ES8308315A1 - "procedimiento para la preparacion de nuevos derivados de anilino-1,2,3-triazol". - Google Patents

"procedimiento para la preparacion de nuevos derivados de anilino-1,2,3-triazol".

Info

Publication number
ES8308315A1
ES8308315A1 ES515452A ES515452A ES8308315A1 ES 8308315 A1 ES8308315 A1 ES 8308315A1 ES 515452 A ES515452 A ES 515452A ES 515452 A ES515452 A ES 515452A ES 8308315 A1 ES8308315 A1 ES 8308315A1
Authority
ES
Spain
Prior art keywords
carbon atoms
anilino
preparing
alkyl
triazole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES515452A
Other languages
English (en)
Other versions
ES515452A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Publication of ES515452A0 publication Critical patent/ES515452A0/es
Publication of ES8308315A1 publication Critical patent/ES8308315A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/041,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE ANILINO-1,2,3-TRIAZOL Y DE SUS SALES DE ADICION DE ACIDO, DE FORMULA (I), EN LA QUE R>1 ES ALCOHILO C<1<-<4; R>3 ES HIDROGENO O HALOGENO; R>2, R>4 Y R>5 PUEDEN SER VARIOS RADICALES; Y N VALE 2 O 3. CONSISTE EN LA REACCION DE UN DERIVADO DE TRIAZOL, DE FORMULA (II), CON UN COMPUESTO DE FORMULA X-(CH<2)<N-NR>4R>5, EN LAS QUE X ES UN ATOMO DE HALOGENO Y TODOS LOS DEMAS SIMBOLOS TIENEN LOS MISMOS SIGNIFICADOS QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE POLAR, APROTICO, EN PRESENCIA DE UNA BASE, A TEMPERATURAS MUY VARIABLES. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ALTERACIONES DE LA CIRCULACION SANGUINEA Y DEL SUEÑO.
ES515452A 1981-09-03 1982-09-02 "procedimiento para la preparacion de nuevos derivados de anilino-1,2,3-triazol". Expired ES8308315A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813134842 DE3134842A1 (de) 1981-09-03 1981-09-03 Neue anilino-1,2,3-triazol-derivate, diese enthaltende arzneimittel sowie verfahren zu deren herstellung und deren verwendung

Publications (2)

Publication Number Publication Date
ES515452A0 ES515452A0 (es) 1983-08-16
ES8308315A1 true ES8308315A1 (es) 1983-08-16

Family

ID=6140744

Family Applications (1)

Application Number Title Priority Date Filing Date
ES515452A Expired ES8308315A1 (es) 1981-09-03 1982-09-02 "procedimiento para la preparacion de nuevos derivados de anilino-1,2,3-triazol".

Country Status (19)

Country Link
US (1) US4505912A (es)
EP (1) EP0073931B1 (es)
JP (1) JPS5846073A (es)
KR (1) KR880000729B1 (es)
AR (1) AR231283A1 (es)
AT (1) ATE11776T1 (es)
AU (1) AU550948B2 (es)
CA (1) CA1173035A (es)
DE (2) DE3134842A1 (es)
DK (1) DK393282A (es)
ES (1) ES8308315A1 (es)
FI (1) FI73420C (es)
GB (1) GB2104896B (es)
GR (1) GR76901B (es)
IL (1) IL66704A (es)
NO (1) NO157101C (es)
NZ (1) NZ201795A (es)
PT (1) PT75493B (es)
ZA (1) ZA826414B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR900100380A (el) * 1989-05-20 1991-10-10 Fisons Plc Μέ?οδος παρασκευής αντι-φλεγμονωδών παραγώγων αμινοφενόλης.
TW385308B (en) * 1994-03-04 2000-03-21 Merck & Co Inc Prodrugs of morpholine tachykinin receptor antagonists
CN104884452A (zh) 2012-11-20 2015-09-02 沃泰克斯药物股份有限公司 用作吲哚胺2,3-二氧化酶的抑制剂的化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2714110A (en) * 1954-03-19 1955-07-26 American Cyanamid Co Substituted triazoles and method of preparing same
GB1296911A (es) * 1969-02-26 1972-11-22
US3900492A (en) * 1973-05-29 1975-08-19 Miles Lab Phenyl- and (substituted)-phenyl-1,2,3-triazole-alkanoic and -alkenoic acids
FR2388557A2 (fr) * 1977-04-27 1978-11-24 Ici America Inc Composition pharmaceutique tranquillisante a base de triazole substitue
US4431589A (en) * 1980-12-11 1984-02-14 Lilly House Benzodiazepine compounds and their use as pharmaceuticals

Also Published As

Publication number Publication date
AU8795282A (en) 1983-03-10
AU550948B2 (en) 1986-04-10
IL66704A0 (en) 1982-12-31
EP0073931B1 (de) 1985-02-13
IL66704A (en) 1985-11-29
NO157101B (no) 1987-10-12
FI73420C (fi) 1987-10-09
EP0073931A1 (de) 1983-03-16
KR880000729B1 (ko) 1988-04-29
GB2104896A (en) 1983-03-16
ES515452A0 (es) 1983-08-16
JPS5846073A (ja) 1983-03-17
GR76901B (es) 1984-09-04
FI823000A0 (fi) 1982-08-31
DE3262330D1 (en) 1985-03-28
CA1173035A (en) 1984-08-21
FI73420B (fi) 1987-06-30
NO157101C (no) 1988-01-20
GB2104896B (en) 1985-05-30
DK393282A (da) 1983-03-04
ZA826414B (en) 1984-05-30
FI823000L (fi) 1983-03-04
DE3134842A1 (de) 1983-03-17
NO822969L (no) 1983-03-04
PT75493A (de) 1982-10-01
ATE11776T1 (de) 1985-02-15
AR231283A1 (es) 1984-10-31
US4505912A (en) 1985-03-19
NZ201795A (en) 1985-08-16
PT75493B (de) 1985-11-25

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