ES8405361A1 - Procedimiento para preparar alquenamidas y fenilalquenamidas n,n-disubstituidas. - Google Patents

Procedimiento para preparar alquenamidas y fenilalquenamidas n,n-disubstituidas.

Info

Publication number
ES8405361A1
ES8405361A1 ES518186A ES518186A ES8405361A1 ES 8405361 A1 ES8405361 A1 ES 8405361A1 ES 518186 A ES518186 A ES 518186A ES 518186 A ES518186 A ES 518186A ES 8405361 A1 ES8405361 A1 ES 8405361A1
Authority
ES
Spain
Prior art keywords
phenylalkenamides
alkenamides
pharmaceuticals
4alkyl
disubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518186A
Other languages
English (en)
Other versions
ES518186A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES518186A0 publication Critical patent/ES518186A0/es
Publication of ES8405361A1 publication Critical patent/ES8405361A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Ink Jet Recording Methods And Recording Media Thereof (AREA)
  • Materials For Photolithography (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR ALQUENAMIDAS Y FENILALQUENAMIDAS N.N-DISUSTITUIDAS.CONSISTE EN LA REDUCCION DE UN COMPUESTO DE FORMULA (II), EN PRESENCIA DE UN DISOLVENTE INERTE TAL COMO ETANOL, HIDROGENO Y DE UN CATALIZADOR DE HIDROGENACION TAL COMO PALADIO SOBRE CARBON U OXIDO DE PLATINO, Y A TEMPERATURA ENTRE 20JC A 100JC Y PRESION DE 14 PSI A 100 PSI, PARA OBTENER UN COMPUESTO DE FORMULA (I), EN LA QUE N REPRESENTA 0 O 1; R REPRESENTA ALQUILO DE C 1 A 4 ATOMOS; R2 Y R3 REPRESENTAN ALQUILO DE C 1 A 4 ATOMOS INDISTINTAMENTE; R1 Y R4 REPRESENTAN HALOGENO, ALQUILO DEC 1 A 4 ATOMOS; R5 REPRESENTA ALQUILO DE C 1 A 6 ATOMOS.TIENE APLICACION FARMACOLOGICA PARA EL TRATAMIENTO DE LA DIABETES.
ES518186A 1981-12-14 1982-12-14 Procedimiento para preparar alquenamidas y fenilalquenamidas n,n-disubstituidas. Expired ES8405361A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33060181A 1981-12-14 1981-12-14

Publications (2)

Publication Number Publication Date
ES518186A0 ES518186A0 (es) 1984-06-01
ES8405361A1 true ES8405361A1 (es) 1984-06-01

Family

ID=23290486

Family Applications (1)

Application Number Title Priority Date Filing Date
ES518186A Expired ES8405361A1 (es) 1981-12-14 1982-12-14 Procedimiento para preparar alquenamidas y fenilalquenamidas n,n-disubstituidas.

Country Status (15)

Country Link
US (1) US4681898A (es)
EP (1) EP0084292B1 (es)
JP (1) JPS58110549A (es)
AT (1) ATE11770T1 (es)
AU (1) AU561008B2 (es)
CA (1) CA1191511A (es)
DE (1) DE3262353D1 (es)
DK (1) DK553482A (es)
ES (1) ES8405361A1 (es)
FI (1) FI824298L (es)
HU (1) HU189626B (es)
IL (1) IL67464A (es)
NZ (1) NZ202780A (es)
PT (1) PT75981B (es)
ZA (1) ZA829190B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6846953B1 (en) * 1999-05-10 2005-01-25 Warner Lambert Company Aromatic amides
US20040248972A1 (en) * 2003-05-16 2004-12-09 Ambit Biosciences Corporation Compounds and uses thereof
EP1636183A1 (en) * 2003-05-16 2006-03-22 Ambit Biosciences Corporation Pyrrole compounds and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU168432B (es) * 1973-08-15 1976-04-28
US4061776A (en) * 1975-09-10 1977-12-06 Mitsubishi Chemical Industries Ltd. Pharmaceutically active 2-omega-aminoalkoxydiphenyl ethers
DE3164982D1 (de) * 1980-04-10 1984-08-30 Sandoz Ag Isoxazolyl indolamines
HU187204B (en) * 1982-12-28 1985-11-28 Richter Gedeon Vegyeszet Process for producing new diethyl-amino-alkoxy-benzhydrol derivatives, acid additional salts, and quaternary salts and pharmaceutical compositions contatining them

Also Published As

Publication number Publication date
ES518186A0 (es) 1984-06-01
AU9147682A (en) 1983-06-23
ATE11770T1 (de) 1985-02-15
AU561008B2 (en) 1987-04-30
US4681898A (en) 1987-07-21
NZ202780A (en) 1986-06-11
HU189626B (en) 1986-07-28
JPS58110549A (ja) 1983-07-01
FI824298L (fi) 1983-06-15
IL67464A (en) 1986-08-31
ZA829190B (en) 1984-07-25
PT75981A (en) 1983-01-01
PT75981B (en) 1985-11-20
EP0084292A1 (en) 1983-07-27
CA1191511A (en) 1985-08-06
IL67464A0 (en) 1983-05-15
DE3262353D1 (en) 1985-03-28
DK553482A (da) 1983-06-15
EP0084292B1 (en) 1985-02-13
FI824298A0 (fi) 1982-12-14

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