES8401011A1 ES 8401011 A1 ES8401011 A1 ES 8401011A1 ES 506842 A ES506842 A ES 506842A ES 506842 A ES506842 A ES 506842A ES 8401011 A1 ES8401011 A1 ES 8401011A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 3-Aminopropoxyphenyl Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 101000740162 Homo sapiens Sodium- and chloride-dependent transporter XTRP3 Proteins 0.000 abstract 1
- 206010020850 Hyperthyroidism Diseases 0.000 abstract 1
- 238000010934 O-alkylation reaction Methods 0.000 abstract 1
- 102100037189 Sodium- and chloride-dependent transporter XTRP3 Human genes 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 208000029078 coronary artery disease Diseases 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 150000003141 primary amines Chemical class 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 208000005057 thyrotoxicosis Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
- C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
- C07C43/2055—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring containing more than one ether bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH824980 | 1980-11-06 | ||
| CH934780 | 1980-12-18 | ||
| CH407381 | 1981-06-19 | ||
| CH407481 | 1981-06-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES506842A0 ES506842A0 (es) | 1983-12-01 |
| ES8401011A1 true ES8401011A1 (es) | 1983-12-01 |
Family
ID=27428724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES506842A Expired ES8401011A1 (es) | 1980-11-06 | 1981-11-04 | Procedimiento para preparar derivados 3-aminopropoxifenili- cos. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4425362A (en:Method) |
| EP (1) | EP0052072B1 (en:Method) |
| AU (1) | AU555619B2 (en:Method) |
| CA (1) | CA1213594A (en:Method) |
| DE (1) | DE3169095D1 (en:Method) |
| DK (1) | DK161310C (en:Method) |
| ES (1) | ES8401011A1 (en:Method) |
| FI (1) | FI76551C (en:Method) |
| GR (1) | GR75384B (en:Method) |
| IE (1) | IE51919B1 (en:Method) |
| IL (1) | IL64213A (en:Method) |
| NZ (1) | NZ198867A (en:Method) |
| PH (1) | PH23009A (en:Method) |
| PT (1) | PT73929B (en:Method) |
| YU (1) | YU42592B (en:Method) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE19510T1 (de) * | 1981-12-17 | 1986-05-15 | Haessle Ab | Para-substituierte 3-phenoxy-1carbonylaminoalkylaminopropan-2-ole mit blockierenden wirkungen bei betarezeptoren. |
| US4463176A (en) * | 1982-09-13 | 1984-07-31 | Mead Johnson & Company | Process for resolution of optical isomers |
| DE3380093D1 (en) * | 1982-09-30 | 1989-07-27 | William John Louis | 3-aminopropoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them |
| US5238962A (en) * | 1983-03-03 | 1993-08-24 | Hoffmann-La Roche Inc. | Benzamide derivatives |
| IL78783A (en) * | 1985-05-14 | 1990-08-31 | Louis William John | 3-phenoxypropanolamine derivatives,their preparation and pharmaceutical compositions containing them |
| EP0207036A1 (en) * | 1985-06-20 | 1986-12-30 | Aktiebolaget Hässle | New para-substituted 3-phenoxy-1-piperidinecarbonylaminoalkylamino-propanol-2-s having beta receptor blocking properties. |
| US4959390A (en) * | 1988-12-15 | 1990-09-25 | E. I. Du Pont De Nemours And Company | Polyhydroxybenzyloxypropanolamines |
| DE3907512C2 (de) * | 1989-03-08 | 1997-08-14 | Laevosan Gmbh & Co Kg | Neue Aryloxy-alkylamine, deren Herstellung und diese enthaltende Arzneimittel |
| US5380755A (en) * | 1992-07-24 | 1995-01-10 | The Du Pont Merck Pharmaceutical Company | Alkyl and alkylbenzyl ethers of substituted hydroquinones |
| FR2780057B1 (fr) * | 1998-06-18 | 2002-09-13 | Sanofi Sa | Phenoxypropanolamines, procede pour leur preparation et compositions pharmaceutiques les contenant |
| WO2012004549A1 (en) | 2010-07-05 | 2012-01-12 | The University Of Nottingham | Phenoxypropanol derivatives and their use in treating cardiac and cardiovascular diseases |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1455116A (en) * | 1972-12-15 | 1976-11-10 | Ici Ltd | Pharmaceutical compositions |
| GB1457876A (en) * | 1972-12-15 | 1976-12-08 | Ici Ltd | Alkanolamine derivatives device for use in |
| GB1573359A (en) | 1977-12-20 | 1980-08-20 | Ici Ltd | Alkanolamine derivatives |
| GB1521471A (en) | 1974-06-05 | 1978-08-16 | Randall & Son Ltd J | Token-deposit locks |
| FR2330383A1 (fr) | 1975-11-06 | 1977-06-03 | Synthelabo | Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment |
| FR2368951A2 (fr) * | 1976-10-27 | 1978-05-26 | Synthelabo | Nouveaux ethers de phenol |
| DE2914166A1 (de) | 1979-04-07 | 1980-10-23 | Beiersdorf Ag | Arylsubstituierte furane und verfahren zu ihrer herstellung |
-
1981
- 1981-10-30 FI FI813412A patent/FI76551C/fi not_active IP Right Cessation
- 1981-11-02 DE DE8181810439T patent/DE3169095D1/de not_active Expired
- 1981-11-02 EP EP81810439A patent/EP0052072B1/en not_active Expired
- 1981-11-03 PH PH26430A patent/PH23009A/en unknown
- 1981-11-04 US US06/318,292 patent/US4425362A/en not_active Expired - Lifetime
- 1981-11-04 DK DK489381A patent/DK161310C/da not_active IP Right Cessation
- 1981-11-04 IL IL64213A patent/IL64213A/xx not_active IP Right Cessation
- 1981-11-04 ES ES506842A patent/ES8401011A1/es not_active Expired
- 1981-11-04 PT PT73929A patent/PT73929B/pt unknown
- 1981-11-04 GR GR66433A patent/GR75384B/el unknown
- 1981-11-04 IE IE2584/81A patent/IE51919B1/en not_active IP Right Cessation
- 1981-11-04 NZ NZ198867A patent/NZ198867A/en unknown
- 1981-11-05 CA CA000389517A patent/CA1213594A/en not_active Expired
- 1981-11-05 YU YU2632/81A patent/YU42592B/xx unknown
- 1981-11-06 AU AU77171/81A patent/AU555619B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES506842A0 (es) | 1983-12-01 |
| IE812584L (en) | 1982-05-06 |
| DK161310B (da) | 1991-06-24 |
| YU42592B (en) | 1988-10-31 |
| GR75384B (en:Method) | 1984-07-13 |
| PH23009A (en) | 1989-03-03 |
| PT73929A (en) | 1981-12-01 |
| FI76551C (fi) | 1988-11-10 |
| AU555619B2 (en) | 1986-10-02 |
| DK161310C (da) | 1991-12-02 |
| NZ198867A (en) | 1985-07-31 |
| EP0052072B1 (en) | 1985-02-20 |
| IL64213A (en) | 1986-07-31 |
| DK489381A (da) | 1982-05-07 |
| YU263281A (en) | 1984-02-29 |
| IL64213A0 (en) | 1982-02-28 |
| US4425362A (en) | 1984-01-10 |
| IE51919B1 (en) | 1987-04-29 |
| FI76551B (fi) | 1988-07-29 |
| AU7717181A (en) | 1982-05-13 |
| DE3169095D1 (en) | 1985-03-28 |
| PT73929B (en) | 1983-08-16 |
| CA1213594A (en) | 1986-11-04 |
| EP0052072A1 (en) | 1982-05-19 |
| FI813412L (fi) | 1982-05-07 |
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